Patents by Inventor Alison Jayne Foster
Alison Jayne Foster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9718036Abstract: The invention provides a method for the preparation of a carrier liquid which comprises the steps of: (I) preparing a single phase solution comprising: (a) a solvent or a mixture of miscible solvents, (b) a liquid carrier material, which is soluble in solvent (a), and (c) a dopant material which is also soluble in solvent (a); (II) cooling (preferably freezing) the single phase solution produced in step (I) to a temperature at which at least both the solvent (a) and carrier material (b) become solid; and (III) removing solid solvent (a) from the cooled (frozen) single phase solution in vapor form, such that the remaining cooled (frozen) carrier material (b) and dopant material (c) are returned to ambient temperature thus providing a product of liquid carrier material (b) having dopant material (c) dispersed therein.Type: GrantFiled: August 20, 2012Date of Patent: August 1, 2017Assignee: The University of LiverpoolInventors: Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20170112125Abstract: The invention provides a method for preparing an improved composition comprising at least one active agent and at least one solid carrier material, wherein the active agent is dispersed through the carrier material in nano-disperse form, which method comprises the steps of: (a) forming a liquid mixture comprising the active agent, the carrier material, a stabilizing agent, a first solvent for the active agent and the stabilizing agent and, a second solvent for the carrier material, and (b) drying the liquid mixture to remove the first and second solvents to obtain a substantially solvent-free nano-dispersion of the active agent with the stabilising agent in the carrier material, wherein the stabilizing agent is capable of stabilizing the active agent in the liquid mixture during drying and in a resultant liquid nano-dispersion of the improved composition.Type: ApplicationFiled: September 30, 2016Publication date: April 27, 2017Inventors: Steven Paul Rannard, David Duncalf, Alison Jayne Foster, James Long, Dong Wang
-
Patent number: 9060937Abstract: A process for the production of a composition comprising a water-insoluble sartan which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble sartan, ii) a water soluble carrier, iii) a solvent for each of the sartan and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the sartan in the carrier.Type: GrantFiled: June 29, 2007Date of Patent: June 23, 2015Inventors: David John Duncalf, Andrew James Elphick, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Patent number: 8945626Abstract: A process for the production of a composition comprising a water-insoluble paracetamol or NSAID which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble paracetamol or NSAID, ii) a water soluble carrier, and iii) a solvent for each of the paracetamol or NSAID and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the paracetamol or NSAID in the carrier.Type: GrantFiled: July 13, 2007Date of Patent: February 3, 2015Inventors: Andrew James Elphick, John Staniforth, Dong Wang, David John Duncalf, Steven Paul Rannard, James Long, Alison Jayne Foster
-
Patent number: 8821932Abstract: A process for the production of a composition comprising a water-insoluble statin which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble statin ii) a water soluble carrier, iii) a solvent for each of the statin and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the statin in the carrier.Type: GrantFiled: June 29, 2007Date of Patent: September 2, 2014Inventors: David John Duncalf, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20140212466Abstract: The invention provides a method for the preparation of a carrier liquid which comprises the steps of: (I) preparing a single phase solution comprising: (a) a solvent or a mixture of miscible solvents, (b) a liquid carrier material, which is soluble in solvent (a), and (c) a dopant material which is also soluble in solvent (a); (II) cooling (preferably freezing) the single phase solution produced in step (I) to a temperature at which at least both the solvent (a) and carrier material (b) become solid; and (III) removing solid solvent (a) from the cooled (frozen) single phase solution in vapour form, such that the remaining cooled (frozen) carrier material (b) and dopant material (c) are returned to ambient temperature thus providing a product of liquid carrier material (b) having dopant material (c) dispersed therein.Type: ApplicationFiled: August 20, 2012Publication date: July 31, 2014Applicant: IOTA NANOSOLUTIONS LIMITEDInventors: Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20130196852Abstract: The invention provides a method for preparing an improved composition comprising at least one active agent and at least one solid carrier material, wherein the active agent is dispersed through the carrier material in nano-disperse form, which method comprises the steps of: (a) forming a liquid mixture comprising the active agent, the carrier material, a stabilizing agent, a first solvent for the active agent and the stabilizing agent and, a second solvent for the carrier material, and (b) drying the liquid mixture to remove the first and second solvents to obtain a substantially solvent-free nano-dispersion of the active agent with the stabilising agent in the carrier material, wherein the stabilizing agent is capable of stabilizing the active agent in the liquid mixture during drying and in a resultant liquid nano-dispersion of the improved composition.Type: ApplicationFiled: October 4, 2011Publication date: August 1, 2013Applicant: IOTA NANOSOLUTIONS LIMITEDInventors: Steven Paul Rannard, David Duncalf, Alison Jayne Foster, James Long, Dong Wang
-
Patent number: 8242182Abstract: The invention provides a method for preparing water dispersible or water soluble porous bodies and the bodies themselves The bodies have an intrusion volume as measured by mercury porosimetry of at least about 3 ml/g and comprise a three dimensional open-cell lattice containing less than 10% by weight of a water soluble polymeric material and 5 to 90% by weight of a surfactant, with the proviso that said porous bodies are not spherical beads having an average bead diameter of 0.2 to 5 mm.Type: GrantFiled: January 28, 2005Date of Patent: August 14, 2012Assignee: IOTA NanoSolutions LimitedInventors: Andrew Ian Cooper, David John Duncalf, Alison Jayne Foster, Steven Paul Rannard, Haifei Zhang
-
Publication number: 20120135058Abstract: The invention provides process for making contra-soluble nano-dispersions of at most sparingly-soluble materials in a soluble carrier material comprising the steps of: (i) providing a single phase mixture of: (a) a solvent or a mixture of miscible solvents wherein at least one of the solvents is an aqueous solvent and at least another solvent is a non-aqueous solvent, (b) at least one carrier material soluble in solvent (a), said carrier material being also contra-soluble to payload material (c) and solid at ambient temperature, (c) at least one a payload material which is soluble in solvent (a), and, (ii) freeze-drying the mixture to remove solvent (a) and thereby obtain the carrier material (b) in solid form with payload (c) dispersed therein as nanoparticles.Type: ApplicationFiled: February 3, 2012Publication date: May 31, 2012Applicant: IOTA NanoSolutions LimitedInventors: Doris Angus, David John Duncalf, Andrew James Elphick, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20120134940Abstract: The invention provides process for making water-soluble nano-dispersions of water-insoluble materials in a water-soluble carrier material comprising the steps of: (i) providing a single phase mixture of: (a) a non-aqueous solvent or a mixture of miscible non-aqueous solvents, (b) at least one carrier material soluble in non-aqueous solvent (a), said carrier material being also soluble in water and solid at ambient temperature, (c) at least one water-insoluble payload material which is soluble in non-solvent (a), and, (ii) drying the mixture to remove solvent (a) and thereby obtain the carrier material (b) in solid form with payload (c) dispersed therein as nanoparticles, wherein the product of the drying step is water dispersible to give an aqueous solution of (b) and an aqueous nano-dispersion of (c).Type: ApplicationFiled: February 3, 2012Publication date: May 31, 2012Applicant: IOTA NanoSolutions LimitedInventors: Doris Angus, David John Duncalf, Andrew James Elphick, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20110217340Abstract: A process for the production of a soluble composition comprising a water-insoluble active which comprises either the steps of: a) providing a liquid mixture comprising: i) a dissolved water-insoluble active, ii) a dissolved water-soluble carrier, iii) a solvent for each of the active and the carrier, and b) spray-granulating the mixture to remove the, or each, solvent and obtain a substantially solvent-free nano-dispersion of the water-insoluble active in the carrier said water-insoluble active being in nano-particles having a size range of 999-20 nm; or, the steps of: a) providing a substantially solvent-free powder comprising a water-insoluble active dispersed in a water soluble carrier, said water-insoluble active being in nano-particles having a size range of 999-20 nm, and, b) spray-granulating the powder to obtain larger and denser particles. The invention also relates to solvent-free, granular products with a particle size in the range 20 microns to 10 mm and a bulk-density of greater than 0.Type: ApplicationFiled: July 24, 2009Publication date: September 8, 2011Inventors: Doris Angus, Alison Jayne Foster, David Duncalf, Steven Paul Rannard, Dong Wang
-
Patent number: 7985423Abstract: Porous bodies which are soluble or dispersible in non-aqueous media comprising a three dimensional open-cell lattice containing (a) 10 to 70% by weight of a polymeric material which is soluble in water immiscible non-aqueous media and (b) 30 to 90% by weight of a surfactant, said porous bodies having an intrusion volume as measured by mercury porosimetry of at least 3 ml/g.Type: GrantFiled: December 23, 2004Date of Patent: July 26, 2011Assignee: IOTA NanoSolutions LimitedInventors: Andrew Ian Cooper, Alison Jayne Foster, Steven Paul Rannard, Haifei Zhang
-
Patent number: 7691873Abstract: A process for the production of a composition comprising a water-insoluble opioid which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble opioid, ii) a water soluble carrier, and iii) a solvent for each of the opioid and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the opioid in the carrier.Type: GrantFiled: July 13, 2007Date of Patent: April 6, 2010Assignee: Conopco, Inc.Inventors: David John Duncalf, Steven Paul Rannard, James Long, Dong Wang, Andrew James Elphick, John Staniforth, Daniele Chauvin, Alison Jayne Foster
-
Publication number: 20100015229Abstract: A process for the production of a composition comprising a water-insoluble statin which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble statin ii) a water soluble carrier, iii) a solvent for each of the statin and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the statin in the carrier.Type: ApplicationFiled: June 29, 2007Publication date: January 21, 2010Inventors: David John Duncalf, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20100015233Abstract: The present invention relates to nanodisperse antiparasitics and provides a composition comprising at least one water insoluble anti-parasitic drug and a water-soluble carrier material, wherein the water-insoluble anti-parasitic drug (preferably an Artemisinin-type drug or a quinine type drug) is dispersed through the carrier material in nano-disperse form having a peak diameter of the nano-disperse form below 1000 nm.Type: ApplicationFiled: June 29, 2007Publication date: January 21, 2010Inventors: David John Duncalf, Asha Hassan Essa, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Publication number: 20100008995Abstract: A process for the production of a composition comprising a water-insoluble triptan which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble triptan, ii) a water soluble carrier, and iii) a solvent for each of the triptan and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the triptan in the carrier.Type: ApplicationFiled: July 13, 2007Publication date: January 14, 2010Inventors: David John Duncalf, Paul Rannard, James Long, Dong Wang, Andrew James Elphick, John Staniforth, Alison Jayne Foster
-
Publication number: 20090325995Abstract: A process for the production of a composition comprising a water-insoluble opioid which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble opioid, ii) a water soluble carrier, and iii) a solvent for each of the opioid and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the opioid in the carrierType: ApplicationFiled: July 13, 2007Publication date: December 31, 2009Inventors: David John Duncalf, Steven Paul Rannard, James Long, Dong Wang, Andrew James Elphick, John Staniforth, Daniele Chauvin, Alison Jayne Foster
-
Publication number: 20090304806Abstract: A process for the production of a composition comprising a water-insoluble sartan which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble sartan, ii) a water soluble carrier, iii) a solvent for each of the sartan and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the sartan in the carrier.Type: ApplicationFiled: June 29, 2007Publication date: December 10, 2009Inventors: David John Duncalf, Andrew James Elphick, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang
-
Patent number: 7615560Abstract: Use of a compound of formula (I) where R1 is a C4-6 alkylene linkage optionally substituted by a C1-4alkyl group; R2 is ?NH, —NH2 or —OH; R3 is C1-5 alkyl optionally terminated by a hydroxy, phenyl or a 5- or 6-membered heterocyclic group such as furyl or N-imidazolyl and R4 is H; or R3 and R4 together form a C3-5 alkylene linkage; to produce a topical refreshing or cooling sensation in a mammal such as a human.Type: GrantFiled: November 7, 2005Date of Patent: November 10, 2009Assignee: Conopco, Inc.Inventors: Alison Jayne Foster, Cornelis Paul Erik van der Logt, Afrodite Lourbakos, Erwin Werner Tareilus
-
Publication number: 20090239749Abstract: The invention provides a solvent-free biocidal composition of improved efficacy comprising at least one water insoluble biocide (preferably a herbicide) and a water-soluble carrier material, wherein the water-insoluble biocide is dispersed through the carrier material in nano-disperse form having a peak diameter of the nano-disperse form below 1000 nm. The invention also provides a process which comprises spray drying a solution of the biocide and a solution of a water-soluble carrier to obtain a solvent free dispersion of the biocide in the carrier, which, when dissolved in water, produces a nano-disperse biocide. The invention also provides an aqueous dispersion of a water insoluble biocide and a water-soluble carrier obtained by the dispersion of the composition of the solvent free composition in water.Type: ApplicationFiled: June 29, 2007Publication date: September 24, 2009Inventors: David John Duncalf, Alison Jayne Foster, James Long, Steven Paul Rannard, Dong Wang