Patents by Inventor Allan J. Tobin

Allan J. Tobin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloned glutamic acid decarboxylase
    Patent number: 8926966
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 6, 2015
    Assignee: Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Nucleic acid encoding GAD65
    Patent number: 7329511
    Abstract: The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD65. In another embodiment, the invention provides for the detection of autoantibodies to GAD65 using the GAD65 polypeptides coded for by the cDNA molecules of the invention.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: February 12, 2008
    Assignee: The Regents of The University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Cloned glutamic acid decarboxylase
    Patent number: 6682906
    Abstract: cDNA molecules coding for GAD65 polypeptide are disclosed. The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD65. In another embodiment, the invention provides for the detection of autoantibodies to GAD65 using the GAD65 polypeptides coded for by the cDNA molecules of the invention.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: January 27, 2004
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Methods and kits useful for determining the status of and detecting pancreatic B-cell associated autoimmune diseases
    Patent number: 6455267
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 24, 2002
    Assignees: Diamyd Medical AB, RSR Limited, Perkin Elmer Life Sciences
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Cloned glutamic acid decarboxylase
    Patent number: 6277586
    Abstract: The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD65. In another embodiment, the invention provides for the detection of autoantibodies to GAD65 using the GAD65 polypeptides coded for by the cDNA molecules of the invention.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: August 21, 2001
    Assignee: Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Hybridomas and monoclonal antibodies that specifically bind to glutamic acid decarboxylase peptides
    Patent number: 6011139
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed. Monoclonal antibodies specific for GAD peptides and hybridoma cells producing such are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 4, 2000
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders
    Patent number: 5998366
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: December 7, 1999
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Methods and kits useful for detecting autoantibody to glutamic acid decarboxylase
    Patent number: 5846740
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: September 22, 1995
    Date of Patent: December 8, 1998
    Assignee: The Regents of The University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Cloned glutamic acid decarboxylase nucleic acids
    Patent number: 5705626
    Abstract: The invention is directed to isolated polypeptides useful in ameliorating autoimmune disease.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 6, 1998
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
  • Peptides derived from glutamic acid decarboxylase
    Patent number: 5674978
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: October 7, 1997
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman, Michael J. Clare-Salzler
  • Cloned glutamic acid decarboxylase peptides
    Patent number: 5475086
    Abstract: Isolated polypeptides useful in ameliorating autoimmune disease.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: December 12, 1995
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman, Michael J. Clare-Salzler