Patents by Inventor Alla BALABANOVA

Alla BALABANOVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anthracycline prodrugs and methods of making and using the same
    Patent number: 10912767
    Abstract: The present invention includes compounds of the class anthracycline that have been modified to include photo-activated prodrug anthracycline compounds that are useful in the treatment of cancer. One example composition of the invention may include photodoxazolidine which may be synthesized in two steps from 4,5-dimethoxy-2-nitrobenzyl alcohol and doxazolidine. In this embodiment commercial 4,5-dimethoxyl-2-nitrobenzyl alcohol reacts with p-nitrophenylchloroformate to give the p-nitrophenyl carbonate of the benzyl alcohol derivative. The p-nitrophenyl carbonate is then reacted with doxazolidine to give the exemplary photodoxazolidine composition.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: February 9, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Tad H. Koch, Benjamin L. Barthel, Hang Hubert Yin, Ryo Tamura, Alla Balabanova
  • ANTHRACYCLINE PRODRUGS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20180110756
    Abstract: Therapeutically effective prodrug compounds for the prevention and treatment of cancer and pharmaceutical compositions containing these compounds as well as methods of making and using these compounds.
    Type: Application
    Filed: April 27, 2016
    Publication date: April 26, 2018
    Inventors: Tad H. KOCH, Benjamin L. BARTHEL, Hang Hubert YIN, Ryo TAMURA, Alla BALABANOVA