Abstract: A tissue treating device includes a handle with an actuator; a control cable; and a cap. The cap includes a mounting structure removably coupled in an operative configuration on a distal end of an insertion device. The cap includes a part movably coupled to the structure for movement between a retracted position in which a distal end of the part is received over the distal end of the device and an extended position in which a distal end of the part extends distally beyond the distal end of the device. The part includes a wall defining an internal channel so that, when the part is in the extended position, the wall surrounds a space contiguous to the distal end of the device. The part is coupled to a distal end of the cable so that, actuation of the actuator moves the part between the extended and retracted positions.

Abstract: A device is for facilitating an over-the-scope application of a tissue treating element and includes an end cap and control members. The cap includes a proximal portion mounted over a distal end of a scope device and a distal portion including flaps. The proximal portion extends along a longitudinal axis from a proximal end to a distal end and includes a proximal channel extending therethrough. A proximal end of each flap is pivotally connected to the distal end of the proximal portion so that the flaps are movable between a closed configuration and an expanded configuration. A distal end of each of the members is connected to a corresponding flap so that a longitudinal movement of the members relative to the proximal portion of the cap moves the flaps relative to the proximal portion between the closed and expanded configurations.

Abstract: A medical device includes an insertion portion, a light-emitting optical fiber, and a light-receiving optical fiber. The insertion portion includes a shaft, and the shaft includes a sheath and an electrode. The sheath includes a sheath lumen, and the electrode is positioned within at least a distal portion of the sheath. The electrode includes an electrode lumen, and the electrode is configured to deliver energy to a target site. The light-emitting optical fiber is configured to deliver light to the target site. At least a portion of the light-emitting optical fiber is positioned within the sheath or the electrode lumen. The light-receiving optical fiber is configured to receive light from the target site. At least a portion of the light-receiving optical fiber is positioned within the electrode lumen.

Abstract: Devices, systems, and methods of or for use with an elongate shaft of a medical scope. The device may be or may include a cap for the elongate shaft. The cap may include a proximal end, a distal end, a lumen extending between the proximal end and the distal end, and a protrusion located between the proximal end and the distal end. The proximal end of the cap may be configured to couple with the elongate shaft. The distal end of the cap may define a first diameter. The protrusion may define a second diameter that is smaller than the first diameter. The protrusion may be configured to engage tissue received in the lumen through the distal end.

Abstract: An ostomy device includes an implant shaped in a ring and sized for placement in or adjacent to a hole in an abdominal wall, the implant including a surface for contacting a lumen. The implant includes a first part including the surface for contacting the lumen, the first part, when placed in or adjacent to the hole in the abdominal wall, extending in a direction orthogonal to the abdominal wall to support the lumen. The implant includes a region for attaching an ostomy bag.

Abstract: An ostomy device includes an implant formed of a flexible material and shaped so that the implant is capable of transitioning between a first shape and a second shape. The implant includes a tubular body sized and shaped for insertion within a lumen extending through a hole in an abdominal wall, a flared portion extending radially outward and away from the body when the implant is in the first shape, and a transition region between the body and the flared portion. The transition region and the flared portion are bendable so that transitioning the implant from the first shape into the second shape comprises inverting the flared portion so that a surface of the flared portion can be brought into contact with an outer surface of patient anatomy, whereupon the implant can be attached to the patient anatomy in the second shape.

Abstract: An ostomy bag device includes a bag with first and second chambers communicating via a first opening and a pressure sensitive interface. The bag includes a second opening interfacing with a stoma exit and receiving waste in the first chamber, a third opening expelling the waste from the first chamber, and a fourth opening releasing gas from the second chamber. The interface transitions from a first state in which the interface prevents a gas flow through the first opening from the first to second chambers and a second state in which the interface allows the flow. A first pressure differential in the first chamber relative to the second chamber causes the interface to assume the first state preventing the flow and a second pressure differential in the first chamber relative to the second chamber higher than the first differential causes the interface to assume the second state allowing the flow.

Abstract: A tissue treating device includes a handle with an actuator; a control cable; and a cap. The cap includes a mounting structure removably coupled in an operative configuration on a distal end of an insertion device. The cap includes a part movably coupled to the structure for movement between a retracted position in which a distal end of the part is received over the distal end of the device and an extended position in which a distal end of the part extends distally beyond the distal end of the device. The part includes a wall defining an internal channel so that, when the part is in the extended position, the wall surrounds a space contiguous to the distal end of the device. The part is coupled to a distal end of the cable so that, actuation of the actuator moves the part between the extended and retracted positions.

Abstract: Medical devices and related methods are described, including a medical device that includes a shaft including a working channel and a distal tip. The distal tip may include an assembly that includes an imaging device and an elevator. The assembly may be movable from a lowered configuration to an angled configuration to move the imaging device and the elevator from the lowered configuration to the angled configuration.

Abstract: A clip includes first and second jaws, first and second hinges, and a connection portion. Each of the jaws extends along a curve from a first end to a second end. The first hinge connects the first ends and the second hinge connects the second ends so that the jaws are movable between at open configuration, in which the jaws are separated from one another, and a closed configuration, in which the jaws are drawn toward one another to grip tissue therebetween. The first and/or second hinges is/are biased to draw the clip toward the closed configuration. The portion connects an end of each of the hinges to a corresponding one of the first and second ends. The connecting includes an engaging feature engaging via a through-the scope device to extract the clip from a tissue over which it has been clipped upon a deployment thereof.

Abstract: Compositions useful in medical procedures are described, such as separating tissue layers, e.g., submucosal tissue layers, for removal. In some examples, the compositions may include a pharmaceutically acceptable carrier fluid and one or more biocompatible materials at least partially or completely dissolved or suspended in the pharmaceutically acceptable carrier fluid. The one or more biocompatible materials may be chosen from polymers, phospholipids, nanoclays, or combinations thereof. Advantageously, the compositions may be formulated as a solution, emulsion, gel, or suspension capable of being injected into tissue.

Abstract: A device is for facilitating an over-the-scope application of a tissue treating element and includes an end cap and control members. The cap includes a proximal portion mounted over a distal end of a scope device and a distal portion including flaps. The proximal portion extends along a longitudinal axis from a proximal end to a distal end and includes a proximal channel extending therethrough. A proximal end of each flap is pivotally connected to the distal end of the proximal portion so that the flaps are movable between a closed configuration and an expanded configuration. A distal end of each of the members is connected to a corresponding flap so that a longitudinal movement of the members relative to the proximal portion of the cap moves the flaps relative to the proximal portion between the closed and expanded configurations.

Abstract: A medical device includes a handle, a shaft, an electrode, and at least one inflatable balloon. The handle includes an electrical connection and a balloon fluid port. The shaft extends from a distal portion of the handle. The electrode is positioned at a distal end of the shaft. The electrode is electrically connected to the electrical connection via one or more conductive elements extending through the handle and the shaft. The at least one inflatable balloon is positioned on a portion of shaft. The at least one inflatable balloon is fluidly coupled to the balloon fluid port via one or more tubes extending through the handle and the shaft.