Patents by Inventor Alice Roudot

Alice Roudot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRIMARY BILIARY CHOLANGITIS
    Publication number: 20230301951
    Abstract: The invention relates to a pharmaceutical composition comprising elafibranor or a pharmaceutically acceptable salt thereof, for use to treat primary biliary cholangitis (PBC) in a subject intolerant to ursodeoxycholic acid (UDCA).
    Type: Application
    Filed: August 25, 2021
    Publication date: September 28, 2023
    Inventors: Pascal Birman, Alice Roudot, David Magrez, Benoit Noel
  • ELAFIBRANOR FOR THE TREATMENT OF PRIMARY SCLEROSING CHOLANGITIS
    Publication number: 20230165821
    Abstract: The present invention relates to elafibranor or its active metabolite for use in a method for treating primary sclerosing cholangitis.
    Type: Application
    Filed: May 18, 2021
    Publication date: June 1, 2023
    Inventor: Alice Roudot
  • POLYMORPHS OF ELAFIBRANOR
    Publication number: 20230094109
    Abstract: The present invention relates to novel crystalline forms of elafibranor.
    Type: Application
    Filed: February 4, 2021
    Publication date: March 30, 2023
    Inventors: Karine BERTRAND, Jean-François DELHOMEL, Alice ROUDOT
  • ELAFIBRANOR SALTS
    Publication number: 20210309608
    Abstract: The present invention relates to salts of elafibranor.
    Type: Application
    Filed: August 2, 2019
    Publication date: October 7, 2021
    Inventors: Karine BERTRAND, Alice ROUDOT, Marie-Jeanne JOISSAINS
  • Preparation of chalcone derivatives
    Patent number: 8765992
    Abstract: The invention relates to methods for producing chalcone (1,3-diphenylprop-2-en-1-one) derivatives that have multiple substitutions on a phenyl ring. Intermediate chalcone derivatives are modified by Phase Transfer Catalysis (PTC) for introducing a substituted alkyl group that is provided by a sulfonic acid derivative on a phenyl ring already containing substituent groups on one or two carbon atoms adjacent to the carbon atom where a substituent group is being introduced. The methods of the invention allow producing efficiently, by either S-alkylation or O-alkylation, chalcones derivatives that are characterized for their biological activities that are intermediate compounds for producing molecules having such activities, or that can be used for generating libraries of compounds to be screened by means of in vitro and/or in vivo assays and establishing structure-activity relationships.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: July 1, 2014
    Assignee: Genfit
    Inventors: Karine Bertrand, Alice Roudot, Patrice Rool
  • PREPARATION OF CHALCONE DERIVATIVES
    Publication number: 20130131372
    Abstract: The invention relates to methods for producing chalcone (1,3-diphenylprop-2-en-1-one) derivatives that have multiple substitutions on a phenyl ring. Intermediate chalcone derivatives are modified by Phase Transfer Catalysis (PTC) for introducing a substituted alkyl group that is provided by a sulfonic acid derivative on a phenyl ring already containing substituent groups on one or two carbon atoms adjacent to the carbon atom where a substituent group is being introduced. The methods of the invention allow producing efficiently, by either S-alkylation or O-alkylation, chalcones derivatives that are characterized for their biological activities that are intermediate compounds for producing molecules having such activities, or that can be used for generating libraries of compounds to be screened by means of in vitro and/or in vivo assays and establishing structure-activity relationships.
    Type: Application
    Filed: May 16, 2011
    Publication date: May 23, 2013
    Applicant: GENFIT
    Inventors: Karine Bertrand, Alice Roudot, Patrice Rool