Patents by Inventor Ali REZAIE
Ali REZAIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240041306Abstract: An endoscopic device for use in a patient's body in disclosed. The endoscopic device may include an outer sheath having a proximal end and a distal end, a suction tube inside the outer sheath, a handle coupled to the distal end of the outer sheath, and a cap on the proximal end of the outer sheath, positioned to seal the proximal end of the outer sheath, wherein the outer sheath comprises a sterile appliance, wherein the cap is structured to open in response to a force applied through the suction tube, and wherein the suction tube comprises an internal cavity.Type: ApplicationFiled: August 21, 2023Publication date: February 8, 2024Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Srinivas Gaddam, Simon Lo, Laith Jamil, Kapil Gupta
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Publication number: 20240024697Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body. Here, the inventor(s) developed a system for emission of therapeutic doses of UV light via a catheter, capsule, endoscope, tube or port that can be used to manage internal infections and inflammatory conditions inside a patient.Type: ApplicationFiled: August 2, 2023Publication date: January 25, 2024Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
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Publication number: 20230302292Abstract: Methods and systems one or more for performing intra-luminal ultraviolet therapy for treating and/or ameliorating a gastrointestinal tract inflammation and/or infection are provided. In one example, a light delivery catheter may include a light emitting portion and non-illuminating portion, wherein the light emitting portion may include one or more UV transparent balloons. In some examples, the UV light source is configured to emit narrow-band light having wavelengths in a range between 335 nm and 349 nm.Type: ApplicationFiled: August 13, 2021Publication date: September 28, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
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Publication number: 20230147752Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separating a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space and a cooling tube. In some examples, the UV light source is configured to emit light with wavelengths with a desired intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: March 19, 2021Publication date: May 11, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite, Konstantin Degtyarev, Larry Bischoff, Kuldeep Gandhi, Michael V. Quinn, Richard Cronenberg
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Publication number: 20230038019Abstract: Described herein are compositions and methods of treating gastrointestinal diseases and disorders such as irritable bowel syndrome and small intestinal bacterial overgrowth.Type: ApplicationFiled: March 18, 2020Publication date: February 9, 2023Inventors: Mark PIMENTEL, Gabriela Guimaraes Sousa LEITE, Ruchi MATHUR, Ali REZAIE, Walter MORALES, Stacy WEITSMAN
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Publication number: 20230035292Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: March 14, 2022Publication date: February 2, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Patent number: 11318325Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: GrantFiled: October 21, 2021Date of Patent: May 3, 2022Assignee: Cedars-Sinai Medical CenterInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20220117513Abstract: Provided are systems and methods for collecting and storing a microbiome-derived gaseous sample.Type: ApplicationFiled: October 15, 2021Publication date: April 21, 2022Inventors: Aniruddh PANDIT, Mark PIMENTEL, Kapil GUPTA, Matthew MITCHO, Ali REZAIE
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Publication number: 20220040497Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: October 21, 2021Publication date: February 10, 2022Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Patent number: 11179575Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: GrantFiled: August 13, 2020Date of Patent: November 23, 2021Assignee: Cedars-Sinai Medical CenterInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Patent number: 11103157Abstract: Systems and methods have been developed for implementation of a portable SIBO testing system for convenient sampling of intestinal gases exhaled from a patient's breath. These devices may be in the form of a hand held meter that would integrate with a smartphone or other device with an application that can record data relating to food consumed by a user. Various technologies may be utilized to measure the levels of gases exhaled by a user, which may include (1) sorbent based technology and (2) membrane based technology. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.Type: GrantFiled: August 30, 2016Date of Patent: August 31, 2021Inventors: Kapil Gupta, Mark Pimentel, Ali Rezaie
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Publication number: 20210177303Abstract: Systems and methods have been developed for implementation of a breath testing system for convenient sampling of intestinal gases exhaled from a patient's breath. This may include a system with a manifold that includes thermal regulation components, for instance thermistors and resistive heating elements, which maintain the temperature of the gases above the body temperature of the patient. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.Type: ApplicationFiled: December 16, 2020Publication date: June 17, 2021Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Mark PIMENTEL, Kapil GUPTA, Ali REZAIE, Nicholas David ALLAN, Kristofor Dyck DOLBERG, Nigel Anthony SYROTUCK, Martin Juergen KELLINGHUSEN, Mark Sasha DRLIK, Nathan John MULLER, Kenneth MacCALLUM
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Publication number: 20210161599Abstract: A device, a system, and a method for carrying out an endoscopic procedure in a patient's body using an endoscopic device comprising (a) a tube with a proximal end and a distal end, the distal end coupled to a handle and a proximal end configured to enter into the patient's body, (b) an ultrasound probe on the proximal end of the tube, positioned to emit sound waves to create a visual image of a target site inside the patient's body, and (c) a needle that is configured to be housed inside the tube, wherein the tube includes an internal cavity for a development of the needle.Type: ApplicationFiled: April 15, 2019Publication date: June 3, 2021Inventors: Laith H. JAMIL, Ali REZAIE
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Publication number: 20210106844Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: August 13, 2020Publication date: April 15, 2021Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20200346032Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body. Here, the inventor(s) developed a system for emission of therapeutic doses of UV light via a catheter, capsule, endoscope, tube or port that can be used to manage internal infections and inflammatory conditions inside a patient.Type: ApplicationFiled: July 15, 2020Publication date: November 5, 2020Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
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Publication number: 20200064330Abstract: Described herein are methods of detecting levels hydrogen sulfide (H2S) to diagnose H2S positive disease or conditions. Examples of H2S positive diseases and conditions include small intestinal bacterial overgrowth, diarrhea, fatigue, bowel urgency and abdominal pain. The H2S level can guide treatments for subjects who have high levels of H2S.Type: ApplicationFiled: February 23, 2018Publication date: February 27, 2020Applicant: Cedars-Sinai Medical CenterInventors: Mark Pimentel, Kapil Gupta, Ali Rezaie, Nipaporn Pichetshote
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Publication number: 20200015792Abstract: An endoscopic device for use in a patient's body in disclosed. The endoscopic device may include an outer sheath having a proximal end and a distal end, a suction tube inside the outer sheath, a handle coupled to the distal end of the outer sheath, and a cap on the proximal end of the outer sheath, positioned to seal the proximal end of the outer sheath, wherein the outer sheath comprises a sterile appliance, wherein the cap is structured to open in response to a force applied through the suction tube, and wherein the suction tube comprises an internal cavity.Type: ApplicationFiled: February 22, 2018Publication date: January 16, 2020Applicant: Cedars-Sinai Medical CenterInventors: Ali REZAIE, Mark PIMENTEL, Srinivas GADDAM, Simon LO, Laith JAMIL, Kapil GUPTA
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Publication number: 20190175938Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body.Type: ApplicationFiled: May 31, 2017Publication date: June 13, 2019Applicant: Cedars-Sinai Medical CenterInventors: Ali REZAIE, Mark PIMENTEL, Gil Y. MELMED
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Publication number: 20180271404Abstract: Systems and methods have been developed for implementation of a portable SIBO testing system for convenient sampling of intestinal gases exhaled from a patient's breath. These devices may be in the form of a hand held meter that would integrate with a smartphone or other device with an application that can record data relating to food consumed by a user. Various technologies may be utilized to measure the levels of gases exhaled by a user, which may include (1) sorbent based technology and (2) membrane based technology. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.Type: ApplicationFiled: August 30, 2016Publication date: September 27, 2018Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Kapil GUPTA, Mark PIMENTEL, Ali REZAIE