Abstract: Interleukin-2 (IL-2) conjugates comprising at least one or more amino acid substitutions that bias binding to the IL-2 receptor ??c dimer over binding the IL-2 receptor ???c trimer and a non-natural amino acid at or near the N-terminus conjugated to a water-soluble polymer are described. The IL-2 conjugates are useful for treatment and prevention of cell proliferation and cancer in a patient.

Abstract: The present disclosure describes a high-throughput methodology for rapid and highly personalized screenings to identify efficacious anti-tumor immunotherapy regiments. In one embodiment, therapeutic agents or a combination thereof are screened by co-culturing tumor shaped organoid extrudates with a population of immune cells taken from the same patient. Reduced tumor cell functions or increased immune cell functions in the presence of the therapeutic agents or combination thereof would identify the therapeutic agents or combination thereof for treating the tumor in the patient.

Abstract: A headband for a headset and a method for producing the headband for the headset is disclosed. The headband is configured to carry at least one earcup of the headset. The headband comprises a carrier and a rubber suspension formed by overmolding. The method comprising the steps of providing the carrier, arranging the carrier in an injection molding tool, and forming the suspension from a rubber material by overmolding such that the suspension forms at least two attachment points to the carrier.

Abstract: A headband for a headset and a method for producing the headband for the headset is disclosed. The headband is configured to carry at least one earcup of the headset. The headband comprises a carrier and a rubber suspension formed by overmolding. The method comprising the steps of providing the carrier, arranging the carrier in an injection molding tool, and forming the suspension from a rubber material by overmolding such that the suspension forms at least two attachment points to the carrier.

Abstract: A headband for a headset and a method for producing the headband for the headset is disclosed. The headband is configured to carry at least one earcup of the headset. The headband comprises a carrier and a rubber suspension formed by overmolding. The method comprising the steps of providing the carrier, arranging the carrier in an injection molding tool, and forming the suspension from a rubber material by overmolding such that the suspension forms at least two attachment points to the carrier.

Abstract: Systems and methods are provided for oligomerization of olefins to distillate boiling range products while also recycling naphtha boiling range olefins as part of the feed. By performing the olefin oligomerization while also recycling naphtha boiling range olefins, it has been discovered that the resulting distillate boiling range products can have an unexpected improvement in diesel combustion quality, such as an unexpected improvement in cetane rating. In order to manage coke formation and maintain consistent activity profile for the oligomerization catalyst, the reaction can be performed in a moving bed reactor. Additional temperature control can be maintained by the recycling of the naphtha boiling range portions of the oligomerization product back to the reactor.

Abstract: Systems and methods are provided for oligomerization of olefins to distillate boiling range products while also recycling naphtha boiling range olefins as part of the feed. By performing the olefin oligomerization while also recycling naphtha boiling range olefins, it has been discovered that the resulting distillate boiling range products can have an unexpected improvement in diesel combustion quality, such as an unexpected improvement in cetane rating. In order to manage coke formation and maintain consistent activity profile for the oligomerization catalyst, the reaction can be performed in a moving bed reactor. Additional temperature control can be maintained by the recycling of the naphtha boiling range portions of the oligomerization product back to the reactor.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Abstract: A computer-implemented method includes transmitting tax related data to a selected financial institution, reporting the data and remitting funds corresponding to the data, over an interactive communications network, to a selected government authority. XML-based transaction requests and responses may be used to facilitate the method.

Abstract: A bolometer is provided for use in an infrared imager. The bolometer comprises a substrate and a TiOx layer formed over the substrate. The TiOx layer has a resistance responsive to temperature. The x value of the TiOx layer is in the range of 1.68 to 1.95.

Abstract: This disclosure relates to a specific, illustrative apparatus, system and method for transmitting tax related data to a selected financial institution, reporting the data and remitting funds corresponding to the data, over an interactive communications network, to a selected government authority. The system comprises a first function for receiving an XML-based transaction request from a program controlled tax computation system. This function also verifies the validity of the request and replies to the system with an XML-based response, preferably including a transaction identifier. A second function, desirably modular in form, verifies the validity of the XML form request from the tax computation system. It also stores such valid transaction request in a database. Next, a third function transforms the request into a master XML-based request and stores the master request in the database. A fourth function then notifies an authorized third party, i.e.

Abstract: This disclosure relates to a specific, illustrative multilayer architecture for a program controlled system for providing services relating to financial data computation, report remittance and funds transfer over an interactive communications network. The system comprises a subscriber server for hosting a virtual portal having at least one application for providing e-content to end users, the application including a network browser for accessing, displaying and transmitting data over the network. A first service provider server allows a system administrator to access the system remotely. A first security system protects the system from entry of unwanted data during data transfer over the network between the subscriber and service provider servers and the interactive communications network level. Also provided are plurality of primary servers including a primary network server, a primary tax computation server, a primary report generation server and a primary tax remittance server.