Abstract: The present invention relates generally to a method for the treatment and prophylaxis of pain. In accordance with the present invention, it is proposed that antagonists of GM-CSF are effective in the treatment of pain. Antagonists of GM-CSF include, but are not limited to, antibodies which are specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.

Abstract: A method for the treatment of a chronic inflammatory condition in a patient which comprises administration to the patient of an agent which blocks or inhibits IL-3 signalling events in the patient.

Abstract: An Improved Circuit Design and Optics System for infrared Signal Transceivers is disclosed. The preferred system includes an IR transceiver assembly that is easily grasped by assemblers. Furthermore, the primary and secondary lenses associated with the transceiver system are easier to manufacture than are current lens designs. Also, the heretofore critical lens separation between the infrared emitting and infrared detection devices and the primary lens is rendered a flexible dimension, dependent only upon the particular appliance in which the system is installed. The present invention permits the stand for infrared emitting and infrared detection devices to be eliminated as a result of exchanging a non-imaging transceiver system with the current imaging transceiver system. The present invention further comprises assembling or otherwise combining infrared emitting and infrared detection devices into a single infrared emitting/infrared detection device stack.

Abstract: A System and Method for Providing an Improved Standby Mode for Infrared Data Transceivers is disclosed. Standby Mode for Infrared Data Transceivers. The device and system of the present invention includes a discovery signal receiver and power actuator module that consumes a fraction of the power of a conventional Ir transceiver system. The preferred device and system may be integral to a conventional Ir transceiver, or it may be a stand-alone system or device. Furthermore, the device and system are configured to activate full power to the Ir transceiver system upon recognition of an Ir discovery signal, and this power-up signal might also be user-initiated in some preferred embodiments. The preferred switch means for providing full power to the Ir transceiver system is in an open position while the Ir-enabled appliance is in a standby or sleep mode. The preferred device and system recognize a 9600 baud Ir discovery signal.

Abstract: An Improved Signal Receiver Having Wide Band Amplification Capability is disclosed. Also disclosed is a receiver that is able to receive and reliably amplify infrared and/or other wireless signals having frequency bandwidths in excess of 40 MHz. The receiver of the present invention reduces the signal-to-noise ratio of the received signal to ?th of the prior systems. The preferred receiver eliminates both the shunting resistor and the feedback resistor on the input end by amplifing the signal in current form. Furthermore, the receiver includes transconductance amplification means for amplifying the current signal without the need for Cascode stages. Finally, the receiver includes staged amplification to amplify the current signal in stages prior to converting the signal into a voltage output.

Abstract: An Improved Circuit Design and Optics System for Infrared Signal Transceivers is disclosed. The preferred system includes an IR transceiver assembly that is easily grasped by assemblers. Furthermore, the primary and secondary lenses associated with the transceiver system are easier to manufacture than current lens designs. Also, the heretofore critical lens separation between the infrared emitting and infrared detection devices and the primary lens is rendered a flexible dimension, dependent only upon the particular appliance in which the system is installed. The present invention permits the stand for infrared emitting and infrared detection devices to be eliminated as a result of exchanging a non-imaging transceiver system with the current imaging transceiver system. The present invention further comprises assembling or otherwise combining infrared emitting and infrared detection devices into a single infrared emitting/infrared detection device stack.

Abstract: An Improved Infrared Signal Communication System and Method Including Transmission Means Having Automatic Gain Control is disclosed. Also disclosed is system and method that adjusts signal transmission power in response to incident signal power amplitude. The preferred system includes a control signal loop within the signal receiving system, and the system further includes a signal transmitting system that is responsive to the control signal loop. The preferred system includes manual, semi-automatic and automatic modes of operation. Still further, the preferred method includes at least two Ir-enabled appliances “stepping” each other “down” in transmit power in response to directives issued by the other Ir-enabled appliance.

Abstract: An Improved Signal Receiver Having Wide Band Amplification Capability is disclosed. Also disclosed is a receiver that is able to receive and reliably amplify infrared and/or other wireless signals having frequency bandwidths in excess of 40 MHz. The receiver of the present invention reduces the signal-to-noise ratio of the received signal to ?th of the prior systems. The preferred receiver eliminates both the shunting resistor and the feedback resistor on the input end by amplifying the signal in current form. Furthermore, the receiver includes transconductance amplification means for amplifying the current signal without the need for Cascode stages. Finally, the receiver includes staged amplification to amplify the current signal in stages prior to converting the signal into a voltage output.

Abstract: A Method and System for Dynamically Managing Wireless Communications System Protocols is disclosed. Also disclosed is a method and system that automatically detects and enables the most advanced Stack and Application Sets available on a pair of devices in wireless communications with one another. The preferred device includes detector means in wireless communication with the other device or devices for detecting the configuration of the application set of the other device(s). The preferred device further includes selector means for enabling the optimum communication protocol stack responsive to the application set configuration of the other device. Furthermore, the preferred device enables the optimum internal application set responsive to the application set of the other device. Still further, the device commences (and re-establishes broken) communications using a default communication protocol stack and application set.

Abstract: An Improved Infrared Signal Communication System and Method Including Transmission Means Having Automatic Gain Control is disclosed. Also disclosed is system and method that adjusts signal transmission power in response to incident signal power amplitude. The preferred system includes a control signal loop within the signal receiving system, and the system further includes a signal transmitting system that is responsive to the control signal loop. The preferred system includes manual, semi-automatic and automatic modes of operation. Still further, the preferred method includes at least two Ir-enabled appliances “stepping” each other “down” in transmit power in response to directives issued by the other Ir-enabled appliance.

Abstract: An Improved Infrared Signal Communication System and Method Including Transmission Means Having Automatic Gain Control is disclosed. Also disclosed is system and method that adjusts signal transmission power in response to incident signal power amplitude. The preferred system includes a control signal loop within the signal receiving system, and the system further includes a signal transmitting system that is responsive to the control signal loop. The preferred system includes manual, semi-automatic and automatic modes of operation. Still further, the preferred method includes at least two Ir-enabled appliances “stepping” each other “down” in transmit power in response to directives issued by the other Ir-enabled appliance.

Abstract: A Method and System for Enabling Wireless Data Communications with Electronic Devices having Disparate Operating Systems is disclosed. Also disclosed is a system that compares the Infrared or RF communications configuration of an electronic appliance to a target profile, and then uploads the target configuration profile to the appliance, if necessary. The preferred device and system perform a functional testing on the wireless communications system of the electronic appliance, including the transceiver hardware and all device drivers and software stacks. Furthermore, the device of the present invention is able to adopt the target configuration from an electronic appliance by downloading it from one or more appliances. Still further, the device of the present invention is able to communicate with two or more electronic appliances simultaneously. The device and system of the present invention are operable independent of the BIOS of the electronic appliance(s) to be configured.

Abstract: A Method and System for Preventing Bum-out of Infrared Transmitter Diodes is disclosed. The preferred method and system detects when the Ir transmitter(s) are approaching or have achieved an overtemperature condition. Once an overtemperature condition is detected, the preferred system will interrupt electrical transmit power to the transmitter until such time as the overtemperature condition is dissipated. Furthermore, the system and method will send a standby signal to the Central Processing Unit or communications controller when an overtemperature condition is detected. Finally, it is yet another feature that the system emit status signals perceptible to the human senses when normal and abnormal temperature conditions are detected in the transmitter.

Abstract: An Improved Optics System for Infrared Signal Transceivers is disclosed. Transceivers. The preferred system includes an IR transceiver assembly that is easily grasped by assemblers. Furthermore, the primary and secondary lenses associated with the transceiver system are easier to manufacture than current lens designs. Also, the heretofore critical lens separation between the emitter/detector devices and the primary lens is rendered a flexible dimension, dependent only upon the particular appliance in which the system is installed. The present invention permits the stand for emitter/detector devices to be eliminated as a result of exchanging a non-imaging transceiver system with the current imaging transceiver system. Finally, the present invention comprises assembling or otherwise combining emitter/detector devices into a single emitter/detector device stack.

Abstract: Therapeutic compositions and methods for the treatment of inflammation are disclosed. The compositions comprise at least one anti-inflammatory drug in combination with the lymphokine interleukin-4 (IL-4), which components interact synergistically in the treatmement of inflammation. Methods for the treatment of inflammation comprise administering to a subject in need of such treatment an effective amount of at least one anti-inflammatory drug and IL-4.

Abstract: A sound system, for a band or the like, incorporates an anechoic enclosure which allows a performer to use the same desired speaker color under all performing conditions and which insulates the audience and other pick-up microphones from each sound-source's speaker and insulates the pickup microphone for each sound source from the ambient room sounds. According to the system, a sound source, such as a musical instrument, outputs a first sound signal which is amplified and fed to a speaker in an anechoic enclosure. In response to the speaker output, a microphone in the anechoic chamber outputs a second sound signal which is amplified and distributed to room speakers. In its exemplary embodiment, the anechoic enclosure comprises four laminated layers: an inner layer of rigid closed-cell foam surrounding a chamber; a layer of denser flexible, closed-cell foam; a second layer of rigid closed-cell foam; and an outer hard, rigid layer. The enclosure may be opened so that the speaker therein may be heard.

Abstract: An operational amplifier is provided with two current outputs instead of the usual one voltage output. The amplifier has two current inputs, ideally zero input impedance and ideally infinite current gain and output impedance.

Abstract: A frequency detection device adapted to detect in which of a plurality of frequency bands an input signal occurs comprises band pass filter means for selecting from the input signal the output signals in each of the bands and detecting means responsive to said output signals to stop the scanning action of the scanning means wherein the band pass filter means comprises a band pass filter and means for scanning the filter through different bands in turn, and an indicator actuated by the stopping of the scanning action to indicate the frequency band in which the input signal has occurred.