Patents by Inventor Allan Joseph McLean

Allan Joseph McLean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
    Patent number: 6858589
    Abstract: The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatment of bacterial infection are also provided.
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: February 22, 2005
    Assignee: Pharmacy and Therapeutic Advisory Consultancy Pty LTD
    Inventor: Allan Joseph McLean
  • Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
    Publication number: 20030096766
    Abstract: The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatment of bacterial infection are also provided.
    Type: Application
    Filed: July 23, 2002
    Publication date: May 22, 2003
    Inventor: Allan Joseph McLean
  • Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
    Patent number: 6475992
    Abstract: The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatment of bacterial infection are also provided.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: November 5, 2002
    Assignee: Pharmacy and Therapeutic Advisory Consultancy Pty LTD
    Inventor: Allan Joseph McLean
  • METHODS OF AND COMPOSITIONS FOR POTENTIATING THE ACTION OF AGENTS ACTIVE ON CELL WALL SITES OF THE SUSCEPTIBLE BACTERIA
    Publication number: 20020049171
    Abstract: The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatement of bacterial infection are also provided.
    Type: Application
    Filed: August 26, 1998
    Publication date: April 25, 2002
    Inventor: ALLAN JOSEPH MCLEAN
  • Method of treating liver disease and like indications with vasodilating agents
    Patent number: 6174917
    Abstract: Liver diseases, such as cirrhosis of the liver, toxic and medicamentary liver damage, a liver-parenchymic disorder or hepatitis, are treated by administering to a human or animal subject in need thereof a therapeutically active or prophylactically effective low dose amount of a vasodilating agent which selectively increases the supply of oxygenated blood to the liver by increasing hepatic arterial inflow; Suitable vasodilating agents include calcium blockers, such as a benzothiazepine derivative, nifedipine, felodipine or verapamil.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: January 16, 2001
    Assignee: Pharmacy and Therapeutic Advisory Consultancy Ltd.
    Inventor: Allan Joseph McLean
  • Method of treating liver disease and like indications with vasodilating agents
    Patent number: 5854233
    Abstract: Liver diseases, such as cirrhosis of the liver, toxic and medicamentary liver damage, a liver-parenchymic disorder or hepatitis, are treated by administering to a human or animal subject in need thereof a therapeutically active or prophylactically effective low dose amount of a vasodilating agent which selectively increases the supply of oxygenated blood to the liver by increasing hepatic arterial inflow. Suitable vasodilating agents include calcium blockers, such as a benzothiazepine derivative, nifedipine, felodipine or verapamil.
    Type: Grant
    Filed: June 20, 1996
    Date of Patent: December 29, 1998
    Assignee: Pharmacy and Therapeutic Advisory Consultancy Ltd.
    Inventor: Allan Joseph McLean