Patents by Inventor Allen A. Fienberg
Allen A. Fienberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240041871Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: ApplicationFiled: October 4, 2023Publication date: February 8, 2024Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon MATES, Allen FIENBERG, Lawrence P. WENNOGLE
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Publication number: 20230355616Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson’s disease or any combinations.Type: ApplicationFiled: February 15, 2023Publication date: November 9, 2023Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon MATES, Allen FIENBERG, Lawrence P. WENNOGLE
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Patent number: 11464781Abstract: Compounds that inhibit phosphodiesterase 1 (PDE1) are useful to treat glaucoma or elevated intraocular pressure. The PDE1 inhibitors may be administered as monotherapy or in combination with additional intraocular-pressure lowering agents. In addition, the invention provides ophthalmic compositions comprising PDE 1 inhibitors and optionally one or more additional intraocular pressure-lowering agents. Topical and systemic therapy may be used.Type: GrantFiled: February 24, 2010Date of Patent: October 11, 2022Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Robert Davis, Allen Fienberg
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Publication number: 20220125791Abstract: Disclosed herein are novel drug eluting contact lenses configured to release one or more compounds that inhibit phosphodiesterase 1 (PDE1). The PDE1 inhibitors may be administered as monotherapy or in combination with additional pharmaceutical agents in the treatment of an ophthalmic disease, disorder or injury. Related methods of use and treatment are also disclosed.Type: ApplicationFiled: January 28, 2020Publication date: April 28, 2022Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Robert DAVIS, Allen A. FIENBERG
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Publication number: 20200405713Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: ApplicationFiled: July 6, 2020Publication date: December 31, 2020Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon MATES, Allen FIENBERG, Lawrence P. WENNOGLE
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Patent number: 10702522Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: GrantFiled: October 19, 2018Date of Patent: July 7, 2020Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon Mates, Allen Fienberg, Lawrence P. Wennogle
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Publication number: 20190183888Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: ApplicationFiled: October 19, 2018Publication date: June 20, 2019Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon MATES, Allen FIENBERG, Lawrence P. WENNOGLE
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Patent number: 10238660Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder, delusional disorder, mania, or bipolar disorder.Type: GrantFiled: June 4, 2018Date of Patent: March 26, 2019Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Allen A. Fienberg, Lawrence P. Wennogle, Sharon Mates
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Patent number: 10117867Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: GrantFiled: March 23, 2017Date of Patent: November 6, 2018Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon Mates, Allen Fienberg, Lawrence P. Wennogle
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Publication number: 20180280396Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder, delusional disorder, mania, or bipolar disorder.Type: ApplicationFiled: June 4, 2018Publication date: October 4, 2018Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Allen A. FIENBERG, Lawrence P. WENNOGLE, Sharon MATES
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Patent number: 10010553Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder, delusional disorder, mania, or bipolar disorder.Type: GrantFiled: September 12, 2016Date of Patent: July 3, 2018Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Allen A. Fienberg, Lawrence P. Wennogle, Sharon Mates
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Publication number: 20170189398Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: ApplicationFiled: March 23, 2017Publication date: July 6, 2017Applicant: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon MATES, Allen FIENBERG, Lawrence P. WENNOGLE
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Patent number: 9616061Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: GrantFiled: October 16, 2015Date of Patent: April 11, 2017Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon Mates, Allen Fienberg, Lawrence Wennogle
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Publication number: 20160375028Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder, delusional disorder, mania, or bipolar disorder.Type: ApplicationFiled: September 12, 2016Publication date: December 29, 2016Inventors: Allen A. Fienberg, Lawrence P. Wennogle, Sharon Mates
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Patent number: 9468637Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder, delusional disorder, mania, or bipolar disorder.Type: GrantFiled: May 13, 2010Date of Patent: October 18, 2016Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Allen A. Fienberg, Lawrence P. Wennogle, Sharon Mates
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Publication number: 20160030425Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: ApplicationFiled: October 16, 2015Publication date: February 4, 2016Inventors: Sharon MATES, Allen FIENBERG, Lawrence WENNOGLE
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Patent number: 9198924Abstract: The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment and/or prophylaxis of narcolepsy.Type: GrantFiled: November 13, 2007Date of Patent: December 1, 2015Assignee: INTRA-CELLULAR THERAPIES, INC.Inventors: Sharon Mates, Allen A. Fienberg
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Patent number: 9168258Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: GrantFiled: October 30, 2013Date of Patent: October 27, 2015Assignee: INTRA-CELLULAR THERAPRIES, INC.Inventors: Sharon Mates, Allen Fienberg, Lawrence P. Wennogle
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Patent number: 9006258Abstract: The present invention relates to a new use for compounds that inhibit phosphodiesterase 1 (PDE1), e.g., that inhibit PDE1-mediated suppression of the dopamine D1 receptor and/or progesterone signaling pathways, including, e.g., methods of treatment or prophylaxis for conditions which may be ameliorated by enhancing the progesterone signaling response, particularly female sexual dysfunction.Type: GrantFiled: December 5, 2007Date of Patent: April 14, 2015Assignee: Intra-Cellular Therapies, Inc.Inventors: Allen A. Fienberg, Sharon Mates, Lawrence P. Wennogle
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Patent number: RE48839Abstract: Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.Type: GrantFiled: February 6, 2020Date of Patent: December 7, 2021Assignee: Intra-Cellular Therapies, IncInventors: Sharon Mates, Allen Fienberg, Lawrence Wennogle