Patents by Inventor Alice M. Brinkman

Alice M. Brinkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Flavivirus Antigens
    Publication number: 20160151478
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: November 16, 2015
    Publication date: June 2, 2016
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Recombinant dengue virus antigen comprising the capsid protein leader sequence, full-length prM protein, and full-length E protein
    Patent number: 9186397
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 17, 2015
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • RECOMBINANT DENGUE VIRUS ANTIGEN COMPRISING THE CAPSID PROTEIN LEADER SEQUENCE, FULL-LENGTH prM PROTEIN, AND FULL-LENGTH E PROTEIN.
    Publication number: 20150290313
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: March 11, 2014
    Publication date: October 15, 2015
    Applicant: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Recombinant dengue virus antigen comprising the capsid protein leader sequence, full-length prM protein, and full-length E protein
    Patent number: 8715694
    Abstract: The invention provides polypeptides and virus-like particles having, for example, an ability to induce an immune response to flaviviruses. The polypeptides can include C15, prM, and E polypeptide sequences.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 6, 2014
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Novel Flavivirus Antigens
    Publication number: 20120282287
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: April 16, 2012
    Publication date: November 8, 2012
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Nucleic acids encoding novel chimeric C15/prM/E dengue virus immunogens prepared by DNA shuffling
    Patent number: 8168772
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: May 1, 2012
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Recombinant dengue virus antigens comprising the C15 signal peptide, full-length PRM protein, and full-length E protein
    Patent number: 8158131
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: April 17, 2012
    Assignee: AltraVax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Novel flavivirus antigens
    Publication number: 20090311287
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: August 30, 2007
    Publication date: December 17, 2009
    Applicant: Maxygen, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Novel Flavivirus antigens
    Publication number: 20090181044
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: March 7, 2008
    Publication date: July 16, 2009
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • antigens
    Patent number: 7476390
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: January 13, 2009
    Assignee: Maxygen, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Novel flavivirus antigens
    Publication number: 20040009469
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: February 26, 2003
    Publication date: January 15, 2004
    Applicant: Maxygen, Inc. Patent Department
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman