Patents by Inventor Allister Fraser

Allister Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amine cationic lipids and uses thereof
    Patent number: 9549983
    Abstract: The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such as an amino-amine or an amino-amide moiety. The lipid compounds are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic payload or an antisense payload, such as an RNAi agent).
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: January 24, 2017
    Assignee: Dicerna Pharmaceuticals, Inc.
    Inventors: Bob Dale Brown, Sujit Kumar Basu, David A. Schwartz, Allister Fraser
  • Amine Cationic Lipids and Uses Thereof
    Publication number: 20140371293
    Abstract: The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such as an amino-amine or an amino-amide moiety. The lipid compounds are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic payload or an antisense payload, such as an RNAi agent).
    Type: Application
    Filed: April 17, 2014
    Publication date: December 18, 2014
    Applicant: Dicerna Pharmaceuticals, Inc.
    Inventors: Bob Dale Brown, Sujit Kumar Basu, David A. Schwartz, Allister Fraser
  • Serine hydrolase inhibitors
    Patent number: 7879846
    Abstract: Provided herein are benzoxazinone compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated diseases.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: February 1, 2011
    Assignee: Kyorin Pharmaceutical Co.., Ltd.
    Inventors: Kevin Shreder, Yi Hu, Allister Fraser, Yasushi Kohno, Akihiko Kojima, Junichi Ishiyama
  • Serine hydrolase inhibitors
    Publication number: 20080161290
    Abstract: Provided herein are benzoxazinone compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated diseases.
    Type: Application
    Filed: September 20, 2007
    Publication date: July 3, 2008
    Inventors: Kevin Shreder, Yi Hu, Allister Fraser, Yasushi Kohno, Akihiko Kojima, Junichi Ishiyama