Patents by Inventor Allan G. A. Coombes

Allan G. A. Coombes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of protein microspheres, films and coatings
    Patent number: 6592844
    Abstract: A process is described for preparing microspheres, films and coatings from protein or modified protein in which the protein product is stabilized by carrying out the preparation in the presence of an aqueous solution of at least one &agr;-hydroxy acid. The microspheres, films and coatings so produced have improved stability in aqueous solution.
    Type: Grant
    Filed: December 27, 1999
    Date of Patent: July 15, 2003
    Assignees: Chiron Corporation, University of Nottingham
    Inventors: Allan G. A. Coombes, Wu Lin, Derek T. O'Hagen, Stanley S. Davis
  • PREPARATION OF PROTEIN MICROSPHERES, FILMS AND COATINGS
    Publication number: 20020182146
    Abstract: A process is described for preparing microspheres, films and coatings from protein or modified protein in which the protein product is stabilized by carrying out the preparation in the presence of an aqueous solution of at least one alpha-hydroxy acid. Preferred alpha-hydroxy acids are glycolic acid, lactic acid, alpha-hydroxybutyric acid or a mixture of two or more thereof. The microspheres, films and coatings so produced have improved stability in aqueous solution.
    Type: Application
    Filed: December 27, 1999
    Publication date: December 5, 2002
    Inventors: ALLAN G. A. COOMBES, WU LIN, DEREK T. O'HAGEN, STANLEY S. DAVIS
  • Preparation of protein microspheres, films and coatings
    Patent number: 6007791
    Abstract: A process is described for preparing microspheres, films and coatings from protein or modified protein in which the protein product is stabilized by carrying out the preparation in the presence of an aqueous solution of at least one .alpha.-hydroxy acid. Preferred .alpha.-hydroxy acids are glycolic acid, lactic acid, .alpha.-hydroxybutyric acid or a mixture of two or more thereof. The microspheres, films and coatings so produced have improved stability in aqueous solution.
    Type: Grant
    Filed: July 9, 1997
    Date of Patent: December 28, 1999
    Assignee: Chiron Corporation
    Inventors: Allan G. A. Coombes, Wu Lin, Derek T. O'Hagen, Stanley S. Davis
  • Resorbable materials based on independently gelling polymers of a single enantiomeric lactide
    Patent number: 5397572
    Abstract: Resorbable materials and their preparation based on gelling a solution of a single polylactide enantiomer. The gel may be dried to produce solid materials, or may be extracted with a nonsolvent prior to drying to make microporous materials. Physical and mechanical properties of the material may be varied by varying the molecular weight of the gelling polymer, or by blending the gelling solution with other polymers or fillers. The resorbable materials can be used to make biodegradable implantation devices.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: March 14, 1995
    Assignee: Board of Regents, The University of Texas System
    Inventors: Allan G. A. Coombes, James D. Heckman, Barbara D. Boyan
  • Process of making a resorbable implantation device
    Patent number: 5290494
    Abstract: Resorbable materials and their preparation based on gelling a solution of a single polylactide enantiomer. The gel may be dried to produce solid materials, or may be extracted with a nonsolvent prior to drying to make microporous materials. Physical and mechanical properties of the material may be varied by varying the molecular weight of the gelling polymer, or by blending the gelling solution with other polymers or fillers. The resorbable materials can be used to make biodegradable implantation devices.
    Type: Grant
    Filed: July 16, 1992
    Date of Patent: March 1, 1994
    Assignee: Board of Regents, The University of Texas System
    Inventors: Allan G. A. Coombes, James D. Heckman, Barbara D. Boyan