Patents by Inventor Alison Sismey-Ragatz

Alison Sismey-Ragatz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of Defined Monodisperse Heparosan Polymers and Unnatural Polymers with Polysaccharide Synthases
    Publication number: 20160053290
    Abstract: A methodology for polymer grafting by a polysaccharide synthase allows the creation of a variety of glycosaminoglycan oligosaccharides that may have a natural, chimeric, hybrid, and/or unnatural sugar structure and/or a targeted size (i.e., substantially monodisperse in size).
    Type: Application
    Filed: November 10, 2015
    Publication date: February 25, 2016
    Inventors: Paul L. DEANGELIS, Alison SISMEY-RAGATZ
  • Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
    Patent number: 9200024
    Abstract: A methodology for polymer grafting by a polysaccharide synthase allows the creation of a variety of glycosaminoglycan oligosaccharides that have a natural, chimeric, hybrid and/or unnatural sugar structure and/or a targeted size (i.e., substantially monodisperse in size).
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: December 1, 2015
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Alison Sismey-Ragatz
  • PRODUCTION OF DEFINED MONODISPERSE HEPAROSAN POLYMERS AND UNNATURAL POLYMERS WITH POLYSACCHARIDE SYNTHASES
    Publication number: 20120108802
    Abstract: A methodology for polymer grafting by a polysaccharide synthase allows the creation of a variety of glycosaminoglycan oligosaccharides that have a natural, chimeric, hybrid and/or unnatural sugar structure and/or a targeted size (i.e., substantially monodisperse in size).
    Type: Application
    Filed: December 14, 2011
    Publication date: May 3, 2012
    Inventors: Paul L. DeAngelis, Alison Sismey-Ragatz
  • Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
    Patent number: 8088604
    Abstract: The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size. The present invention also relates to methodology for polymer grafting by a polysaccharide synthase to form glycosaminoglycan polymers having an unnatural structure.
    Type: Grant
    Filed: October 3, 2007
    Date of Patent: January 3, 2012
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Alison Sismey-Ragatz
  • Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
    Publication number: 20080109236
    Abstract: The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size. The present invention also relates to methodology for polymer grafting by a polysaccharide synthase to form glycosaminoglycan polymers having an unnatural structure.
    Type: Application
    Filed: October 3, 2007
    Publication date: May 8, 2008
    Inventors: Paul DeAngelis, Alison Sismey-Ragatz
  • Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
    Publication number: 20080108110
    Abstract: The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size. The present invention also relates to methodology for polymer grafting by a polysachharide synthase to form glycosaminoglycan polymers having an unnatural structure.
    Type: Application
    Filed: October 3, 2007
    Publication date: May 8, 2008
    Inventors: Paul DeAngelis, Alison Sismey-Ragatz