Patents by Inventor Alka Marwaha

Alka Marwaha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase
    Patent number: 9238653
    Abstract: Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: January 19, 2016
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, MMV MEDICINES FOR MALARIA VENTURE, UNIVERSITY OF WASHINGTON
    Inventors: Pradipsinh K. Rathod, David Floyd, Jeremy Burrows, Alka Marwaha, Ramesh Gujjar, Jose Coteron-Lopez, Margaret Phillips, Susan A. Charman, David Matthews
  • Dihydroorotate dehydrogenase inhibitors with selective anti-malarial activity
    Patent number: 9216983
    Abstract: Compounds according to Formula I, Formula II, Formula III, Formula V, Formula VI, or to Formula VII, and pharmaceutical compositions of compounds that conform to Formula IV or Formula VIII: where R1 through R33 are prescribed, selectively inhibit P. falciparum dihydroorotate dehydrogenase. Accordingly, a method for preventing and treating malaria attaches to such compounds, as well as to pharmaceutically acceptable salts, solvates, stereoisomers, tautomers, and prodrugs thereof.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: December 22, 2015
    Assignees: BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM, UNIVERSITY OF WASHINGTON, MONASH UNIVERSITY
    Inventors: Margaret Phillips, Pradipsinh K. Rathod, Ramesh Gujjar, Alka Marwaha, Susan A. Charman
  • ANTIMALARIAL AGENTS THAT ARE INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE
    Publication number: 20120302586
    Abstract: Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
    Type: Application
    Filed: September 28, 2010
    Publication date: November 29, 2012
    Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, MONASH UNIVERSITY, CLAYTON, GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO, S.L, UNIVERSITY OF WASHINGTON, MEDICINES FOR MALARIA VENTURE
    Inventors: Pradipsinh K. Rathod, David Floyd, Jeremy Burrows, Alka Marwaha, Ramesh Gujjar, Jose Coteron-Lopez, Margaret Phillips, Susan A. Charman, David Matthews
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY
    Publication number: 20090209557
    Abstract: Compounds according to Formula I, Formula II, Formula III, Formula V, Formula VI, or to Formula VII, and pharmaceutical compositions of compounds that conform to Formula IV or Formula VIII: where R1 through R33 are prescribed, selectively inhibit P. falciparum dihydroorotate dehydrogenase. Accordingly, a method for preventing and treating malaria attaches to such compounds, as well as to pharmaceutically acceptable salts, solvates, stereoisomers, tautomers, and prodrugs thereof.
    Type: Application
    Filed: December 19, 2008
    Publication date: August 20, 2009
    Inventors: Margaret PHILLIPS, Pradipsinh K. Rathod, Ramesh Gujjar, Alka Marwaha, Susan A. Charman