Patents by Inventor Alison Taunton-Rigby

Alison Taunton-Rigby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA means and method for producing rennin, prorenin and pre-prorennin
    Patent number: 5525484
    Abstract: Living cells containing genetic material derived from recombinant DNA material and capable of expressing rennin, pre-prorennin and prorennin. The rennin, pre-prorennin and prorennin are derived from cells which are themselves or have had parents thereof treated by recombinant DNA methods to allow production of the desired enzymatic proteins during growth in culture.
    Type: Grant
    Filed: June 5, 1987
    Date of Patent: June 11, 1996
    Assignee: Genome Therapeutics Corp.
    Inventors: Bernadette L. Alford, Jen-I Mao, Donald T. Moir, Alison Taunton-Rigby, Gerald F. Vovis
  • Processes for producing pre-prorennin, prorennin and rennin
    Patent number: 5496711
    Abstract: Living cells containing genetic material derived from recombinant DNA material and capable of expressing rennin, pre-prorennin and prorennin. The rennin, pre-prorennin and prorennin are derived from cells which are themselves or have had parents thereof treated by recombinant DNA methods to allow production of the desired enzymatic proteins during growth in culture.
    Type: Grant
    Filed: July 12, 1989
    Date of Patent: March 5, 1996
    Assignee: Genome Therapeutics Corp.
    Inventors: Bernadette L. Alford, Jen-I Mao, Donald T. Moir, Alison Taunton-Rigby, Gerald F. Vovis
  • Use of the GAL1 yeast promoter
    Patent number: 5139936
    Abstract: A DNA segment contains a GAL1 promoter of Saccharomyces cerevisae linked to a gene other than the galoctokinase gene, for directing the expression of the gene within a yeast cell.A GAL1 promoter portion of Saccharomyces cerevisae is linked to a foreign DNA segment for use in expressing a desired protein. Yeast cells containing the GAL1 promoter linked to a foreign DNA segment are grown in a medium containing glucose, wherein the yeast cells metabolize the glucose and are permitted to express a polypeptide when galactose is present in the medium.
    Type: Grant
    Filed: December 13, 1988
    Date of Patent: August 18, 1992
    Assignee: Collaborative Research, Inc.
    Inventors: David Botstein, Ronald W. Davis, Gerald R. Fink, Alison Taunton-Rigby, Robert G. Knowlton, Jen-i Mao, Donald T. Moir, Christopher G. Goff
  • Recombinant DNA means and method
    Patent number: 4666847
    Abstract: Living cells containing genetic material derived from recombinant DNA material and capable of expressing rennin, pre-prorennin and prorennin. The rennin, pre-prorennin and prorennin are derived from cells which are themselves or have had parents thereof treated by recombinant DNA methods to allow production of the desired enzymatic proteins during growth in culture.
    Type: Grant
    Filed: December 1, 1981
    Date of Patent: May 19, 1987
    Assignee: Collaborative Research, Inc.
    Inventors: Bernadette L. Alford, Jen-I Mao, Donald T. Moir, Alison Taunton-Rigby, Gerald F. Vovis
  • GAL1 yeast promoter linked to non galactokinase gene
    Patent number: 4661454
    Abstract: A DNA segment containing a GAL1 promoter linked to a gene other than the galactokinase gene for directing the expression of the gene within a yeast cell.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: April 28, 1987
    Assignee: Collaborative Research, Inc.
    Inventors: David Botstein, Ronald W. Davis, Gerald R. Fink, Alison Taunton-Rigby, Robert G. Knowlton, Jen-i Mao, Donald T. Moir, Christopher G. Goff
  • Production of N.sup.5 -methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid
    Patent number: 3983118
    Abstract: The preparation of N.sup.5 -methyltetrahydrohomofolic acid and alkali metal salts thereof is from homofolic acid starting material (HFA) by catalytic reduction with platinum oxide in the dark under hydrogen at a slight overpressure to produce tetrahydrohomofolate (THHF), them immediately reacting this product with formaldehyde to produce 5,11-methylenetetrahydrohomofolate and reducing this methylene intermediate without isolation with sodium borohydride to give the desired 5-methyltetrahydrohomofolate in the disodium salt form. The 5-methyl product is recovered by precipitating side products at a pH of about 3.8 with acetic acid and refrigerating the product filtrate overnight at about 3.degree.-10.degree.C. The filtrate containing the product 5-methyltetrahydrohomofolate (5-MeTHHF) is treated with charcoal, concentrated to an oil and the 5-methyl product is precipitated with absolute ethanol.
    Type: Grant
    Filed: August 16, 1974
    Date of Patent: September 28, 1976
    Assignee: The United States of America as represented by the Department of Health, Education and Welfare
    Inventors: Roger L. Knott, Alison Taunton-Rigby, John A. R. Mead