Patents by Inventor Aline Thomas

Aline Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR THE TREATMENT OF HEMOPHILIA
    Publication number: 20230346727
    Abstract: A compound of general formula (III?), or one of its pharmaceutically acceptable salts, for its use for the treatment of hemophilia in a subject, in particular for the restoration of coagulation in the plasma of a subject suffering from hemophilia, this compound being advantageously administered by oral route:
    Type: Application
    Filed: July 23, 2021
    Publication date: November 2, 2023
    Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Aline THOMAS, Marie-Claire DAGHER, Muriel JOURDAN, Romain NAVARRO, Benoît POLACK, Raphaël MARLU, Landry SEYVE, Renaud ZELLI
  • Procoagulant molecular decoy for treating hemophilia A or B with or without inhibitor
    Patent number: 9493761
    Abstract: The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: November 15, 2016
    Assignees: UNIVERSITE JOSEPH FOURIER (GRENOBLE 1), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Benoit Polack, Aline Thomas
  • GLA-DOMAINLESS FACTOR X
    Publication number: 20160177286
    Abstract: The present invention relates to a protein consisting of the sequence SEQ ID No.: 11 or 25 or 26, directly bound, or bound via a linker, especially -Arg-Lys-Arg-, to the sequence SEQ ID No.: 6.
    Type: Application
    Filed: June 20, 2014
    Publication date: June 23, 2016
    Applicants: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS, UNIVERSITE GRENOBLE I JOSEPH FOURIER
    Inventors: Aline Thomas, Marie-Claire Dagher, Raphael Marlu, Benoit Polack, Jean-Luc Plantier, Alexandre Fontayne, Toufik Abache
  • NOVEL PROCOAGULANT MOLECULAR DECOY FOR TREATING HEMOPHILIA A OR B WITH OR WITHOUT INHIBITOR
    Publication number: 20140050716
    Abstract: The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.
    Type: Application
    Filed: February 29, 2012
    Publication date: February 20, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIER (GRENOBLE 1)
    Inventors: Benoit Polack, Aline Thomas
  • SPRAYING DEVICE AND METHOD
    Publication number: 20120058264
    Abstract: The present invention relates to a spraying nozzle, a spraying device including such a nozzle, and a spraying method implementing such a device. A nozzle for projecting powdery sold products for coating objects. The nozzle comprises a body having an essentially cylindrical shape and comprises at least two tunnels extending there through and insulated from each other. Each tunnel developing helically about a main axis of the nozzle. The tunnels are independently supplied with a fluid/powdery solid(s) mixture. The helical shape of the tunnels makes it possible to obtain a powerful jet with a conical shape capable of coating the inner surfaces of tubular objects.
    Type: Application
    Filed: April 22, 2010
    Publication date: March 8, 2012
    Inventors: Gregory Filou, Denis Huze, Aline Thomas