Patents by Inventor Aliesha O'Raw

Aliesha O'Raw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Devices, systems, and methods for modulating tissue temperature
    Patent number: 12279990
    Abstract: This present disclosure provides devices, systems, and methods relating to the modulation of tissue temperature. In particular, the present disclosure provides devices, systems, and methods for rapidly cooling or heating tissue in a subject as a therapeutic and/or prophylactic means for treating tissue that has been injured or damaged.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: April 22, 2025
    Assignee: DUKE UNIVERSITY
    Inventors: Rafael Eduardo Chaparro, Paolo Maccarini, Luis Fernando Gonzalez, Donald Pearce, Edward Lysk Wyckoff, III, Syed Faaiz Enam, Jikai Shen, Aliesha O'Raw, Rachel Yang
  • COMPOSITIONS AND METHODS FOR TREATING CANCER-ASSOCIATED CACHEXIA
    Publication number: 20240198099
    Abstract: A method for treating cachexia in a subject in need thereof includes stimulating the parasympathetic nervous system of the subject thereby treating cachexia in the subject. Stimulating the parasympathetic nervous system can increase expression of urea cycle enzymes in the liver of the subject. Parasympathetic nervous system stimulation can comprise stimulating the vagus nerve, for example, the cervical vagus nerve or the hepatic branch of the vagus nerve. Pulses can be delivered at a frequency ranging from 1 Hz to 10 Hz or at a frequency of about 5 KHz.
    Type: Application
    Filed: July 9, 2021
    Publication date: June 20, 2024
    Inventors: Xiling SHEN, Aliesha O'RAW, James MORIZIO, Ashlesha DESHMUKH, Ayelet EREZ, Saar EZAGOURI
  • DEVICES, SYSTEMS, AND METHODS FOR MODULATING TISSUE TEMPERATURE
    Publication number: 20210330490
    Abstract: This present disclosure provides devices, systems, and methods relating to the modulation of tissue temperature. In particular, the present disclosure provides devices, systems, and methods for rapidly cooling or heating tissue in a subject as a therapeutic and/or prophylactic means for treating tissue that has been injured or damaged.
    Type: Application
    Filed: September 6, 2019
    Publication date: October 28, 2021
    Inventors: Rafael Eduardo Chaparro, Paolo Maccarini, Luis Fernando Gonzalez, Donald Pearce, Edward Lysk Wyckoff, III, Syed Faaiz Enam, Jikai Shen, Aliesha O'Raw, Rachel Yang