Patents by Inventor Alison J. Scott

Alison J. Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING SEPSIS USING ANTI-SEPSIS LIPID A (ASLA) BASED THERAPEUTICS
    Publication number: 20230241084
    Abstract: The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein R1 and R2 may be H, OH, protonated phosphate, a phosphate salt, a sugar phosphonate, or a mono-, di- or poly-saccharide, R3 may be OH or a mono-, di- or poly-saccharide, R4, R5, R6 and R7 may be an alkyl or alkenyl chain of up to 13 carbons (for a chain of 16 carbons), and R8, R9, R10 and R11 may be H, OH, or an alkyl or alkenyl ester of up to 16 carbons, or a salt thereof.
    Type: Application
    Filed: December 21, 2022
    Publication date: August 3, 2023
    Inventors: Robert K. Ernst, Erin M. Harberts, Alison J. Scott
  • Methods of treating sepsis using anti-sepsis lipid A (ASLA) based therapeutics
    Patent number: 11633411
    Abstract: The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein R1 and R2 may be H, OH, protonated phosphate, a phosphate salt, a sugar phosphonate, or a mono-, di- or poly-saccharide, R3 may be OH or a mono-, di- or poly-saccharide, R4, R5, R6 and R7 may be an alkyl or alkenyl chain of up to 13 carbons (for a chain of 16 carbons), and R8, R9, R10 and R11 may be H, OH, or an alkyl or alkenyl ester of up to 16 carbons, or a salt thereof.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: April 25, 2023
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Robert K. Ernst, Erin M. Harberts, Alison J. Scott
  • METHODS OF TREATING SEPSIS USING ANTI-SEPSIS LIPID A (ASLA) BASED THERAPEUTICS
    Publication number: 20200121705
    Abstract: The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein R1 and R2 may be H, OH, protonated phosphate, a phosphate salt, a sugar phosphonate, or a mono-, di- or poly-saccharide, R3 may be OH or a mono-, di- or poly-saccharide, R4, R5, R6 and R7 may be an alkyl or alkenyl chain of up to 13 carbons (for a chain of 16 carbons), and R8, R9, R10 and R11 may be H, OH, or an alkyl or alkenyl ester of up to 16 carbons, or a salt thereof.
    Type: Application
    Filed: October 4, 2017
    Publication date: April 23, 2020
    Applicant: University of Maryland, Baltimore
    Inventors: Robert K. Ernst, Erin M. Harberts, Alison J. Scott
  • Immunogenic compositions comprising nanoemulsion and hepatitis B virus immunogen and methods of using the same
    Patent number: 9415006
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides immunogenic compositions and methods of using the same to induce immune responses (e.g., immunity (e.g., protective immunity)) against Hepatitis B virus (HBV)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
    Type: Grant
    Filed: May 26, 2009
    Date of Patent: August 16, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James R. Baker, Jr., Anna U. Bielinska, Nicholas Mank, Paul E. Makidon, Zhengyi Cao, Alison J Scott, Shraddha S. Nigavekar
  • IMMUNOGENIC COMPOSITIONS COMPRISING NANOEMULSION AND HEPATITIS B VIRUS IMMUNOGEN AND METHODS OF USING THE SAME
    Publication number: 20100028433
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides immunogenic compositions and methods of using the same to induce immune responses (e.g., immunity (e.g., protective immunity)) against Hepatitis B virus (HBV)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
    Type: Application
    Filed: May 26, 2009
    Publication date: February 4, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James R. Baker, JR., Anna U. Bielinska, Nicholas J. Mank, Paul E. Makidon, Zhengyi Cao, Alison J. Scott, Shraddha S. Nigavekar