Patents by Inventor Allan Watkinson
Allan Watkinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9616117Abstract: An anthrax vaccine with alhydrogel as the adjuvant is presented in a composition formulated by mixing rPA with colloidal alhydrogel (alum) adjuvant to produce the final product, comprising 200 ?g/ml rPA bound to 0.26% alhydrogel in phosphate buffered saline (PBS), said formulation containing an optimal concentration of phosphate. Methods of using the vaccines to treat or prevent infections are also presented.Type: GrantFiled: October 2, 2009Date of Patent: April 11, 2017Assignee: PharmAthene, Inc.Inventors: Allan Watkinson, David Woodhouse, Robert Wilson
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Publication number: 20110236425Abstract: An anthrax vaccine with alhydrogel as the adjuvant is presented in a composition formulated by mixing rPA with colloidal alhydrogel (alum) adjuvant to produce the final product, comprising 200 ?g/ml rPA bound to 0.26% alhydrogel in phosphate buffered saline (PBS), said formulation containing an optimal concentration of phosphate. Methods of using the vaccines to treat or prevent infections are also presented.Type: ApplicationFiled: October 2, 2009Publication date: September 29, 2011Inventors: Allan Watkinson, David Woodhouse, Robert Wilson
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Publication number: 20100183675Abstract: A stable lyophilized protein formulation containing recombinant Protective Antigen (rPA) is described that can be reconstituted with a suitable diluent to generate a high potency protein concentration reconstituted formulation which is suitable for use as a vaccine against anthrax infection in mammals, especially human beings. These formulations were prepared by lyophilizing rPA in the presence of a reducing sugar, such as trehalose, and methods of such lyophilization are described. The resulting lyophilized mixture or composition is subsequently reconstituted to high immunogenicity without apparent loss of stability of the rPA protein. Methods of using said formulations in vaccination are also described.Type: ApplicationFiled: January 22, 2009Publication date: July 22, 2010Inventors: Allan Watkinson, Matthew Duchars
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Publication number: 20100029778Abstract: Hair and/or scalp treatment compositions comprise an antidandruff agent, an effective amount of a cannabinoid receptor (CBR) activating agent and a cosmetically acceptable diluent or carrier. Alternatively, the compositions may be shampoo compositions comprising from 3 to 50 wt % surfactant, a CB receptor activating agent and a cosmetically acceptable diluent or carrier, provided that the CB receptor activating agent is not palmitoylethanolamide. The compositions are useful in the treatment and/or prevention of the symptoms of dandruff and can reduce scalp itch, a symptom which is typically associated with dandruff.Type: ApplicationFiled: October 6, 2009Publication date: February 4, 2010Applicant: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Peter Lawrence BAILEY, Christopher John LITTLE, Francis MCGLONE, Roman RUKWIED, Allan WATKINSON
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Publication number: 20090317919Abstract: A method for assaying an antigen adsorbed on a solid support is provided. The method comprises: a) contacting a suspension of the antigen adsorbed on the solid support with a solution or suspension of an optionally detectably-labelled primary antibody to the antigen to form a solid-supported antigen-antibody complex; b) where the primary antibody is detectably labelled, optionally measuring the detectable label thereby to determine the quantity of the antigen; or c) contacting the solid-supported antigen-antibody complex with a detectably-labelled probe for the solid-supported antigen-antibody complex; and d) measuring the detectable label on the probe, thereby to determine the quantity of antigen. The antigen is preferably a component of a sub-unit vaccine, and most preferably anthrax protective antigen.Type: ApplicationFiled: April 12, 2007Publication date: December 24, 2009Inventors: Allan Watkinson, Robert Wilson, Steven Douglass, James Philip Myers
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Patent number: 7238343Abstract: Hair removal, especially from armpits damages skin, for example by irritating it, and this can be exacerbated by the application of antiperspirants to control body odour generation. In the present invention, the deleterious effects of hair removal, eg shaving, and antiperspirancy can be ameliorated by employing antiperspirant compositions containing a natural oil and glycerol to a combined concentration of from 1.5 to 15% by weight and in a weight ratio of from 4:1 to 1:4.Type: GrantFiled: December 11, 2003Date of Patent: July 3, 2007Assignee: Unilever Home & Personal Care USA division of Conopco, Inc.Inventors: Robert Stanley Lee, Allan Watkinson
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Publication number: 20040120909Abstract: Hair removal, especially from armpits damages skin, for example by irritating it, and this can be exacerbated by the application of antiperspirants to control body odour generation. In the present invention, the deleterious effects of hair removal, eg shaving, and antiperspirancy can be ameliorated by employing antiperspirant compositions containing a natural oil and glycerol to a combined concentration of from 1.5 to 15% by weight and in a weight ratio of from 4:1 to 1:4.Type: ApplicationFiled: December 11, 2003Publication date: June 24, 2004Applicant: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Robert Stanley Lee, Allan Watkinson
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Patent number: 6713051Abstract: Antiperspirant compositions comprising an astringent aluminum or zirconium salt can suffer from perceived irritancy when applied topically, which can be ameliorated or overcome by incorporating within the composition a PPAR activating fatty acid and/or hydrolyzable precursor thereof such as a triglyceride or ester of the PPAR, especially in an amount selected in the range of from 0.5 to 10 wt %. The compositions advantageously comprise an activated aluminum salt or aluminum-zirconium glycine complex.Type: GrantFiled: June 18, 2002Date of Patent: March 30, 2004Assignee: Unilever Home & Personal Care USA division of Conopco, Inc.Inventors: Andrew Easson Mayes, Anthony Vincent Rawlings, Allan Watkinson
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Publication number: 20030049220Abstract: Hair and/or scalp treatment compositions comprise an antidandruff agent, an effective amount of a cannabinoid receptor (CBR) activating agent and a cosmetically acceptable diluent or carrier. Alternatively, the compositions may be shampoo compositions comprising from 3 to 50 wt % surfactant, a CB receptor activating agent and a cosmetically acceptable diluent or carrier, provided that the CB receptor activating agent is not palmitoylethanolamide. The compositions are useful in the treatment and/or prevention of the symptoms of dandruff and can reduce scalp itch, a symptom which is typically associated with dandruff.Type: ApplicationFiled: July 17, 2002Publication date: March 13, 2003Applicant: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Peter Lawrence Bailey, Christopher John Little, Francis McGlone, Roman Rukwied, Allan Watkinson
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Patent number: 6503492Abstract: Deodorant and antiperspirant compositions comprising an aluminium or aluminium-zirconium active can suffer from perceived irritancy when applied topically, which is generally manifested as an itch sensation. This irritancy can be ameliorated or overcome by incorporating within the composition a cannabanoid receptor (CBR) activating agent, and especially an amount selected in the range of from 0.25 to 10 wt %.Type: GrantFiled: February 19, 2002Date of Patent: January 7, 2003Assignee: Unilever Home & Personal Care USA, a division of Conopco, Inc.Inventors: Francis McGlone, Sarah Paterson, Anthony Vincent Rawlings, Roman Rukwied, Allan Watkinson
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Publication number: 20030003068Abstract: Antiperspirant compositions comprising an astringent aluminium or zirconium salt can suffer from perceived irritancy when applied topically, which can be ameliorated or overcome by incorporating within the composition a PPAR activating fatty acid and/or hydrolysable precursor thereof such as a triglyceride or ester of the PPAR, especially in an amount selected in the range of from 0.5 to 10 wt %.Type: ApplicationFiled: June 18, 2002Publication date: January 2, 2003Applicant: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Andrew Easson Mayes, Anthony Vincent Rawlings, Allan Watkinson
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Publication number: 20020182159Abstract: Deodorant and antiperspirant compositions comprising an aluminum or aluminum-zirconium active can suffer from perceived irritancy when applied topically, which is generally manifested as an itch sensation. This irritancy can be ameliorated or overcome by incorporating within the composition a cannabanoid receptor (CBR) activating agent, and especially an amount selected in the range of from 0.25 to 10 wt %.Type: ApplicationFiled: February 19, 2002Publication date: December 5, 2002Applicant: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Francis McGlone, Sarah Paterson, Anthony Vincent Rawlings, Roman Rukwied, Allan Watkinson
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Patent number: 6365175Abstract: Edible compositions containing petroselinic acid are used for the preparation of food compositions or food supplements that are used as anti-inflammatory compositions that inhibit the production of metabolites of arachidonic acid and/or reduces the formation of intracellular adhesion molecules or as anti-aging compositions with a positive impact on wrinkling, sagging, photodamaged skin, dry skin, flaky skin and age spots.Type: GrantFiled: December 22, 1999Date of Patent: April 2, 2002Assignee: Unilever Patent HoldingsInventors: Simon Alaluf, Martin Richard Green, Jonathan Richard Powell, Julia Sarah Rogers, Allan Watkinson, Frederick William Cain, Heng Long Hu, Anthony Vincent Rawlings
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Patent number: 6287553Abstract: A topical composition and cosmetic method for treating skin conditions selected form the group consisting of wrinkling, sagging, photodamaged skin, sensitive skin, dry skin, flaky skin, red skin, irritated skin, itchy skin and age spots, the composition comprising: (a) conjugated linoleic acid, and/or derivatives thereof comprising conjugated linoleic acid moieties, in which at least 50% by weight of the conjugated linoleic acid and/or moieties, is present as the cis 9 trans 11 isomer; and (b) a dermatologically acceptable carrier.Type: GrantFiled: December 13, 1999Date of Patent: September 11, 2001Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.Inventors: Simon Alaluf, Martin Richard Green, Clive Roderick Harding, Heng-Long Hu, Gerald Patrick McNeill, Jonathan Richard Powell, Anthony Vincent Rawlings, Julia Sarah Rogers, Allan Watkinson
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Patent number: 5665366Abstract: A composition for topical application to the skin for alleviation or prevention of dry flaky skin conditions, dandruff or ache comprising one or more stratum corneum trypsin-like enzymes. The composition may further comprise an additional enzyme selected from glycosidases, other proteases, lipases and mixtures thereof. Optional additional active ingredients include sunscreens, lipids, hydroxy carboxylic acids and ketocarboxylic acids.Type: GrantFiled: January 2, 1996Date of Patent: September 9, 1997Assignee: Elizabeth Arden Co., Division of Conopco, Inc.Inventors: Anthony Vincent Rawlings, Allan Watkinson
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Patent number: 5554366Abstract: A composition for topical application to the skin for alleviation or prevention of dry flaky skin condition, dandruff or acne comprising stratum corneum chymotrypsin-like enzyme.The composition may additionally comprise a second enzyme selected from glycosidases, other proteases, lipases and mixtures thereof.Type: GrantFiled: January 17, 1995Date of Patent: September 10, 1996Assignee: Elizabeth Arden Co., Division of Conopco, Inc.Inventors: Anthony V. Rawlings, Allan Watkinson
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Patent number: 5545402Abstract: A composition for topical application to the skin for alleviation or prevention of dry flaky skin condition, dandruff or acne comprising one or more stratum corneum thiol proteases. The composition may further comprise a mild reducing agent and/or an additional enzyme selected from glycosidases, other proteases, lipases and mixtures thereof. Optional additional active ingredients include sunscreens, lipids, hydroxy carboxylic acids and ketocarboxylic acids.Type: GrantFiled: September 12, 1994Date of Patent: August 13, 1996Assignee: Elizabeth Arden Co., Division of Conopco, Inc.Inventor: Allan Watkinson