Abstract: A modular approach for strain sensors for large deformations is provided. The strain sensor separates the extension and signal transduction mechanisms using a soft, elastomeric transmission and a high-sensitivity microelectromechanical system (MEMS) transducer. By separating the transmission and transduction, they can be optimized independently for application-specific mechanical and electrical performance. The durability of the strain sensor was evaluated by conducting cyclic loading tests over one million cycles, and the results show negligible drift. Applications of the strain sensor are suitable for human health monitoring as for example an implantable cardiac strain sensor for measuring global longitudinal strain (GLS).

Abstract: A modular approach for strain sensors for large deformations is provided. The strain sensor separates the extension and signal transduction mechanisms using a soft, elastomeric transmission and a high-sensitivity microelectromechanical system (MEMS) transducer. By separating the transmission and transduction, they can be optimized independently for application-specific mechanical and electrical performance. The durability of the strain sensor was evaluated by conducting cyclic loading tests over one million cycles, and the results show negligible drift. Applications of the strain sensor are suitable for human health monitoring as for example an implantable cardiac strain sensor for measuring global longitudinal strain (GLS).

Abstract: Devices and methods are provided for supporting a subject's heart, e.g., to support the left and/or right ventricles of the heart, e.g., to prevent and/or treat heart failure. In one example, the device includes a sleeve configured to be implanted over a region of the subject's heart including a lattice formed on a surface of the sleeve. The sleeve may be positioned and permanently implanted over a desired region of the subject's heart to provide passive support to ventricular tissue of the heart.

Abstract: Devices are provided for mechanically induced ventricular growth in a single ventricle patient that include a body comprising a plurality of springs coupled together to define an open upper end and a closed lower end, wherein the springs surround an interior region of the body sized to receive a portion of a patient's heart. The device may be secured over a portion of a patient's heart, e.g., overlying the left ventricular region, and the bias of the springs may apply strain to the myocardium of the heart to induce ventricular chamber growth.