Patents by Inventor Alice CHEN-PLOTKIN

Alice CHEN-PLOTKIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPY FOR FRONTOTEMPORAL DEMENTIA
    Publication number: 20190328906
    Abstract: The invention provides methods and uses for delivering progranulin to the central nervous system (CNS) of a mammal. Methods and uses include, for example, administering to a mammal a vector comprising a nucleic acid encoding progranulin, variant, derivative or functional fragment thereof to the mammal's brain ventricle to transduce CNS cells and/or cells that contact the cerebrospinal fluid (CSF) of the mammal such that the cells express the progranulin, variant, derivative or functional fragment thereof.
    Type: Application
    Filed: March 2, 2017
    Publication date: October 31, 2019
    Applicants: The Children's Hospital of Philadelphia, The Trustees of the University of Pennsylvania
    Inventors: Alice CHEN PLOTKIN, Defne AMADO, Julianne REIDERS, Beverly L. DAVIDSON
  • A PARKINSON'S DISEASE DIAGNOSTIC BIOMARKER PANEL
    Publication number: 20170335395
    Abstract: The present invention relates to a method of diagnosing Parkinson's disease in a subject using a novel set of biomarkers. The invention further includes compositions, methods and uses of a novel set of biomarkers to assess the risk of developing Parkinson's disease, to provide pre-symptomatic diagnosis of Parkinson's disease, and to assess prognosis of Parkinson's disease following therapeutic or other intervention.
    Type: Application
    Filed: October 26, 2015
    Publication date: November 23, 2017
    Inventors: Alice CHEN-PLOTKIN, Benjamine LIU, Christine SWANSON