Patents by Inventor Alison M. Skelley

Alison M. Skelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Particle capture devices and methods of use thereof
    Patent number: 9201060
    Abstract: The present invention provides a device and methods of use thereof in microscale particle capturing and particle pairing. This invention provides particle patterning device, which mechanically traps individual particles within first chambers of capture units, transfer the particles to second chambers of opposing capture units, and traps a second type of particle in the same second chamber. The device and methods allow for high yield assaying of trapped cells, high yield fusion of trapped, paired cells, for controlled binding of particles to cells and for specific chemical reactions between particle interfaces and particle contents. The device and method provide means of identification of the particle population and a facile route to particle collection.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: December 1, 2015
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Joel Voldman, Alison M. Skelley, Oktay Kirak, Rudolf Jaenisch
  • PARTICLE CAPTURE DEVICES AND METHODS OF USE THEREOF
    Publication number: 20110045994
    Abstract: The present invention provides a device and methods of use thereof in microscale particle capturing and particle pairing. This invention provides particle patterning device, which mechanically traps individual particles within first chambers of capture units, transfer the particles to second chambers of opposing capture units, and traps a second type of particle in the same second chamber. The device and methods allow for high yield assaying of trapped cells, high yield fusion of trapped, paired cells, for controlled binding of particles to cells and for specific chemical reactions between particle interfaces and particle contents. The device and method provide means of identification of the particle population and a facile route to particle collection.
    Type: Application
    Filed: February 11, 2009
    Publication date: February 24, 2011
    Inventors: Joel Voldman, Alison M. Skelley, Oktay Kirak, Rudolf Jaenisch