Patents by Inventor Alina POPA

Alina POPA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides
    Publication number: 20230346885
    Abstract: The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: December 9, 2022
    Publication date: November 2, 2023
    Inventors: Alex Powlesland, Alfred Lim, Alina Popa, Andrew Brooks, Benjamin Oestringer, Chandramouli Reddy Chillakuri, Christopher Sayer, Dhaval Jaykant Sangani, Elena Galfre, Fiona Chester, Garret Keating, Graham Anthony Hood, Izabela Bombik, Johanne Pentier, Maurits Kleijnen, Meidai Sun, Nicole Mai, Philip Addis, Pietro Dellacristina, Sarah Gilgunn, Victoria Arena De Souza
  • PEPTIDES DERIVED FROM KITA-KYUSHU LUNG CANCER ANTIGEN (KKLC1, CT83, CXORF61) AND COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
    Publication number: 20230330181
    Abstract: The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen 1 (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: January 3, 2023
    Publication date: October 19, 2023
    Inventors: Alex POWLESLAND, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Alina POPA
  • PEPTIDES DERIVED FROM PRORELAXIN H1 (RLN1)
    Publication number: 20210147505
    Abstract: The present invention relates to novel peptides derived from Prorelaxin H1 (RLN1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 16, 2020
    Publication date: May 20, 2021
    Inventors: Alex POWLESLAND, Alina POPA, Meidai SUN
  • PEPTIDES DERIVED FROM ACTIN-LIKE PROTEIN 8 (ACTL8)
    Publication number: 20210145936
    Abstract: The present invention relates to novel peptides derived from Actin-like protein 8 (ACTL8), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: August 19, 2020
    Publication date: May 20, 2021
    Inventors: Alex POWLESLAND, Alina POPA, Philip ADDIS
  • PEPTIDES DERIVED FROM ACHAETE-SCUTE HOMOLOG 2 (ASCL2), COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
    Publication number: 20210122798
    Abstract: The present invention relates to novel peptides derived from Achaete-scute homolog 2 (ASCL2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 16, 2020
    Publication date: April 29, 2021
    Inventors: Alex POWLESLAND, Alina POPA
  • PEPTIDES DERIVED FROM KITA-KYUSHU LUNG CANCER ANTIGEN (KKLC1, CT83, CXORF61) AND COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
    Publication number: 20210121526
    Abstract: The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen 1 (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 29, 2021
    Inventors: Alex POWLESLAND, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Alina POPA
  • PEPTIDES FROM PIWIL1
    Publication number: 20210061857
    Abstract: The present invention relates to novel peptides derived from piwi-like protein 1 (PIWIL1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: August 14, 2020
    Publication date: March 4, 2021
    Inventors: Alex POWLESLAND, Alina POPA, Fiona CHESTER
  • PEPTIDES
    Publication number: 20210054036
    Abstract: The present invention relates to novel peptides derived from Melanoma-associated antigen C1 (MAGEC), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: September 4, 2020
    Publication date: February 25, 2021
    Inventors: Alex POWLESLAND, Alina POPA
  • PEPTIDES DERIVED FROM KALLIKREIN 4
    Publication number: 20210047629
    Abstract: The present invention relates to novel peptides derived from Kallikrein-4 (KLK4), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: August 20, 2020
    Publication date: February 18, 2021
    Inventors: Alex POWLESLAND, Fiona CHESTER, Alina POPA
  • PEPTIDES
    Publication number: 20210017228
    Abstract: The present invention relates to novel peptides derived from DDB1- and CUL4-associated factor 4-like protein 2 (DCAF4L2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: August 7, 2020
    Publication date: January 21, 2021
    Inventors: Alex POWLESLAND, Alina POPA
  • Peptides derived from Kita-kyushu lung cancer antigen (KKLC1, CT83, CXorf61) and complexes comprising such peptides bound to MHC molecules
    Patent number: 10835577
    Abstract: The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: November 17, 2020
    Assignee: IMMUNOCORE LIMITED
    Inventors: Alex Powlesland, Chandramouli Chillakuri, Dhaval Sangani, Graham Hood, Alina Popa
  • Peptides derived from actin-like protein 8 (ACTL8)
    Patent number: 10792333
    Abstract: The present invention relates to novel peptides derived from Actin-like protein 8 (ACTL8), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: October 6, 2020
    Assignee: IMMUNOCORE LIMITED
    Inventors: Alex Powlesland, Alina Popa, Philip Addis
  • PEPTIDES DERIVED FROM ACTIN-LIKE PROTEIN 8 (ACTL8)
    Publication number: 20190038715
    Abstract: The present invention relates to novel peptides derived from Actin-like protein 8 (ACTL8), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: February 7, 2019
    Inventors: Alex POWLESLAND, Alina POPA, Philip ADDIS
  • PEPTIDES
    Publication number: 20180371039
    Abstract: The present invention relates to novel peptides derived from Melanoma-associated antigen C (MAGEC1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 27, 2018
    Inventors: Alex POWLESLAND, Alina POPA
  • PEPTIDES DERIVED FROM ACHAETE-SCUTE HOMOLOG 2 (ASCL2), COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
    Publication number: 20180355006
    Abstract: The present invention relates to novel peptides derived from Achaete-scute homolog 2 (ASCL2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 13, 2018
    Inventors: Alex POWLESLAND, Alina POPA
  • PEPTIDES FROM PIWIL1
    Publication number: 20180346515
    Abstract: The present invention relates to novel peptides derived from piwi-like protein 1 (PIWIL1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 6, 2018
    Inventors: Alex POWLESLAND, Alina POPA, Fiona CHESTER
  • PEPTIDES
    Publication number: 20180346514
    Abstract: The present invention relates to novel peptides derived from DDB1- and CUL4-associated factor 4-like protein 2 (DCAF4L2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 6, 2018
    Inventors: Alex POWLESLAND, Alina POPA
  • PEPTIDES DERIVED FROM PRORELAXIN H1 (RLN1)
    Publication number: 20180340016
    Abstract: The present invention relates to novel peptides derived from Prorelaxin H1 (RLN1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 29, 2018
    Inventors: Alex POWLESLAND, Alina POPA, Meidai SUN
  • PEPTIDES DERIVED FROM KALLIKREIN 4
    Publication number: 20180334663
    Abstract: The present invention relates to novel peptides derived from Kallikrein-4 (KLK4), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 22, 2018
    Inventors: Alex POWLESLAND, Fiona CHESTER, Alina POPA
  • PEPTIDES DERIVED FROM KITA-KYUSHU LUNG CANCER ANTIGEN (KKLC1, CT83, CXORF61) AND COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
    Publication number: 20180326002
    Abstract: The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 15, 2018
    Inventors: Alex POWLESLAND, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Alina POPA