Patents by Inventor Allen Duplantier

Allen Duplantier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors for coronavirus
    Patent number: 11963959
    Abstract: Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: April 23, 2024
    Assignees: Southwest Research Institute, The Government of the United States, as represented by The Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Jonathan A. Bohmann, Nadean M. Gutierrez, Joseph A. Mcdonough, Robert Francis Campbell, Michael Gordon Joyce, Rekha Panchal, Rajeshwer Sankhala, Allen Duplantier
  • Antiviral drugs targeting the N-terminal domain (NTD) of the coronavirus spike receptor binding domain (RBD)
    Patent number: 11865111
    Abstract: Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: January 9, 2024
    Assignees: Southwest Research Institute, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Government of the United States, as Represented by the Secretary of the Army
    Inventors: Jonathan A. Bohmann, Nadean M. Gutierrez, Joseph A. McDonough, Robert Francis Campbell, Michael Gordon Joyce, Rekha Panchal, Rajeshwer Sankhala, Allen Duplantier
  • ANTIVIRAL DRUGS TARGETING THE N-TERMINAL DOMAIN (NTD) OF THE CORONAVIRUS SPIKE RECEPTOR BINDING DOMAIN (RBD)
    Publication number: 20230074535
    Abstract: Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 9, 2023
    Inventors: Jonathan A. BOHMANN, Nadean M. GUTIERREZ, Joseph A. MCDONOUGH, Robert Francis CAMPBELL, Michael Gordon JOYCE, Rekha PANCHAL, Rajeshwer SANKHALA, Allen DUPLANTIER
  • INHIBITORS FOR CORONAVIRUS
    Publication number: 20230065024
    Abstract: Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 2, 2023
    Inventors: Jonathan A. BOHMANN, Nadean M. GUTIERREZ, Joseph A. MCDONOUGH, Robert Francis CAMPBELL, Michael Gordon JOYCE, Rekha PANCHAL, Rajeshwer SANKHALA, Allen DUPLANTIER
  • Benzamide Inhibitors of The P2X7 Receptor
    Publication number: 20070281939
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1-R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: January 8, 2007
    Publication date: December 6, 2007
    Inventors: Mark Dombrowski, Allen Duplantier
  • Benzamide Inhibitors of the P2X7 Receptor
    Publication number: 20070142329
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1-R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: February 9, 2007
    Publication date: June 21, 2007
    Inventors: Mark Dombroski, Allen Duplantier, Chakrapani Subramanyam
  • Benzamide inhibitors of the P2X7 receptor
    Publication number: 20060217430
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1-R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: March 23, 2006
    Publication date: September 28, 2006
    Inventors: Mark Dombroski, Allen Duplantier, Chakrapani Subramanyam
  • Azabenzoxazoles for the treatment of CNS disorders
    Publication number: 20060173179
    Abstract: The present invention relates to ?7 nicotinic receptor agonists of formula I as described herein and to a method for treating disorders of the Central Nervous System (CNS) such as cognitive deficits in schizophrenia, by administering to a mammal an ?7 nicotinic receptor agonist of formula I.
    Type: Application
    Filed: November 14, 2005
    Publication date: August 3, 2006
    Inventors: Bruce Rogers, Allen Duplantier, Christopher O'Donnell, Lei Zhang, Alisher Khasanov
  • Azabenzoxazoles for the treatment of CNS disorders
    Publication number: 20060166974
    Abstract: The present invention relates to ?7 nicotinic receptor agonists of formula I as described herein and to a method for treating disorders of the Central Nervous System (CNS) such as cognitive deficits in schizophrenia, by administering to a mammal an ?7 nicotinic receptor agonist of formula I as shown herein.
    Type: Application
    Filed: November 11, 2005
    Publication date: July 27, 2006
    Inventors: Bruce Rogers, Allen Duplantier, Christopher O'Donnell, Lei Zhang
  • Benzamide, heteroarylamide and reverse amides
    Publication number: 20060058302
    Abstract: The present invention relates to novel to P2X7 inhibitors of formula I and to processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are potent inhibitors of P2X7 and as such are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: October 18, 2005
    Publication date: March 16, 2006
    Inventors: Allen Duplantier, Chakrapani Subramanyam
  • Benzamide inhibitors of the P2X, receptor
    Publication number: 20060040939
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1-R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: October 27, 2005
    Publication date: February 23, 2006
    Inventors: Mark Dombroski, Allen Duplantier
  • Benzamide inhibitors of the P2X7 receptor
    Publication number: 20050009900
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1-R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Application
    Filed: May 12, 2004
    Publication date: January 13, 2005
    Inventors: Mark Dombroski, Allen Duplantier, Chakrapani Subramanyam