Patents by Inventor Alison McDermott

Alison McDermott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Esculentin 1a derivatives and uses thereof
    Patent number: 11110195
    Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: September 7, 2021
    Assignees: UNIVERSITY OF HOUSTON SYSTEM, UNIVERSITA' DEGLI STUDI DI ROMA LA SAPIENZA
    Inventors: Alison McDermott, Maria Luisa Mangoni
  • ESCULENTIN 1a DERIVATIVES AND USES THEREOF
    Publication number: 20200324014
    Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 15, 2020
    Applicants: University of Houston System, Universita' degli Studi di Roma La Sapienza
    Inventors: Alison McDermott, Maria Luisa Mangoni
  • Esculentin 1a derivatives and uses thereof
    Patent number: 10751440
    Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
    Type: Grant
    Filed: August 26, 2018
    Date of Patent: August 25, 2020
    Assignees: UNIVERSITY OF HOUSTON SYSTEM, UNIVERSITA' DEGLI STUDI DI ROMA LA SAPIENZA
    Inventors: Alison McDermott, Maria Luisa Mangoni
  • Esculentin 1a Derivatives and Uses Thereof
    Publication number: 20180361010
    Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
    Type: Application
    Filed: August 26, 2018
    Publication date: December 20, 2018
    Applicants: University of Houston System, Universita' degli Studi di Roma La Sapienza
    Inventors: Alison McDermott, Marialuisa Mangoni
  • Esculentin 1a derivatives and uses thereof
    Patent number: 10059752
    Abstract: The present invention provides synthetic antibacterial peptides comprising a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for reducing the severity of microbe-induced inflammation and for stimulating wound healing via the synthetic antibacterial peptides. Further provided is a device having a surface with a coating comprising the synthetic antibacterial peptides.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: August 28, 2018
    Assignees: University of Houston System, Universita' Degli Studi Di Roma La Sapienza
    Inventors: Alison McDermott, Marialuisa Mangoni
  • Esculentin 1a Derivatives and Uses Thereof
    Publication number: 20150104492
    Abstract: The present invention provides synthetic antibacterial peptides comprising a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for reducing the severity of microbe-induced inflammation and for stimulating wound healing via the synthetic antibacterial peptides. Further provided is a device having a surface with a coating comprising the synthetic antibacterial peptides.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 16, 2015
    Inventors: Alison McDermott, Marialuisa Mangoni