Patents by Inventor Allen Cato
Allen Cato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240398917Abstract: Provided are methods for preventing initiation and/or progression of gastrin-associated tumors and/or cancers in subjects. In some embodiments, the methods relate to administering compositions that gastrin immunogens to subjects. Also provided are methods for inhibiting development of gastrin-associated precancerous lesions, methods for preventing formation of fibrosis associated with a tumor and/or a cancer, uses of compositions that include a gastrin immunogen to prevent initiation and/or development of a gastrin-associated tumor or cancer and/or for preparing medicaments therefor, and compositions for use in preventing initiation and/or development of gastrin-associated tumors and/or cancers and/or precancerous lesions thereof.Type: ApplicationFiled: January 13, 2022Publication date: December 5, 2024Applicant: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Allen Cato, Teresa Phillips
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Patent number: 12150978Abstract: Provided are methods for preventing initiation and/or progression of gastrin-associated tumors and/or cancers in subjects. In some embodiments, the methods relate to administering compositions that gastrin immunogens to subjects. Also provided are methods for inhibiting development of gastrin-associated precancerous lesions, methods for preventing formation of fibrosis associated with a tumor and/or a cancer, uses of compositions that include a gastrin immunogen to prevent initiation and/or development of a gastrin-associated tumor or cancer and/or for preparing medicaments therefor, and compositions for use in preventing initiation and/or development of gastrin-associated tumors and/or cancers and/or precancerous lesions thereof.Type: GrantFiled: January 13, 2021Date of Patent: November 26, 2024Assignee: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Allen Cato, Teresa Phillips
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Patent number: 12076383Abstract: Provided are methods for sensitizing gastrin-associated tumors and/or cancers in subjects to inducers of humoral and cellular immune responses. In some embodiments, the methods relate to administering compositions that have anti-gastrin antibodies, gastrin peptides, and/or nucleic acids that inhibit expression of gastrin gene products to subjects. Also provided are methods for preventing, reducing, and/or eliminating the formation of fibroses associated with tumors and/or cancers, and methods for treating gastrin-associated tumors and/or cancers that include administering to subjects in need thereof a first agent that provides and/or induces an anti-gastrin humoral or cellular immune response in the subject and a second agent that includes one or more stimulators of cellular immune responses against the tumors and/or cancers.Type: GrantFiled: November 18, 2022Date of Patent: September 3, 2024Assignee: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Nicholas Osborne, Brian E. Huber, Allen Cato
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Publication number: 20230398196Abstract: Provided are methods for enhancing anti-tumor and/or anti-cancer immunotherapies. In some embodiments, the methods include administering to a subject in need thereof a composition that includes a conjugate that includes a gastrin immunogen conjugated to an immunogenic carrier, optionally conjugated via a linker, in an amount and via a route sufficient to enhance entry into the tumor and/or cancer of an anti-tumor T cell, whereby an anti- and/or anti-cancer tumor immunotherapy is enhanced. Also provided are pharmaceutical compositions that have the conjugates for use in treating tumors and cancers, methods for treating tumors and/or cancers, and methods for sensitizing solid tumors and/or cancers in subjects to chimeric antigen receptor-T (CAR-T) cell therapies.Type: ApplicationFiled: November 8, 2021Publication date: December 14, 2023Applicants: Cancer Advances Inc., Georgetown UniversityInventors: Allen Cato, Lynda Sutton, Jill P. Smith
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Publication number: 20230086898Abstract: Provided are methods for sensitizing gastrin-associated tumors and/or cancers in subjects to inducers of humoral and cellular immune responses. In some embodiments, the methods relate to administering compositions that have anti-gastrin antibodies, gastrin peptides, and/or nucleic acids that inhibit expression of gastrin gene products to subjects. Also provided are methods for preventing, reducing, and/or eliminating the formation of fibroses associated with tumors and/or cancers, and methods for treating gastrin-associated tumors and/or cancers that include administering to subjects in need thereof a first agent that provides and/or induces an anti-gastrin humoral or cellular immune response in the subject and a second agent that includes one or more stimulators of cellular immune responses against the tumors and/or cancers.Type: ApplicationFiled: November 18, 2022Publication date: March 23, 2023Applicant: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Nicholas Osborne, Brian E. Huber, Allen Cato
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Patent number: 11583576Abstract: Provided are methods for sensitizing gastrin-associated tumors and/or cancers in subjects to inducers of humoral and cellular immune responses. In some embodiments, the methods relate to administering compositions that have anti-gastrin antibodies, gastrin peptides, and/or nucleic acids that inhibit expression of gastrin gene products to subjects. Also provided are methods for preventing, reducing, and/or eliminating the formation of fibroses associated with tumors and/or cancers, and methods for treating gastrin-associated tumors and/or cancers that include administering to subjects in need thereof a first agent that provides and/or induces an anti-gastrin humoral or cellular immune response in the subject and a second agent that includes one or more stimulators of cellular immune responses against the tumors and/or cancers.Type: GrantFiled: June 15, 2018Date of Patent: February 21, 2023Assignee: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Nicholas Osborne, Brian E. Huber, Allen Cato
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Publication number: 20210275649Abstract: Provided are methods for preventing initiation and/or progression of gastrin-associated tumors and/or cancers in subjects. In some embodiments, the methods relate to administering compositions that gastrin immunogens to subjects. Also provided are methods for inhibiting development of gastrin-associated precancerous lesions, methods for preventing formation of fibrosis associated with a tumor and/or a cancer, uses of compositions that include a gastrin immunogen to prevent initiation and/or development of a gastrin-associated tumor or cancer and/or for preparing medicaments therefor, and compositions for use in preventing initiation and/or development of gastrin-associated tumors and/or cancers and/or precancerous lesions thereof.Type: ApplicationFiled: January 13, 2021Publication date: September 9, 2021Applicant: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Allen Cato, Teresa Phillips
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Publication number: 20200206332Abstract: Provided are methods for sensitizing gastrin-associated tumors and/or cancers in subjects to inducers of humoral and cellular immune responses. In some embodiments, the methods relate to administering compositions that have anti-gastrin antibodies, gastrin peptides, and/or nucleic acids that inhibit expression of gastrin gene products to subjects. Also provided are methods for preventing, reducing, and/or eliminating the formation of fibroses associated with tumors and/or cancers, and methods for treating gastrin-associated tumors and/or cancers that include administering to subjects in need thereof a first agent that provides and/or induces an anti-gastrin humoral or cellular immune response in the subject and a second agent that includes one or more stimulators of cellular immune responses against the tumors and/or cancers.Type: ApplicationFiled: June 15, 2018Publication date: July 2, 2020Applicant: Cancer Advances Inc.Inventors: Lynda Sutton, Jill P. Smith, Nicholas Osborne, Brian E. Huber, Allen Cato
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Publication number: 20100133924Abstract: Disclosed herein are methods and apparatus for a guided single-phase or multi-phase linear motor actuator with a snap-together design. Some embodiments include the ability to monitor and/or adjust work being done, yet with a cost that is comparable to that of cams or pneumatic devices. In one embodiment, a coil is attached to a bobbin assembly that is secured behind a piston. To prevent rotation of the piston during operation, a spline bearing may be slidably fitted onto one or more grooves of a spline shaft disposed within the piston assembly. One or more cylindrical magnets surrounding the coil actuate the piston based upon the direction that current is traveling through the coil. Since the electromotive force generated is linear with respect to the spline shaft, unwanted lateral force acting upon the spline shaft can be reduced and/or eliminated.Type: ApplicationFiled: November 19, 2009Publication date: June 3, 2010Inventors: Edward August NEFF, Toan Minh Vu, Karl Gene Stocks, David Dehe Huang, Naoyuki Okada, Tiep Trung Le, Gary Joseph Ring, Mark Allen Cato, Jaime Sandoval Ruiz