Patents by Inventor Allan I. Levey

Allan I. Levey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA splicing alterations and U1 small nuclear ribonucleoproteins in neurodegenerative diseases
    Patent number: 9758809
    Abstract: This disclosure relates to methods of diagnosing neurodegenerative disease by analyzing proteins or protein expression profiles in a subject, or RNA or RNA expression profiles in a subject. In certain embodiments, the disclosure contemplates the diagnosis of preclinical or symptomatic stages of Alzheimer's disease, mild cognitive impairment, or chronic traumatic encephalopathy by identification of components of U1 small nuclear ribonucleoproteins or fragments thereof which are capable of forming cytoplasmic tangle-like structures.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: September 12, 2017
    Assignee: Emory University
    Inventors: Allan I Levey, Junmin Peng, James Lah, Bing Bai, Chadwick McKinley Hales, Ping-Chung Chen, Nicholas Thomas Seyfried
  • RNA SPLICING ALTERATIONS AND U1 SMALL NUCLEAR RIBONUCLEOPROTEINS IN NEURODEGENERATIVE DISEASES
    Publication number: 20140255927
    Abstract: This disclosure relates to methods of diagnosing neurodegenerative disease by analyzing proteins or protein expression profiles in a subject, or RNA or RNA expression profiles in a subject. In certain embodiments, the disclosure contemplates the diagnosis of preclinical or symptomatic stages of Alzheimer's disease, mild cognitive impairment, or chronic traumatic encephalopathy by identification of components of U1 small nuclear ribonucleoproteins or fragments thereof which are capable of forming cytoplasmic tangle-like structures.
    Type: Application
    Filed: March 6, 2014
    Publication date: September 11, 2014
    Applicant: EMORY UNIVERSITY
    Inventor: Allan I Levey
  • MICRO RNA MARKERS AND METHODS RELATED THERETO
    Publication number: 20120108650
    Abstract: The present invention provides methods of diagnosis of Alzheimer's disease including assessing the levels of certain microRNAs in a subject and comparing these to levels in subjects not exhibiting the disease. The identified measurements provide input for improved diagnoses of Alzheimer's disease as compared to certain other forms of dementias, which allows more effective treatment regimens.
    Type: Application
    Filed: October 28, 2011
    Publication date: May 3, 2012
    Applicant: EMORY UNIVERSITY
    Inventors: Peng Jin, Allan I. Levey, Keith Szulwach
  • Detection of neurodegenerative diseases, in vitro screening assays
    Publication number: 20020086281
    Abstract: Applicants have discovered that a variety of neurodegenerative diseases can be diagnosed, or screened for, by the analysis of a patient's mitochondrial metabolism, and thereby provide a screening assay for therapeutic drugs for the treatment of such neurodegenerative diseases.
    Type: Application
    Filed: December 14, 2001
    Publication date: July 4, 2002
    Inventors: Timothy J. Greenamyre, James J. Lah, Julie Bennett-Desmelik, Allan I. Levey