Patents by Inventor Alice G. Cheng

Alice G. Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods related to protein A (SpA) variants
    Patent number: 11939358
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: March 26, 2024
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • HIGH-COMPLEXITY SYNTHETIC GUT BACTERIAL COMMUNITIES
    Publication number: 20230233620
    Abstract: The present invention provides high-complexity defined gut microbial communities capable of achieving substantial engraftment and having stability following human fecal community microbial challenge and methods of producing the same. Also provided are methods of using high-complexity defined gut microbial communities for the treatment of dysbiosis or a pathological condition in an animal.
    Type: Application
    Filed: May 21, 2021
    Publication date: July 27, 2023
    Inventors: Michael A. Fischbach, Ariel R. Brumbaugh, Alice G. Cheng, Dylan Dodd, Andres Jesus Aranda-Diaz, Min Wang, Feiqiao Brian Yu, Justin L. Sonnenburg, Kerwyn C. Huang, Steve Higginbottom, Sunit Jain, Xiandong Meng, Lee Swem, Dante Ricci, Joshua J. Hamilton
  • HIGH COMPLEXITY SYNTHETIC GUT BACTERIAL COMMUNITIES
    Publication number: 20220023354
    Abstract: The present invention provides high-complexity defined gut microbial communities capable of achieving substantial engraftment and having stability following human fecal community microbial challenge and methods of producing the same. Also provided are methods of using high-complexity defined gut microbial communities for the treatment of dysbiosis or a pathological condition in an animal.
    Type: Application
    Filed: November 21, 2019
    Publication date: January 27, 2022
    Inventors: Michael A. Fischbach, Ariel R. Brumbaugh, Alice G. Cheng, Dylan Dodd, Justin L. Sonnenburg, Kerwyn C. Huang, Andres Jesus Aranda-Diaz, Steve Higginbottom, Min Wang, Feiqiao Brian Yu
  • Compositions and Methods Related to Protein A (SpA) Variants
    Publication number: 20210290748
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 23, 2021
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and methods related to protein A (SpA) variants
    Patent number: 11059866
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: July 13, 2021
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and Methods Related to Protein A (SpA) Variants
    Publication number: 20200140494
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: October 23, 2019
    Publication date: May 7, 2020
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and methods related to Protein A (SpA) Variants
    Patent number: 10464971
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: November 5, 2019
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and Methods Related to Protein A (SpA) Variants
    Publication number: 20170369536
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: September 12, 2017
    Publication date: December 28, 2017
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and Methods Related to Protein A (SpA) Variants
    Publication number: 20160194363
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: March 4, 2016
    Publication date: July 7, 2016
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and methods related to protein A (SpA) variants
    Patent number: 9315554
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: April 19, 2016
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Methods and compositions involving protective staphylococcal antigens
    Patent number: 9095540
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: August 4, 2015
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim, Hye-Young Kim
  • COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) VARIANTS
    Publication number: 20150056240
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Inventors: Olaf SCHNEEWIND, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
    Patent number: 8945588
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Ebh antigen.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: February 3, 2015
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and methods related to protein A (SpA) variants
    Patent number: 8821894
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: September 2, 2014
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • METHODS AND COMPOSITIONS INVOLVING PROTECTIVE STAPHYLOCOCCAL ANTIGENS
    Publication number: 20130230550
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.
    Type: Application
    Filed: September 9, 2011
    Publication date: September 5, 2013
    Applicant: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim, Hye-Young Kim
  • METHODS AND COMPOSITIONS INVOLVING PROTECTIVE STAPHYLOCOCCAL ANTIGENS, SUCH AS EBH POLYPEPTIDES
    Publication number: 20120282247
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Ebh antigen.
    Type: Application
    Filed: May 7, 2012
    Publication date: November 8, 2012
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim