Abstract: A detent hinge firmly secures the door of a containment system in an upward position, downward position, and optionally at pre-determined positions therebetween. The hinge generally includes two hinge assemblies each including a leaf and one or two knuckles, with the knuckles of both assemblies aligned end-to-end. The two hinge assemblies are independently rotatable relative to each other but share a rotational axis. The hinge is locked and the door is substantially immovable due to a spring-activated cam that impedes rotation of the hinge assemblies relative to each other. The hinge is unlocked by depressing a plunger which repositions the cam such that the hinge assemblies can freely rotate relative to each other, and the door can be raised or lowered.

Abstract: A graphene-based lubricant is provided that includes a graphene-based additive. The graphene-based additive, along with and other optional additives is dispersed in a base liquid. A method of lubrication is also provided that includes the application of the composition to two mating surfaces to form a protective coating between the two mating surfaces.

Abstract: Embodiments permit secure information exchange using lightweight data and near-field communication (NFC). A user can transmit lightweight data, such as one or more indicators (e.g., user indicator, scope indicator(s), documents indicator(s), etc.), to a receiving computing system via the user's wireless device and an NFC protocol. Because NFC transmissions are performed by co-located devices, this lightweight data transmission can trigger and/or continue a sophisticated workflow. For example, the receiving computing system can be associated with a product or service provider, and the lightweight data transmission can progress a workflow related to a particular product and/or service. The workflow progression can include accessing secure user information via the indicator(s) received over the NFC transmission.

Abstract: A rollator to aid mobility is described. The rollator comprises an A-frame with two pairs of uprights, each pair of uprights connected by at least one respective hinge to allow each pair of uprights to be folded or pivot front-to-back and a seat disposed between the two pairs of uprights, the seat foldable side-to-side. To fold compactly the rollator comprises an X-shaped cross-linkage comprising four linkage members. A method of manufacturing the rollator is also disclosed. The four linkage members may extend from a respective upright to a central hub underneath the seat. The cross-linkage may fold or pivot at the central hub in both front-to back and side-to-side dimensions when the rollator is folded away.

Abstract: The present invention is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to multiple antigens to form multi functionalized nOMV-antigen conjugated derivatives, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates are also provided.

Abstract: A graphene-based lubricant is provided that includes a graphene-based additive. The graphene-based additive, along with and other optional additives is dispersed in a base liquid. A method of lubrication is also provided that includes the application of the composition to two mating surfaces to form a protective coating between the two mating surfaces.

Abstract: The provided technology is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to antigens to form nOMV-antigen conjugates, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates is also provided.

Abstract: A negative pressure containment system is configured to run in lateral air flow mode or enhanced controlled environment mode, depending on the operator's needs. A diverter assembly facilitates switching between modes by directing air into alternative air chases. In the enhanced controlled environment mode there are two concurrent air paths that eventually converge, with one path being a bypass flow that creates negative pressure in the main chamber and another path being compressed air that feeds the main chamber. In this mode it is possible to precisely control the chamber environment.

Abstract: The present invention is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to multiple antigens to form multi functionalized nOMV-antigen conjugated derivatives, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates are also provided.

Abstract: This invention relates to immunogenic compositions, particularly vaccine compositions, for use in providing protection against illness caused by bacterial infection with Shigella strains.

Abstract: Provided is an earth working tool assembly comprising: a tool shank having a leading end portion; an earth working tip having a trailing end portion that is detachably engageable with the leading end portion of the tool shank; and a fastening assembly for detachably fastening the earth working tip to the tool shank. The fastening assembly comprises: a trailing connector that is connectable to the tool shank; a leading connector that is connectable to the earth working tip; a spring mounting mechanism interposed between the trailing and leading connectors. The spring mounting mechanism is configured so that the trailing and leading connectors can be driven away from each other against a bias of the spring mounting mechanism, into and out of an operative condition in which the spring mounting mechanism acts to retain the earth working tip and the tool shank in engagement with each other.

Abstract: A formwork system includes a height-adjustable support for supporting a beam in substantially horizontal or slightly inclined position that includes a support with a central upstanding member and a support arm. The support arm has a rounded socket, and the beam has a cylindrical mounting pin proximate its end. The socket and mounting pin are shaped and sized so that the mounting pin is retained within the socket and they together form a hinge joint. As the mounting pin is retained by the socket of the support arm, it does not shift laterally relative to the support arm as the support arm is vertically adjusted. The variance in the gap between laterally secured forming panels as a response to vertical shift of the support is dependent on the incline angle of the beam and the dimensions of the beam and the support arm. This is predictable within a defined tolerance.

Abstract: A device for configuring a plough between a use configuration and a transport configuration is provided, the device comprising an elongated support and an actuator connected with the elongated support, wherein the elongated support is for sliding connection with the plough, and the actuator is for actuating connection with the plough, and wherein when the elongated support and the actuator are connected with the plough, actuation of the actuator can slide the plough relative to the elongated support to configure the plough between the use configuration and the transport configuration. Related systems and methods are also provided.

Abstract: A method of validating a test for estimating the organic carbon content of soil or changes in organic carbon content of soil over time in which a first sample of soil is taken from a selected location and heated using Loss On Ignition (LOI) to remove organic carbon, the method comprising the steps of taking a further sample of soil from an adjacent location, the sample having minimal organic material content. A predetermined quantity of an organic material is added to the further sample to provide a second sample which is heated using Loss On Ignition (LOI) with the change of weight of the second sample determining whether the test of the first sample yielded a valid estimate of the organic carbon content of the first sample. Apparatus (10) for use in performing the method is also disclosed.

Abstract: A filter media is formed into a filter bag for fluid filter elements. A long tube of filter media is formed into a helix or a pleated structure with a corrugated cross-section to increase the surface area of filter media area that can fit into a given volume. A retaining structure can be used to maintain the shape of the filter media.

Abstract: A Shigella flexneri O-antigen of a first serotype or subserotype are provided for use in raising an immune response against one or more Shigella flexneri O-antigen of a different serotype or subserotype, together with associated binding moieties, pharmaceutical compositions, kits, uses or methods.

Abstract: The provided technology is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to antigens to form nOMV-linker-antigen conjugates, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates is also provided.

Abstract: Graphene-modified polymeric foam materials are provided that are amenable to conventional foams to yield articles with superior properties relative to like articles absent the graphene cell modifier. Graphene-based cell modifiers are incorporated in the polymer before or during the foaming process to not only improve the mechanical, thermal, electrical, fire retardant, or barrier properties of the polymer matrix itself, but also help modify the size, density, and morphology of cells in the foam, thereby tailoring the properties of the final foam articles. The graphene-modified polymeric foam materials may be utilized for the manufacturing of articles for mechanical, thermal, noise reduction, or sound absorption applications. The graphene-modified foams and articles made thereof have the advantages higher mechanical strength, better thermal stability, and better sound absorption properties as compared to the conventional polymeric foams such as materials made by copolymer polyol.