Patents by Inventor Ali O. Gure

Ali O. Gure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Colon Cancer Associated Transcript 1 (CCAT1) As A Cancer Marker
    Publication number: 20110097271
    Abstract: The present invention relates to the identification, isolation, and sequencing of a unique nucleic acid transcript termed Colon Cancer Associated Transcript 1 (CCAT-1) that is specifically expressed in cancer cells, in particular in colon, rectal, and lung cancer, as well as in precancerous lesions. The present invention thus provides methods for diagnosing cancer by detecting the expression of CCAT-1 as well as isolated polynucleotides, compositions and kits for use in the detection methods of the invention.
    Type: Application
    Filed: February 11, 2009
    Publication date: April 28, 2011
    Applicants: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LI, LUDWIG INSTITUTE FOR CANCER RESEARCH AND CANCER IN
    Inventors: Aviram Nissan, Stella Mitrani-Rosenbaum, Herbert Rudolf Freund, Tamar Peretz-Yablonsky, Marina Roistacher, Lloyd J. Old, Gerd Ritter, Ali O. Gure
  • Small cell lung cancer associated antigens and uses therefor
    Patent number: 7314721
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with small cell lung cancer. The invention provides, among other things, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: January 1, 2008
    Assignees: Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York Hospital-Cornell Medical Center
    Inventors: Ali O. Gure, Elisabeth Stockert, Matthew J. Scanlan, Dirk Jager, Lloyd J. Old, Yao-Tseng Chen
  • Small cell lung cancer associated antigens and uses therefor
    Publication number: 20040126808
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with small cell lung cancer. The invention provides, inter alia, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided.
    Type: Application
    Filed: January 20, 2004
    Publication date: July 1, 2004
    Inventors: Ali O. Gure, Elisabeth Stockert, Matthew J. Scanlan, Dirk Jager, Lloyd J. Old, Yao-Tseng Chen
  • Antibodies specific for SSX proteins
    Publication number: 20030023057
    Abstract: The invention relates to members of the SSX family of genes, as well as their uses.
    Type: Application
    Filed: October 11, 2001
    Publication date: January 30, 2003
    Inventors: Ali O. Gure, Ozlem Tureci, Ugur Sahin, Solam Tsang, Matthew J. Scanlan, Alexander Knuth, Michael Pfreundschuh, Lloyd J. Old, Yao-Tseng Chen
  • Truncated forms of NY-ESO-1 protein
    Publication number: 20020010321
    Abstract: The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.
    Type: Application
    Filed: December 29, 2000
    Publication date: January 24, 2002
    Inventors: Yao-tseng Chen, Matthew Scanlan, Ali O. Gure, Lloyd J. Old, Ozlem Tureci, Ugur Sahin, Michael Pfreundschuh, Elisabeth Stockert, Elke Jager, Knuth Alexander
  • SSX family proteins
    Patent number: 6339140
    Abstract: The invention relates to members of the SSX family of genes, as well as their uses.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: January 15, 2002
    Assignees: Ludwig Institute for Cancer Research, Cornell Medical Research Foundation, Memorial Sloan Kettering Cancer Center
    Inventors: Ali O. Gure, Ozlem Tureci, Ugur Sahin, Solam Tsang, Matthew J. Scanlan, Alexander Knuth, Michael Pfreundschuh, Lloyd J. Old, Yao-Tseng Chen
  • Isolated nucleic acid molecules encoding SSX family members and thereof
    Patent number: 6291658
    Abstract: The invention relates to members of the SSX family of genes, as well as their uses.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: September 18, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Ali O. Gure, Ozlem Tureci, Ugur Sahin, Solam Tsang, Matthew J. Scanlan, Alexander Knuth, Michael Pfreundschuh, Lloyd J. Old, Yao-Tseng Chen
  • Methods for determining presence of cancer in a sample by determining expression of an SSX gene
    Patent number: 6287756
    Abstract: The invention relates to members of the SSX family of genes, as well as to their uses.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: September 11, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Özlem Türeci, Yao-Tseng Chen, Ugur Sahin, Ali O. Gure, Lloyd J. Old, Michael Pfreundschuh
  • Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof
    Patent number: 6069233
    Abstract: The invention relates to the isolation of a nucleic acid molecule which encodes an esophageal cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: May 30, 2000
    Assignees: Memorial Sloan-Kettering Cancer Center, Cornell Research Foundation, Ludwig Institute for Cancer Research
    Inventors: Yao-tseng Chen, Matthew Scanlan, Ali O. Gure, Lloyd J. Old, Ozlem Tureci, Ugur Sahin, Michael Pfreundschuh