Abstract: The present invention is directed to methods for treating diseases in which IL-13 activity is detrimental, including eosinophilic esophagitis (EoE) and asthma, by administering to a subject in need of such treatment, a composition containing an interleukin-13 (IL-13) antibody, or an antigen binding fragment, thereof.

Abstract: An earthquake restraint grid framework structure includes a grid framework structure for supporting a load handling device operative to move one or more containers in a stack. The grid framework structure includes intersecting grid members arranged to form a grid having plural f substantially rectangular frames in a horizontal plane, each of the substantially rectangular frames constituting a grid cell. The grid is supported by plural upright columns at each of the intersections of grid members to form a plurality of vertical storage locations for containers to be stacked between the upright columns and be guided in a vertical direction through the substantially rectangular frames. An exoskeleton includes plural vertical frame columns braced by at least one bracing member, the grid being further supported by the exoskeleton to form a seismic restraint system (SFRS).

Abstract: The present invention is directed to methods for treating diseases in which IL-13 activity is detrimental, including eosinophilic esophagitis (EoE) and asthma, by administering to a subject in need of such treatment, a composition containing an interleukin-13 (IL-13) antibody, or an antigen binding fragment, thereof.

Abstract: The present invention is directed to methods for treating diseases in which IL-13 activity is detrimental, including eosinophilic esophagitis (EoE) and asthma, by administering to a subject in need of such treatment, a composition containing an inter leukin-13 (IL-13) antibody, or an antigen binding fragment, thereof.

Abstract: The present invention is directed to methods for treating diseases in which IL-13 activity is detrimental, including eosinophilic esophagitis (EoE) and asthma, by administering to a subject in need of such treatment, a composition containing an inter leukin-13 (IL-13) antibody, or an antigen binding fragment, thereof.

Abstract: An implantable system includes terminals, a pulse generator, a sensing circuit, separate signal processing channels, and first, second and third multiplexers. The terminals are connected to electrodes via conductors of leads. Different subsets of the electrodes are used to define different electrical pulse delivery vectors, and different subsets of the electrodes are used to define different sensing vectors. The pulse generator produces electrical pulses, and the sensing circuit senses a signal indicative of an impedance associated with a selected sensing vector. The first multiplexer selectively connects outputs of the pulse generator to a selected one of the different electrical pulse delivery vectors at a time. The second multiplexer selectively connect inputs of the sensing circuit to a selected one of the different sensing vectors at a time. The third multiplexer selectively connects an output of the sensing circuit to one of the plurality of separate signal processing channels at a time.

Abstract: An implantable system includes terminals, a pulse generator, a sensing circuit, separate signal processing channels, and first, second and third multiplexers. The terminals are connected to electrodes via conductors of leads. Different subsets of the electrodes are used to define different electrical pulse delivery vectors, and different subsets of the electrodes are used to define different sensing vectors. The pulse generator produces electrical pulses, and the sensing circuit senses a signal indicative of an impedance associated with a selected sensing vector. The first multiplexer selectively connects outputs of the pulse generator to a selected one of the different electrical pulse delivery vectors at a time. The second multiplexer selectively connect inputs of the sensing circuit to a selected one of the different sensing vectors at a time. The third multiplexer selectively connects an output of the sensing circuit to one of the plurality of separate signal processing channels at a time.

Abstract: An implantable system includes terminals, a pulse generator, a sensing circuit, separate signal processing channels, and first, second and third multiplexers. The terminals are connected to electrodes via conductors of leads. Different subsets of the electrodes are used to define different electrical pulse delivery vectors, and different subsets of the electrodes are used to define different sensing vectors. The pulse generator produces electrical pulses, and the sensing circuit senses a signal indicative of an impedance associated with a selected sensing vector. The first multiplexer selectively connects outputs of the pulse generator to a selected one of the different electrical pulse delivery vectors at a time. The second multiplexer selectively connect inputs of the sensing circuit to a selected one of the different sensing vectors at a time. The third multiplexer selectively connects an output of the sensing circuit to one of the plurality of separate signal processing channels at a time.

Abstract: The present invention generally relates to implantable medical devices, such as pacemakers, and, in particular, to a method and an implantable medical device capable of detecting the presence of noise caused by external noise sources. Voltages and/or impedances are measured over one or several electrode configurations. Based on the measured voltages and/or impedances, noise parameters are calculated, which are compared with reference values to detect the presence of noise. In another aspect of the invention, at least two different electrode configurations with different noise pick-up areas are used in the measurement. Relations between the noise parameters of the at least two vectors are calculated and compared with reference relations to detect the presence of noise.

Abstract: An implantable system includes terminals, a pulse generator, a sensing circuit, separate signal processing channels, and first, second and third multiplexers. The terminals are connected to electrodes via conductors of leads. Different subsets of the electrodes are used to define different electrical pulse delivery vectors, and different subsets of the electrodes are used to define different sensing vectors. The pulse generator produces electrical pulses, and the sensing circuit senses a signal indicative of an impedance associated with a selected sensing vector. The first multiplexer selectively connects outputs of the pulse generator to a selected one of the different electrical pulse delivery vectors at a time. The second multiplexer selectively connect inputs of the sensing circuit to a selected one of the different sensing vectors at a time. The third multiplexer selectively connects an output of the sensing circuit to one of the plurality of separate signal processing channels at a time.

Abstract: The present invention is a wood splitting apparatus that includes a trailer hitch that releasably couples the wood splitting apparatus to a vehicle, an oil reservoir that contains hydraulic oil to operate the wood splitting apparatus and a plurality of hydraulic control valves with a plurality of hydraulic hoses, where the hydraulic hoses extend from the hydraulic control valves to the oil reservoir and where the hydraulic control valves control a splitting wedge movably disposed on the second end of the wood splitting apparatus. The apparatus also includes a base table that receives a wood chunk that removably rests on the base table and a base trailer that transports the wood splitting apparatus with the vehicle.

Abstract: A pulse generating implantable medical device comprises a power source , a control unit, a plurality of switching units, a timing unit, a pulse generating unit adapted to generate one or more stimulation pulses to be applied to human or animal tissue via one or more stimulation electrodes, and a coupling capacitor in series with each stimulation electrode. A stimulation pulse is adapted to be applied during a stimulation pulse timing cycle that includes a stimulation phase and a recharge phase, and that the timing of a stimulation pulse timing cycle is controlled by the control unit via the timing unit and the switching units. The implantable medical device further comprises an energy storage unit and that, during the recharge phase, one or more of the switching units is adapted to establish electrical connection between the one or many stimulation electrodes and the energy storage unit in order to collect and store energy from applied stimulation pulses.

Abstract: Extruded, directly expanded, high fiber reduced calorie food products, such as a ready-to-eat (RTE) cereal or sweet or savory snack, are produced at high production rates without substantial loss of extrusion functionality and extrudability by replacing a substantial portion of at least one flour with a gelatinized, enzyme-resistant starch type III ingredient or bulking agent as a reduced-calorie, high fiber flour replacer. The resistant starch type III ingredient or bulking agent contains an enzyme-resistant starch type III having a melting point with an endothermic peak temperature of at least about 140° C., and may have a water-holding capacity of less than 3 grams water per gram of the starch-based bulking agent. The total dietary fiber retention of the gelatinized, starch-based bulking agent may be at least about 90% by weight after extrusion using a die temperature of least about 100° C., and a die pressure of at least about 150 psig.

Abstract: The present invention generally relates to implantable medical devices, such as pacemakers, and, in particular, to a method and an implantable medical device capable of detecting the presence of noise caused by external noise sources. Voltages and/or impedances are measured over one or several electrode configurations. Based on the measured voltages and/or impedances, noise parameters are calculated, which are compared with reference values to detect the presence of noise. In another aspect of the invention, at least two different electrode configurations with different noise pick-up areas are used in the measurement. Relations between the noise parameters of the at least two vectors are calculated and compared with reference relations to detect the presence of noise.

Abstract: An apparatus, program product and method utilize metadata collected for a lock in a computer program to determine an optimal lock acquisition strategy for the lock. The metadata is typically collected via profiling of the computer program to determine a wait characteristic for the lock in the particular runtime environment in which the computer program executes, and the metadata is used to select from among different lock access implementations to be used to attempt to acquire the lock, often enabling an optimum lock access implementation to be selected for a lock.

Abstract: In an embodiment, an instant message is received that includes data, a privacy indication, and an override indication. In an embodiment, if the privacy indication specifies that the data is non-private, then the data is presented. But, if the privacy indication specifies that the data is private, then a privacy notice is presented and the data is hidden until an acknowledgment of the privacy notice is received. The privacy notice may include a prompt for the acknowledgment. In an embodiment, if the privacy indication specifies that the data is private and the override indication allows the privacy indication to be overridden, the data is presented. In another embodiment, if the privacy indication specifies that the data is private, the override indication allows the privacy indication to be overridden, and a time period since a user interface device received input is less than a threshold amount of time, then the data is presented.

Abstract: In a method and device for measuring an electrical bio-impedance of a patient at least one impedance measurement signal is generated by a current pulse generator, the signal having at least one asymmetric multiphasic impedance measurement waveform that is asymmetric in term of pulse amplitude and/or pulse width relative to the operating voltage of the current pulse generator. The waveform has a DC component that is substantially equal to zero, and is adapted to the available voltage headroom of an implantable device that contains the current pulse generator. The impedance measurement signal with the aforementioned waveform is applied to a patient and a resulting impedance signal is produced thereby, from which at least one impedance value is determined.

Abstract: An apparatus, program product and method improve management of available computing resources by adjusting use of the resource over a first interval according to actual use of the resource during a second interval. This feature enables a computing resource to exceed its normal limits during the first interval of operation. Use during the second interval may be limited to balance out the burst, or excessive resource usage of the first interval.

Abstract: An extruded, directly expanded, high fiber reduced calorie food product, such as a ready-to-eat (RTE) cereal or sweet or savory snack, is produced at high production rates without substantial loss of extrusion functionality and extrudability by replacing a substantial portion of at least one flour with a gelatinized, enzyme-resistant starch type III ingredient or bulking agent as a reduced-calorie, high fiber flour replacer. The resistant starch type III ingredient or bulking agent contains an enzyme-resistant starch type III having a melting point with an endothermic peak temperature of at least about 140° C., and may have a water-holding capacity of less than 3 grams water per gram of the starch-based bulking agent. The total dietary fiber retention of the gelatinized, starch-based bulking agent may be at least about 90% by weight after the extrusion using a die temperature of least about 100° C., and a die pressure of at least about 150 psig.

Abstract: An extruded, directly expanded, high fiber reduced calorie food product, such as a ready-to-eat (RTE) cereal or sweet or savory snack, is produced at high production rates without substantial loss of extrusion functionality and extrudability by replacing a substantial portion of at least one flour with a gelatinized, enzyme-resistant starch type III ingredient or bulking agent as a reduced-calorie, high fiber flour replacer. The resistant starch type III ingredient or bulking agent contains an enzyme-resistant starch type III having a melting point with an endothermic peak temperature of at least about 140° C., and may have a water-holding capacity of less than 3 grams water per gram of the starch-based bulking agent. The total dietary fiber retention of the gelatinized, starch-based bulking agent may be at least about 90% by weight after the extrusion using a die temperature of least about 100° C., and a die pressure of at least about 150 psig.