Patents by Inventor Alistair Wheeler

Alistair Wheeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of reducing basophil levels
    Patent number: 9815895
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: November 14, 2017
    Assignees: BIOWA, INC., ASTRAZENECA AB
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • Methods Of Reducing Eosinophil Levels
    Publication number: 20140004109
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 2, 2014
    Applicants: Medlmmune, LLC, Biowa, Inc.
    Inventors: Masamichi Koike, George L. SPITALNY, Alistair WHEELER, Barbara WHITE
  • Methods of reducing eosinophil levels
    Patent number: 8501176
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: August 6, 2013
    Assignees: MedImmune, LLC, BIOWA, Inc.
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • Methods Of Reducing Eosinophil Levels
    Publication number: 20120148575
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: July 6, 2011
    Publication date: June 14, 2012
    Applicants: BIOWA, INC., Medlmmune, LLC
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • METHODS OF REDUCING EOSINOPHIL LEVELS
    Publication number: 20100291073
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e g, esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: May 14, 2008
    Publication date: November 18, 2010
    Applicants: MEDIMMUNE, LLC, BIOWA, INC.
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White