Patents by Inventor Alim SEIT-NEBI

Alim SEIT-NEBI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101651
    Abstract: The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
    Type: Application
    Filed: December 13, 2023
    Publication date: March 28, 2024
    Inventors: Jingqing ZHANG, Shireen Taleghani YATES, Scott Erik SUNDVOR, Alim SEIT-NEBI
  • Patent number: 11879007
    Abstract: The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and Kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: January 23, 2024
    Assignee: Nima Acquisition, LLC
    Inventors: Jingqing Zhang, Shireen Taleghani Yates, Scott Erik Sundvor, Alim Seit-Nebi
  • Patent number: 11789020
    Abstract: Provided herein are diagnostic methods, devices and kits for detecting neutralizing antibodies to SARS-CoV-2.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: October 17, 2023
    Assignee: Sapphire Biotech, Inc.
    Inventors: Sergei Svarovsky, Douglas Lake, Alim Seit-Nebi, Maria González-Moa
  • Publication number: 20230251256
    Abstract: Molecules, test kits, test kit components and methods for detecting and measuring different first and second antibodies in a test sample using a single test are provided herein. A method includes the steps of obtaining the test specimen from a subject, transferring the test specimen to a sample receiving portion of an assay of a test kit, and reading the results from the assay. The test kit includes a first molecule comprising a first portion of a protein, wherein the first antibody has a first affinity to bind to the first portion, and a second molecule comprising a second portion of the protein different from the first portion, wherein the second antibody has a second affinity to bind to the second portion.
    Type: Application
    Filed: April 5, 2023
    Publication date: August 10, 2023
    Inventors: Alim SEIT-NEBI, Sergei SVAROVSKY
  • Publication number: 20220244258
    Abstract: A method for detection and measurement of neutralizing antibody levels to SARS-CoV-2 in a test-specimen, said method comprising: obtaining a whole blood test-specimen from a subject; transferring the test-specimen to a sample well of a test-cassette, wherein the cassette further comprises a blood filter, a conjugate pad, a nitrocellulose membrane and an absorbent pad, wherein the sample pad comprises ACE2 or a functional fragment thereof, wherein the conjugate pad comprises a viral-ACE2-binding protein coupled to a label; adding a buffer; and reading the results from the test-cassette.
    Type: Application
    Filed: December 16, 2021
    Publication date: August 4, 2022
    Inventors: Sergei Svarovsky, Douglas Lake, Alim Seit-Nebi, Maria González-Moa
  • Publication number: 20220135656
    Abstract: The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and Kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
    Type: Application
    Filed: November 16, 2021
    Publication date: May 5, 2022
    Inventors: Jingqing ZHANG, Shireen Taleghani YATES, Scott Erik SUNDVOR, Alim SEIT-NEBI
  • Patent number: 11214612
    Abstract: The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and Kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: January 4, 2022
    Assignee: Nima Acquisition, LLC
    Inventors: Jingqing Zhang, Shireen Taleghani Yates, Scott Erik Sundvor, Alim Seit-Nebi
  • Publication number: 20210356465
    Abstract: Provided herein are diagnostic methods, devices and kits for detecting neutralizing antibodies to SARS-CoV-2.
    Type: Application
    Filed: May 12, 2021
    Publication date: November 18, 2021
    Inventors: Sergei Svarovsky, Douglas Lake, Alim Seit-Nebi, Maria González-Moa
  • Publication number: 20210214422
    Abstract: The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and Kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
    Type: Application
    Filed: October 12, 2017
    Publication date: July 15, 2021
    Inventors: Jingqing Zhang, Shireen Taleghani Yates, Scott Erik Sundvor, Alim Seit-Nebi
  • Publication number: 20210156860
    Abstract: A method for setting a threshold for basal levels of QSOX1-L in urine comprising: Storing de-identified urine from 100 BC patient samples and from 100 patients with non-malignant conditions; serially diluting the patient samples with a blocking buffer in triplicate followed by incubation in ELISA plates coated with anti-QSOX-L capture Ab; after 1-hour incubation at 37 C, washing plates followed by addition of biotinylated anti-QSOX-L detection antibody; using Streptavidin-HRP to generate dose dependent signal; obtaining a standard curve for each plate using recombinant QSOX1-L protein spiked into urine that has been depleted of QSOX1-L using affinity chromatography column conjugated with anti-sera against 100aa peptide; calculating concentrations of QSOX1-L based on a standard curve for each plate; and calculating a mean concentrations, ±2 SD to establish a reference range for QSOX1-L levels in urine from patients and individuals without malignant disease.
    Type: Application
    Filed: April 6, 2020
    Publication date: May 27, 2021
    Inventors: Sergei SVAROVSKY, Alim SEIT-NEBI, Catalina VALENCIA