Patents by Inventor Allan S. Pollock

Allan S. Pollock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective induction of cell death by delivery of amino-terminal interleukin-1-? pro-piece polypeptide
    Patent number: 7176179
    Abstract: The present invention is directed to compositions and methods for selective induction of apoptosis in cancer cells, particularly malignant cancer cells, by delivery of a IL-1? propiece polypeptide (e.g., a native IL-1? propiece polypeptide, including IL-1? propiece polypeptide variant) to a cancer cell.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: February 13, 2007
    Assignee: The Regents of the University of California
    Inventors: Allan S. Pollock, David H. Lovett, Johanna Turck
  • Method for restoring glucose responsiveness to insulin secretion
    Patent number: 6319495
    Abstract: This invention comprises engineered cells that express a nucleic acid that encodes a calbindin molecule, and exhibit the ability to secrete insulin in a glucose-sensitive fashion. This invention also comprises an artificial tissue that, when implanted into recipients that do not secrete insulin in a glucose-sensitive fashion, imparts to the recipients the ability to secrete insulin in a glucose-sensitive fashion. The artificial tissue comprises engineered cells that express a nucleic acid that encodes a calbindin molecule and secrete insulin in a glucose-sensitive fashion, enclosed by a semipermeable porous matrix.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: November 20, 2001
    Assignee: The Regents of the University of California
    Inventors: Allan S. Pollock, Sylvia Christakos, Daphne Reddy
  • Selective induction of cell death by delivery of amino-terminal interleukin-1-&agr; pro-piece polypeptide
    Patent number: 6191269
    Abstract: The present invention is directed to compositions and methods for selective induction of apoptosis in cancer cells, particularly malignant cancer cells, by delivery of a IL-1&agr; propiece polypeptide (e.g., a native IL-1&agr; propiece polypeptide, including IL-1&agr; propiece polypeptide variant) to a cancer cell.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: February 20, 2001
    Assignee: The Regents of the University of California
    Inventors: Allan S. Pollock, David H. Lovett, Johanna Turck