Publication number: 20040142331
Abstract: The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
Type:
Application
Filed:
August 11, 2003
Publication date:
July 22, 2004
Inventors:
Stuart E Jackson, Stephen E Lincoln, Christina M Altus, Gerard E Dufour, Michael S Chalup, Jennier L Jackson, Anissa L Jones, Jimmy Y Yu, Rachel J Wright, Darryl Gietzen, Tommy F Liu, Pierre E Yap, Christopher R Dahl, Monika G Momiyama, Diana L Bradley, Sameer D Rohatgi, Bernard Harris, Ann M Roseberry Lincoln, Edward H Gerstin, Careyna H Peralta, Marie H David, Scott R Panzer, Vincent Z Flores, Abel Daffo, Rakesh Marwaha, Alice J Chen, Simon C Chang, Alan P Au, Rebekah R Inman
Publication number: 20040048253
Abstract: The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
Type:
Application
Filed:
June 5, 2003
Publication date:
March 11, 2004
Inventors:
Scott R. Panzer, Peter A. Spiro, Steven C. Banville, Purvi Shah, Michael S. Chalup, Simon C Chang, Alice J. Chen, Steven A. D'Sa, Stefan Amshey, Christopher E. Dahl, Tam C. Dam, Susan E. Daniels, Gerard E. Dufour, Vincent Flores, Willy T. Fong, Lila B. Greenawalt, Jennifer L. Jackson, Anissa L. Jones, Tommy F. Liu, Ann M. Roseberry Lincoln, Bruce H. Rosen, Frank D. Russo, Theresa K. Stockdreher, Abel Daffo, Rachel J. Wright, Pierre E. Yap, Jimmy Y. Yu, Diana L. Bradley, Shawn R. Bratcher, Wensheng Chen, Howard J. Cohen, David M. Hodgson, Stephen E. Lincoln, Stuart E. Jackson