Patents by Inventor Alla Karpova

Alla Karpova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11939355
    Abstract: The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: March 26, 2024
    Assignee: Howard Hughes Medical Institute
    Inventors: Joshua Dudman, Adam Hantman, Bum-Yeol Hwang, Alla Karpova, Loren Looger, Kimberly Ritola, David Schaffer, Dougal Gowanlock Robinson Tervo, Sarada Viswanathan
  • Publication number: 20210322405
    Abstract: The present disclosure provides for compositions and methods of treating cancer. In some embodiments, PTPN11 is targeted with and anti-PTPN11 drug, such as a Shp2 inhibitor (e.g., SHP099). In some embodiments, other upregulated, hyperphosphorylated, or hyperacetylated target proteins are inhibited or targeted.
    Type: Application
    Filed: April 15, 2021
    Publication date: October 21, 2021
    Inventors: Li Ding, Song Cao, Yige Wu, Alla Karpova, Liang-Bo Wang, Milan Chheda, Feng Chen, Ramaswamy Govindan, Albert Kim, Michael Gillette, Steven Carr, Shankha Satpathy, Tao Liu, Karin D. Rodland, Richard D. Smith
  • Publication number: 20210246185
    Abstract: This document provides methods and materials for modulating one or more properties of transporter proteins. For example, inverted transporter polypeptides including a leader sequence fused to a transporter protein, and methods of using one or more inverted transporter polypeptides to modulate (e.g., stimulate or inhibit) the excitability of one or more cells (e.g., neurons and myocytes) are provided.
    Type: Application
    Filed: June 4, 2019
    Publication date: August 12, 2021
    Inventors: Jennifer Brown, Reza Behnam, Luke Coddington, Dougal Gowanlock Robinson Tervo, Joshua Dudman, Alla Karpova
  • Publication number: 20210230231
    Abstract: The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.
    Type: Application
    Filed: March 23, 2021
    Publication date: July 29, 2021
    Inventors: Joshua Dudman, Adam Hantman, Bum-Yeol Hwang, Alla Karpova, Loren Looger, Kimberly Ritola, David Schaffer, Dougal Gowanlock Robinson Tervo, Sarada Viswanathan
  • Patent number: 10961282
    Abstract: The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: March 30, 2021
    Assignees: Howard Hughes Medical Institute, The Regents of the University of California
    Inventors: Joshua Dudman, Adam Hantman, Bum-Yeol Hwang, Alla Karpova, Loren Looger, Kimberly Ritola, David Schaffer, Dougal Gowanlock Robinson Tervo, Sarada Viswanathan
  • Publication number: 20190300579
    Abstract: The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 3, 2019
    Inventors: Joshua Dudman, Adam Hantman, Bum-Yeol Hwang, Alla Karpova, Loren Looger, Kimberly Ritola, David Schaffer, Dougal Gowanlock Robinson Tervo, Sarada Viswanathan
  • Publication number: 20050288247
    Abstract: The invention provides molecular systems for inducible and reversible inactivation of synaptic transmission. These systems can be used for studying neuronal networks and for treating conditions involving abnormally high neuronal activity or excitotoxic damage.
    Type: Application
    Filed: June 24, 2005
    Publication date: December 29, 2005
    Inventors: Karel Svoboda, Alla Karpova