Patents by Inventor Allen Yi

Allen Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10426850
    Abstract: The present invention provides both a caged collagen mimetic peptide (CCMP) having the formula: L-S-Zm-[Gly-X-Y]n-LGly-X-Y-[Gly-X-Y]n (SEQ ID NO: 19); wherein L is one or more detectable moieties; S is one or more spacer molecules; Zm is any amino acid where m is an integer of 1 to 10; X is proline or modified proline; Y is proline or modified proline; Gly is glycine; n is an integer from 1 to 20; and LGly is a glycine covalently linked to a cage moiety comprising a labile protecting group, as well as a collagen mimetic peptides lacking the labile protecting group (CMP). The inventions are useful for binding collagen and denatured collagen and/or gelatin both in vitro and in vivo, and are useful for targeting any organ or tissue where collagen is present, and can be used for research and diagnostic imaging (both in vivo and in vitro) and also for in vivo therapeutic applications.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: October 1, 2019
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Michael S. Yu, Yang Li, Daniel Summerfield, Allen Yi-Lan Wang, Catherine A. Foss, Martin G. Pomper
  • Publication number: 20150111308
    Abstract: The invention provides modified collagen and related therapeutic and diagnostic methods.
    Type: Application
    Filed: October 13, 2014
    Publication date: April 23, 2015
    Inventors: Michael Yu, Jennifer H. Elisseeff, Hyeseung Janice Lee, Xiao Mo, Allen Yi-Lan Wang
  • Patent number: 8883964
    Abstract: The invention provides modified collagen and related therapeutic and diagnostic methods.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: November 11, 2014
    Assignee: The Johns Hopkins University
    Inventors: Michael Yu, Jennifer H. Elisseeff, Allen Yi-Lan Wang, Hyeseung Janice Lee, Xiao Mo
  • Patent number: 8283414
    Abstract: The invention provides modified collagen and related therapeutic and diagnostic methods.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: October 9, 2012
    Assignee: The Johns Hopkins University
    Inventors: Michael Yu, Jennifer H. Elisseeff, Hyeseung Janice Lee, Xiao Mo, Allen Yi-Lan Wang
  • Patent number: 6739523
    Abstract: A shower head having a plurality of spray modes and unique controls to allow the selection of the desired mode. The shower head includes several unique features to allow the inclusion of several different spray modes, such as wide spray, medium spray, center spray, champagne spray, high speed pulsating spray, low speed pulsating spray, and mist. A waterfall mode can be implemented. The shower head includes a flow control valve that controls the pressure of the water flow, and acts to divert water to a mode selector or to a separate spray mode, such as the mist mode. The flow control valve diverts water between the mode selector and the separate spray mode. It also allows a combination of the modes controlled by the mode selector and the separate spray mode. The shower head also includes a mode selector. The mode selector transfers or routes fluids from the flow control valve to any number of individual or a combination of flow spray mode outlets.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: May 25, 2004
    Assignee: Water Pik, Inc.
    Inventors: Jay A. Haverstraw, Joseph W. Cacka, Robin D. Harris, Robert B. Male, Gary J. Thomas, Allen Yi
  • Publication number: 20030121993
    Abstract: A shower head having a plurality of spray modes and unique controls to allow the selection of the desired mode. The shower head includes several unique features to allow the inclusion of several different spray modes, such as wide spray, medium spray, center spray, champagne spray, high speed pulsating spray, low speed pulsating spray, and mist. A waterfall mode can be implemented. The shower head includes a flow control valve that controls the pressure of the water flow, and acts to divert water to a mode selector or to a separate spray mode, such as the mist mode. The flow control valve diverts water between the mode selector and the separate spray mode. It also allows a combination of the modes controlled by the mode selector and the separate spray mode.
    Type: Application
    Filed: September 23, 2002
    Publication date: July 3, 2003
    Inventors: Jay A. Haverstraw, Joseph W. Cacka, Robin D. Harris, Robert B. Male, Gary J. Thomas, Allen Yi
  • Patent number: 6454186
    Abstract: A shower head having a plurality of spray modes and unique controls to allow the selection of the desired mode. The shower head includes several unique features to allow the inclusion of several different spray modes, such as wide spray, medium spray, center spray, champagne spray, high speed pulsating spray, low speed pulsating spray, and mist. A waterfall mode can be implemented. The shower head includes a flow control valve that controls the pressure of the water flow, and acts to divert water to a mode selector or to a separate spray mode, such as the mist mode. The flow control valve diverts water between the mode selector and the separate spray mode. It also allows a combination of the modes controlled by the mode selector and the separate spray mode. The shower head also includes a mode selector. The mode selector transfers or routes fluids from the flow control valve to any number of individual or a combination of flow spray mode outlets.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: September 24, 2002
    Assignee: Water Pik, Inc.
    Inventors: Jay A. Haverstraw, Joseph W. Cacka, Robin D. Harris, Robert B. Male, Gary J. Thomas, Allen Yi
  • Publication number: 20010023901
    Abstract: A shower head having a plurality of spray modes and unique controls to allow the selection of the desired mode. The shower head includes several unique features to allow the inclusion of several different spray modes, such as wide spray, medium spray, center spray, champagne spray, high speed pulsating spray, low speed pulsating spray, and mist. A waterfall mode can be implemented. The shower head includes a flow control valve that controls the pressure of the water flow, and acts to divert water to a mode selector or to a separate spray mode, such as the mist mode. The flow control valve diverts water between the mode selector and the separate spray mode. It also allows a combination of the modes controlled by the mode selector and the separate spray mode. The shower head also includes a mode selector. The mode selector transfers or routes fluids from the flow control valve to any number of individual or a combination of flow spray mode outlets.
    Type: Application
    Filed: May 9, 2001
    Publication date: September 27, 2001
    Inventors: Jay A. Haverstraw, Joseph W. Cacka, Robin D. Harris, Robert B. Male, Gary J. Thomas, Allen Yi
  • Patent number: 6230989
    Abstract: A shower head having a plurality of spray modes and unique controls to allow the selection of the desired mode. The shower head includes several unique features to allow the inclusion of several different spray modes, such as wide spray, medium spray, center spray, champagne spray, high speed pulsating spray, low speed pulsating spray, and mist. A waterfall mode can be implemented. The shower head includes a flow control valve that controls the pressure of the water flow, and acts to divert water to a mode selector or to a separate spray mode, such as the mist mode. The flow control valve diverts water between the mode selector and the separate spray mode. It also allows a combination of the modes controlled by the mode selector and the separate spray mode. The shower head also includes a mode selector. The mode selector transfers or routes fluids from the flow control valve to any number of individual or a combination of flow spray mode outlets.
    Type: Grant
    Filed: August 25, 1999
    Date of Patent: May 15, 2001
    Assignee: Water Pik, Inc.
    Inventors: Jay A. Haverstraw, Joseph W. Cacka, Robin D. Harris, Robert B. Male, Gary J. Thomas, Allen Yi