Abstract: An effective composite for absorbing both standing and flowing water which comprises a fumed silica component, a water-absorbent acrylic polymer a fibrous component, and three types of scoriaceous components is described. Bags containing the composite may also be used.

Abstract: The invention employs composites of zeolite and ferric oxide hydroxide for removal of inorganic nitrogen and phosphorus wastes from animal environments.

Abstract: Compositions and methods are disclosed for remediating environmental contaminants when such contaminants primarily include hydrophobic materials such as petroleum.

Abstract: Compositions and methods for heavy metal remediation are disclosed. The compositions contain ceramic nanoparticulate cation exchangers specific for at least one heavy metal as well as at least one carrier, typically a thickener, a gel forming agent and/or a cross-binding agent. The compositions may also contain chelating agents as well as beneficial agents such as vitamins and pharmaceuticals, with or without the ceramic nanoparticulate cation exchangers.

Abstract: Nanocomposite compositions forming mixed clathrates and methods for using such compositions for entrapping guest moieties such as malodors, molds and cells are disclosed.

Abstract: An effective composite for absorbing both standing and flowing water which comprises a fumed silica component, a water-absorbent acrylic polymer a fibrous component, and three types of scoriaceous components is described. Bags containing the composite may also be used.

Abstract: The invention employs composites of zeolite and ferric oxide hydroxide for removal of inorganic nitrogen and phosphorus wastes from animal environments.

Abstract: Nanocomposite compositions forming mixed clathrates and methods for using such compositions for entrapping guest moieties such as malodors, molds and cells are disclosed.

Abstract: Compositions and methods for heavy metal remediation are disclosed. The compositions contain ceramic nanoparticulate cation exchangers specific for at least one heavy metal as well as at least one carrier, typically a thickener, a gel forming agent and/or a cross-binding agent. The compositions may also contain chelating agents as well as beneficial agents such as vitamins and pharmaceuticals, with or without the ceramic nanoparticulate cation exchangers.

Abstract: Compositions and methods are disclosed for remediating environmental contaminants when such contaminants primarily include hydrophobic materials such as petroleum.

Abstract: The inventive material is a unique family of externally used wound sealants based upon a binding agent of reactive submicron silica particles that, when hydrated, agglomerate in the form of a supramolecular cross-linked network serving as the structural framework facilitating clot formation. A thrombolytic cascade accelerant can be provided, optionally with additional clotting factors, to further accelerate the clotting process.

Abstract: Described herein are compositions and methods related to wound treatment. Compositions are multi-components admixed in amounts and ratios to meet specific objectives for optimally treating various types of wound injury.

Abstract: This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complementary specific binding pair members for the analyte and a novel arrangement of capture zones comprising immobilized specific binding substances for either the analyte or the labelled reagent to effect bound from unbound labelled reagent as a function of analyte concentration. The capture zones are disposed on a non-bibulous matrix defining a flow path from a sample receiving zone to the capture zone. The devices of this invention also include multilane flow paths and multiple capture zones to quantitate analyte.

Abstract: Methods and apparatus for measuring a carbohydrate in a fluid are presented. An amperometric glucose sensor system suitable for glucose monitoring in a biological sample other than blood includes a support member having a sample region defined thereon in fluid communication with a measurement zone including an electrode having an exposed surface area. Biological sample fluid is transported from the sample region to the measurement zone, which includes an exposed catalyst in communication with the electrode providing a minimum sensitivity of at least about 50 micromolar glucose concentration and a noise level of less than about 0.5 nA/?M/mm2. In some embodiments, at least one of a nanofiltration material and a porous absorbent material is provided between the sample region and the measurement zone.

Abstract: The present invention relates to serous fluid collection devices, and methods of using the same to collect orally samples of enriched serous fluid suitable for a target diagnostic medical procedure. Sample collection devices include at least one sample inducing region adapted to induce a flow of enriched serous fluid, and at least one sample collection member, such as a sponge, adapted to collect a suitable sample volume as determined by the target assay. The sample inducing region is adapted to induce blood equivalent levels of serous fluid flow by one or more chemical, physical, or biological induction means. In some embodiments, means are optionally provided to visually mask erythrocytes contained within the collected sample.

Abstract: This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complementary specific binding pair members for the analyte and a novel arrangement of capture zones comprising immobilized specific binding substances for either the analyte or the labelled reagent to effect bound from unbound labelled reagent as a function of analyte concentration. The capture zones are disposed on a non-bibulous matrix defining a flow path from a sample receiving zone to the capture zone. The devices of this invention also include multilane flow paths and multiple capture zones to quantitate analyte.

Abstract: This invention relates to low molecular weight analyte sequestration, storage, transport and recovery device and methods for its use with saliva samples in the detection of glucose and other low molecular weight analytes. A stimulated or non-stimulated saliva sample is contacted with a matrix (16) disposed within a container (12) that adsorbs glucose, absorbs water and excludes molecules above a certain size when hydrated. After hydration of the matrix by the saliva sample, the glucose is both adsorbed to the matrix, and migrates into the cavities within the matrix, whereas microbes such as bacteria and larger molecules such as proteins cannot. A membrane (18) keeps the matrix (16) in the bottom of the container (12). The sample is then transported to a location where the glucose will be eluted from the matrix and assayed.

Abstract: One-step enzyme immunoassays in which enzyme-antibody conjugate or label and enzyme substrate are separated until separation of bound and free enzyme conjugate or label is complete. This separation is accomplished by using variable flow paths, immobilization of substrate at the test line, placement of substrate in a sac or association with a particle label, enzyme product chemical capture, delay zone dissolution and protected enzyme substrates.

Abstract: One-step enzyme immunoassays in which enzyme-antibody conjugate or label and enzyme substrate are separated until separation of bound and free enzyme conjugate or label is complete. This separation is accomplished by using variable flow paths, immobilization of substrate at the test line, placement of substrate in a sac or association with a particle label, enzyme product chemical capture, delay zone dissolution and protected enzyme substrates.

Abstract: The efficiency and accuracy of one-step lateral flow assays can be improved by employing more efficient binding between participants in labeling and capture. Thus, in addition to analyte/anti-analyte interactions, specific binding is achieved through members of an irrelevant specific binding pair. Also included within the invention is a format wherein unlabeled competitor for analyte serves as a gatekeeper in the capture zone, competing with analyte for labeled anti-analyte, which analyte will be captured in a detecting portion of a capture zone.