Patents by Inventor Allen C. Steere

Allen C. Steere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190137491
    Abstract: Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with P. copri or a portion thereof. In one aspect of the invention the immunological reactivity of the subject to one or more protein of P. copri or polypeptide fragments thereof such as protein Pc-p27 or polypeptide fragments thereof, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays and kits for use with the methods are also disclosed.
    Type: Application
    Filed: June 6, 2017
    Publication date: May 9, 2019
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Allen C. Steere, Elise E. Drouin
  • Publication number: 20180156778
    Abstract: Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with N-acetylglucosamine-6-sulfatase and/or filamin-A, wherein immunological reactivity of the subject to one or more of N-acetylglucosamine-6-sulfatase or filamin-A, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays and kits for use with the methods are also disclosed.
    Type: Application
    Filed: May 12, 2016
    Publication date: June 7, 2018
    Applicant: THE GENERAL HOSPITAL CORPORATION d/b/a MASSACHUSETTS GENERAL HOSPITAL
    Inventors: Allen C. Steere, Elise E. Drouin
  • Publication number: 20150219646
    Abstract: The invention is directed to methods of assaying biological samples for the presence of antibodies or antigens indicative of infection by a bacterium of the Borrelia burgdorferi sensu lato complex. Also included in the invention are devices that can be used in carrying out these methods. The methods and devices may be used to help identify subjects that have Lyme disease.
    Type: Application
    Filed: August 15, 2013
    Publication date: August 6, 2015
    Applicant: The General Hositpal Corporaion
    Inventors: John A. Branda, Mary Jane Ferraro, Allen C. Steere
  • Publication number: 20130302329
    Abstract: The present invention provides for methods and compositions for identifying and detecting autoantigens. Candidate autoantigens are identified by obtaining a subject sample from which HLA-DR-presented peptides are collected and identified using mass spectometry, then synthesized and reacted with the same subject peripheral blood or effected tissue. In particular, the present invention provides for endothelial cell growth factor as a novel autoantigen biomarker for Lyme disease-associated arthritis.
    Type: Application
    Filed: September 21, 2011
    Publication date: November 14, 2013
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Allen C. Steere, Elise Drouin, Catherine Costello, Robert Seward