Patents by Inventor Ali S. Turgiev

Ali S. Turgiev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Integrin Modulators and Methods for Their Use
    Publication number: 20120149940
    Abstract: 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl (DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 14, 2012
    Inventors: John B. Davidson, Ali S. Turgiev
  • Integrin modulators and methods for their use
    Publication number: 20100099917
    Abstract: 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl(DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described.
    Type: Application
    Filed: June 5, 2009
    Publication date: April 22, 2010
    Inventors: John B. Davidson, Ali S. Turgiev
  • Integrin Modulators and Methods for their Use
    Publication number: 20080234388
    Abstract: 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl (DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described.
    Type: Application
    Filed: March 10, 2005
    Publication date: September 25, 2008
    Inventors: John B. Davidson, Ali S. Turgiev
  • Chiral integrin modulators and methods of use thereof
    Patent number: 7321002
    Abstract: The invention provides enantiomers of ajoene and derivatives of Z(?)-ajoene. The derivative of Z(?)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: January 22, 2008
    Assignee: Billings Pharmaceuticals, Inc.
    Inventors: John B. Davidson, Alexander V. Tatarintsev, Ali S. Turgiev, James K. Hildreth
  • Chiral integrin modulators and methods of use thereof
    Patent number: 7045663
    Abstract: The invention provides enantiomers of ajoene and derivtives of Z(?)-ajoene. The derivative of Z(?)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: May 16, 2006
    Assignee: Billings Pharmaceuticals, Inc.
    Inventors: John B. Davidson, Alexander V. Tatarintsev, Ali S. Turgiev, James K. Hildreth
  • Chiral integrin modulators and methods of use thereof
    Publication number: 20040053892
    Abstract: The invention provides enantiomers of a joene and derivtives of Z(−)-ajoene. The derivative of Z(−)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
    Type: Application
    Filed: June 17, 2003
    Publication date: March 18, 2004
    Inventors: John B Davidson, Alexander V Tatarintsev, Ali S Turgiev, James E K Hildreth
  • Methods of using integrin modulators for treatment of inflammation
    Patent number: 6177475
    Abstract: The invention provides methods of treating inflammatory diseases and conditions by administering an effective amount of an integrin modulating agent, as further defined and specified herein, to an animal suffering from one of the diseases or conditions. The preferred integrin modulating agents are ajoene and disintegrins, variants and analogs of disintegrins.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: January 23, 2001
    Assignee: Billings Pharmaceuticals, Inc.
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson
  • Methods of using Ajoene for inhibiting integrin-mediated cell-cell fusion
    Patent number: 5981602
    Abstract: The present invention relates to the use of ajoene for inhibiting integrin-mediated cell-cell fusion. Specific types of cell-cell fusion are giant multinucleated cell formation, syneytia formation, and osteoclast formation.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: November 9, 1999
    Assignee: John B. Davidson
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson
  • Methods of using ajoene
    Patent number: 5948821
    Abstract: The progression of infection and other pathologies produced by a viral infection may be inhibited by administering an effective dosage of Ajoene. Additionally, Ajoene has anti-tumor, anti-shock, and antiinflammation effects. In general, Ajoene may be used to treat any integrin-mediated disease or condition.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: September 7, 1999
    Assignee: John B. Davidson
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson
  • Methods of using ajoene to inhibit an immune response
    Patent number: 5863955
    Abstract: This invention relates to a method of inhibiting an immune response by administering an effective dosage of Ajoene.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: January 26, 1999
    Assignee: John B. Davidson
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson
  • Contraceptive method using ajoene
    Patent number: 5863954
    Abstract: The progression of infection and other pathologies produced by a viral infection may be inhibited by administering an effective dosage of Ajoene. Additionally, Ajoene has anti-tumor, anti-shock, and anti-inflammation effects. In general, Ajoene may be used to treat any integrin-mediated disease or condition.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: January 26, 1999
    Assignee: John B. Davidson
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson
  • Methods of using ajoene
    Patent number: 5856363
    Abstract: The progression of infection and other pathologies produced by a viral infection may be inhibited by administering an effective dosage of Ajoene. Additionally, Ajoene has anti-tumor, anti-shock, and anti-inflammation effects. In general, Ajoene may be used to treat any integrin-mediated disease or condition.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: January 5, 1999
    Assignee: John B. Davidson
    Inventors: Alexander V. Tatarintsev, Ali S. Turgiev, John B. Davidson