Abstract: Methods, systems, and computer program products are provided for enabling selective file system access by applications. An application is installed in a computing device. An application manifest associated with the application is received. The application manifest indicates one or more file types that the application is allowed to access. The indicated file type(s) are registered in a location accessible by a broker service. The application is launched as an application process. The application process is isolated in an application container. The application container prevents direct access by the application process to file system data. An access request related to first data of the file system data is received at the broker service from the application process. Access by the application process to the first data is enabled when the broker service determines that a file type of the first data is included in the registered file type(s).

Abstract: An apparatus and method for encoding data are disclosed that may allow for performing periodic calibration operations on a communication link. A controller may determine multiple possible values for a reference voltage used with the communication link based on an initial value. Calibration operations may be performed using each possible value, and the results of the operations scored based on the width of data eyes measured during the calibration operations. The controller may then select a new value for the reference voltage from the multiple possible values dependent upon the scores of each of the multiple possible values.

Abstract: Disclosed is a method for determining the turnover rate of biomolecules in a subject, which include administering to the subject, 2H20 in an amount sufficient to label biomolecules in the subject with 2H. Samples are collected from the subject at one or more time points and isotopomers are detected for the labeled biomolecules in the samples. The fractional abundance is determined for the isotopomers of the biomolecules in the samples and the biomolecule turnover rates of the one or more labeled biomolecules is determined based on the fractional abundance of the isotopomers. A computer-implemented method is also disclosed for determining the turnover rate of one or more biomolecules in subject. In certain other embodiments, a system for determining protein turnover rates in a subject is also provided. Also provided in certain embodiments is a computer program product for determining protein turnover rates in a subject.

Abstract: Methods, systems, and computer program products are provided for enabling selective file system access by applications. An application is installed in a computing device. An application manifest associated with the application is received. The application manifest indicates one or more file types that the application is allowed to access. The indicated file type(s) are registered in a location accessible by a broker service. The application is launched as an application process. The application process is isolated in an application container. The application container prevents direct access by the application process to file system data. An access request related to first data of the file system data is received at the broker service from the application process. Access by the application process to the first data is enabled when the broker service determines that a file type of the first data is included in the registered file type(s).