Abstract: The invention relates to compounds capable of modulating the permeability of junctions between epithelial cells, and their use to facilitate delivery of substances such as therapeutic and diagnostic agents across epithelial surfaces.

Abstract: A shield for overlying a keypad such as a PIN pad. The shield 10 permits manual access to the pad 24 and comprised a screen 30 having a transverse direction and a longitudinal direction and formed from a transparent material through which in use the keypad is viewable by a user of the keypad only from within a limited angular range. The screen has an upper side 44 directed in use generally toward a user and a lower side 41 directed in use generally toward the keypad, the screen further having an upper series of transversely extending parallel opaque strips 45 and transparent gaps, and a similar lower series of strips 40 and gaps, which lower series is offset from the upper series so that, when viewed from above, the opaque strips of the upper and lower series overlap and block the view.

Abstract: A shield for overlying a keypad such as a PIN pad. The shield 10 permits manual access to the pad 24 and comprised a screen 30 having a transverse direction and a longitudinal direction and formed from a transparent material through which in use the keypad is viewable by a user of the keypad only from within a limited angular range. The screen has an upper side 44 directed in use generally toward a user and a lower side 41 directed in use generally toward the keypad, the screen further having an upper series of transversely extending parallel opaque strips 45 and transparent gaps, and a similar lower series of strips 40 and gaps, which lower series is offset from the upper series so that, when viewed from above, the opaque strips of the upper and lower series overlap and block the view.

Abstract: The present invention provides a shield for overlying a keypad and restricting the view of third parties. The shield comprises a main body connectable to the keypad and a screen defined in the main body and overlying the keypad. The keypad may only be viewed through the screen by the user of the keypad. The screen may be slidable and may be provided with a film that restricts the viewing angle such that the keypad may only be viewed through the screen from within a range of angles, which range is approximately 20° centered normal to the surface of the screen. The main body further provides an opening through which manual access to the keypad is permitted. The present invention finds particular use on the keypad of ATMs and point of sale PIN units.