Patents by Inventor Alisha Gruntman

Alisha Gruntman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PERFUSION-BASED DELIVERY OF RECOMBINANT AAV VECTORS FOR EXPRESSION OF SECRETED PROTEINS
    Publication number: 20210393805
    Abstract: In some aspects, the disclosure relates to methods and compositions for delivering a transgene to a subject. The disclosure is based, in part, on compositions (e.g., viral vectors, such as rAAV vectors) and methods of venous limb perfusion (VLP) that efficiently transduce muscle tissue and enhance serum concentrations of secreted transgenes.
    Type: Application
    Filed: May 16, 2019
    Publication date: December 23, 2021
    Applicant: University of Massachusetts
    Inventors: Alisha Gruntman, Terence Flotte