Patents by Inventor Alisa Berlin

Alisa Berlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7687652
    Abstract: Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: March 30, 2010
    Assignee: Biolab Ltd
    Inventors: Elimelech Rochlin, Jean Hildesheim, Alisa Berlin
  • Patent number: 7361756
    Abstract: The invention encompasses synthesizing 7-(4-bromobutoxy)-3,4-dihydrocarbostyril by mixing 7-hydroxy-tetrahydroquinolinone, dibromobutane, and at least one base to form a reaction mixture; heating the reaction mixture; cooling the reaction mixture; and isolating the 7-(4-bromobutoxy)-3,4-dihydrocarbostyril from the reaction mixture. The invention also encompasses using phase transfer catalysts during the reaction.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: April 22, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ben-Zion Dolitzky, Jean Hildesheim, Alisa Berlin
  • Publication number: 20070282120
    Abstract: Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.
    Type: Application
    Filed: January 13, 2005
    Publication date: December 6, 2007
    Inventors: Elimelech Rochlin, Jean Hildesheim, Alisa Berlin
  • Publication number: 20050215585
    Abstract: The invention encompasses synthesizing 7-(4-bromobutoxy)-3,4-dihydrocarbostyril by mixing 7-hydroxy-tetrahydroquinolinone, dibromobutane, and at least one base to form a reaction mixture; heating the reaction mixture; cooling the reaction mixture; and isolating the 7-(4-bromobutoxy)-3,4-dihydrocarbostyril from the reaction mixture. The invention also encompasses using phase transfer catalysts during the reaction.
    Type: Application
    Filed: February 7, 2005
    Publication date: September 29, 2005
    Inventors: Ben-Zion Dolitzky, Jean Hildesheim, Alisa Berlin