Patents by Inventor Allan W. Rey

Allan W. Rey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
    Patent number: 7935817
    Abstract: Provided are a cocrystal of Adefovir dipivoxil and nicotinamide as well as a cocrystal of Adefovir dipivoxil and salicylamide cocrystal and processes for the preparation thereof.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: May 3, 2011
    Assignee: Apotex Pharmachem Inc.
    Inventors: Peter Garth Blazecka, Daqing Che, Cameron L. McPhail, Allan W. Rey
  • ATORVASTATIN CALCIUM PROPYLENE GLYCOL SOLVATES
    Publication number: 20110065931
    Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.
    Type: Application
    Filed: November 15, 2010
    Publication date: March 17, 2011
    Applicant: APOTEX PHARMACHEM INC.
    Inventors: K.S. Keshava Murthy, Yajun Zhao, Allan W. Rey, Daqing Che, David A. Stradiotto, Uma Kotipalli
  • Atorvastatin calcium propylene glycol solvates
    Patent number: 7834195
    Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: November 16, 2010
    Assignee: Apotex Pharmachem Inc.
    Inventors: K. S. Keshava Murthy, Yajun Zhao, Allan W. Rey, Daqing Che, David A. Stradiotto, Uma Kotipalli
  • Preparation of acid addition salts of ziprasidone and intermediates thereof by solid phase-gas phase reactions
    Patent number: 7745624
    Abstract: A process for the preparation of an acid addition salt of ziprasidone base and intermediates thereof comprising exposing the ziprasidone base in solid form to a gaseous acid in a substantially dry environment.
    Type: Grant
    Filed: June 29, 2005
    Date of Patent: June 29, 2010
    Assignee: Apotex Pharma Chem Inc.
    Inventors: Allan W. Rey, Lotfi Derdour, K.S. Keshava Murthy, Probal Kanti Datta, Martin Ehlert, Stephen E. Home
  • Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
    Patent number: 7696183
    Abstract: A novel form of Ibandronate sodium which is particularly suitable for pharmaceutical applications, and a process for preparing said novel form.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: April 13, 2010
    Assignee: Apotex Pharmachem Inc.
    Inventors: David A. Stradiotto, Allan W. Rey, Probal Kanti Datta, Krista Lyn Traynor, Cameron L. McPhail
  • SALT FORM AND COCRYSTALS OF ADEFOVIR DIPIVOXIL AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20090247749
    Abstract: The present invention is directed to novel crystalline forms of adefovir dipivoxil and salts thereof.
    Type: Application
    Filed: March 31, 2008
    Publication date: October 1, 2009
    Inventors: Peter Garth Blazecka, Daqing Che, Cameron L. McPhail, Allan W. Rey
  • Amorphous ziprasidone hydrochloride (5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride) and processes to produce the same
    Publication number: 20090030204
    Abstract: The present invention relates to a new and useful amorphous form of ziprasidone hydrochloride (5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride) and preparations thereof.
    Type: Application
    Filed: December 6, 2007
    Publication date: January 29, 2009
    Inventors: Carlos Zetina-Rocha, Allan W. Rey, Matthew A. Buck, Lotfi Derdour, Stephen E. Horne, K.S. Keshava Murthy
  • Atorvastatin calcium propylene glycol solvates
    Publication number: 20080177087
    Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.
    Type: Application
    Filed: June 14, 2007
    Publication date: July 24, 2008
    Inventors: K.S. Keshava Murthy, Yajun Zhao, Allan W. Rey, Daqing Che, David A. Stradiotto, Uma Kotipalli
  • Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
    Publication number: 20080139508
    Abstract: A novel form of Ibandronate sodium which is particularly suitable for pharmaceutical applications, and a process for preparing said novel form.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 12, 2008
    Inventors: David A. Stradiotto, Allan W. Rey, Probal Kanti Datta, Krista Lyn Traynor, Cameron L. McPhail
  • Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
    Publication number: 20080139845
    Abstract: A novel form of Ibandronate sodium which is particularly suitable for pharmaceutical applications, and a process for preparing said novel form.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 12, 2008
    Inventors: David A. Stradiotto, Allan W. Rey, Probal Kanti Datta, Krista Lyn Traynor, Cameron L. McPhail
  • Process for the preparation of zonisamide and the intermediates thereof
    Patent number: 7375233
    Abstract: The present invention provides a novel and improved process for the preparation of Zonisamide and the intermediates thereof.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: May 20, 2008
    Assignee: Apotex Pharmachem Inc.
    Inventors: Gamini Weeratunga, Eckardt C. G. Wolf, Nageib Mohamed, Allan W. Rey, Bhaskar Reddy Guntoori
  • Preparation of 4-(4-fluorophenyl)-N-alkylnipecotinate esters, 4-(4-fluorophenyl)-N-arylnipecotinate esters and 4-(4-fluorophenyl)-N-aralkylnipecotinate esters
    Patent number: 7138523
    Abstract: A process for the industrial scale manufacture of 4-(4-fluorophenyl)-N-alkylnipecotinate esters by the addition of 4-fluorophenylmagnesium halide in tetrahydrofuran to 3,4-unsaturated-3-piperidine esters.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: November 21, 2006
    Assignee: Apotex Pharmachem Inc.
    Inventors: Allan W. Rey, K. S. Keshava Murthy, Bruno K. Radatus, Yajun Zhao, Tania E. Nish
  • Preparation of an anhydrate form of 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride (ziprasidone hydrochloride)
    Patent number: 7087611
    Abstract: The present invention relates to new and useful processes for the preparation of the anhydrate form of 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride.
    Type: Grant
    Filed: August 30, 2004
    Date of Patent: August 8, 2006
    Assignee: Apotex Pharmachem Inc.
    Inventors: Carlos Zetina-Rocha, Allan W. Rey, Stephen E. Horne
  • Preparation of 4-(4-fluorophenyl)-N-alkylnipecotinate esters, 4-(4-fluorophenyl)-N-arylnipecotinate esters and 4-(4-fluorophenyl)-N-aralkylnipecotinate esters
    Publication number: 20030220370
    Abstract: A process for the industrial scale manufacture of 4-(4-fluorophenyl)-N-alkylnipecotinate esters by the addition of 4-fluorophenylmagnesium halide in tetrahydrofuran to 3,4-unsaturated-3-piperidine esters.
    Type: Application
    Filed: May 17, 2002
    Publication date: November 27, 2003
    Inventors: Allan W. Rey, K.S. Keshava Murthy, Bruno K. Radatus, Yajun Zhao, Tania E. Nish
  • Preparation of 1,2,5,6-tetra-hydro-3-carboalkoxypridines such as arecoline and salts of 1,2,5,6-tetrahydro-3-carboalkoxypridines and arecoline hydrobromide
    Patent number: 6132286
    Abstract: A process is provided for the preparation of 1,2,5,6-tetrahydro-3-carboalkoxypyridines of formula (III) ##STR1## wherein R is a straight or cyclic substituted or unsubstituted alkyl chain having 1 to 6 carbon atoms, phenyl C.sub.1-6 alkyl, menthol or a derivative of menthol, or a derivative of camphor, and R' is an alkyl chain having 1 to 4 carbon atoms or phenyl C.sub.1-6 alkyl comprising reacting an alkyl pyridinium salt of formula ##STR2## wherein R and R' are as defined above and X is a suitable leaving group with sodium triacetoxyborohydride in the presence of an acid.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: October 17, 2000
    Assignee: Brantford Chemicals Inc.
    Inventors: K. S. Keshave Murthy, Allan W. Rey, Dan S. Matu
  • N-substituted 2-azetidinones
    Patent number: 6008347
    Abstract: The present invention provides novel cis-N-iminomethyl-3,4-disubstituted-2-azetidinones, and their use in the preparation of N-acyl-2-azetidinones, intermediates in the semi-synthesis of taxol and taxol derivatives.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: December 28, 1999
    Assignee: Bristol-Myers Squibb Company
    Inventors: Allan W. Rey, Purushotham Vemishetti, Roberto Droghini
  • Stereoselective and useful preparation of 3-substituted 4-aryl piperidine compounds
    Patent number: 5962689
    Abstract: This invention relates to new stereoselective processes for preparing 3-substituted-4-aryl piperidines and methods for controlling the absolute stereochemistry at the C-3 and C-4 positions of the piperidine ring. Compounds of this type are key intermediates in the preparation of paroxetine, femoxetine, and other medicaments.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: October 5, 1999
    Assignee: Brantford Chemicals Inc.
    Inventors: K. S. Keshava Murthy, Allan W. Rey
  • N-substituted 2-azetidinones
    Patent number: 5412092
    Abstract: Novel cis compound having the formula: ##STR1## wherein R.sup.1 is alkyl, haloalkyl, cycloalkyl, aryl or a carbohydrate derivative; X is O, N, S, C(O)O or a direct bond; and R.sup.2 is aryl, substituted aryl or heteroaryl are useful in the synthesis of taxol and taxol derivatives.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: May 2, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Allan W. Rey, Purushotham Vemishetti, Roberto Droghini