Abstract: In embodiments, the present invention provides methods and systems for providing remote real-time guidance for a procedure with a device. The method and systems may include providing a user guidance application executing on a system during the procedure. The methods and systems may be enabled to receive voice commands, and may include providing a step-by-step guidance from a remote human specialist through the steps required to complete a procedure with a device. The systems and methods may include, displaying on the system, procedure reference material associated with the procedure and accessible to the user to assist the user in the use of the device.