Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell is deficient in at least one endogenous function, for instance cytotoxic activity. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.

Abstract: A cargo-carrying wheeled vehicle, said vehicle comprising: at least a cargo hold chassis (10); at least a rider support chassis (20) configured to be operatively behind said cargo hold chassis (10), in that, said cargo hold chassis (10) and said rider support chassis (20) cooperate to maintain centre of gravity of said vehicle, after addition of cargo to said cargo hold chassis (10) and after addition of rider to said rider support chassis (20), to obtain a naturally balanced position for said vehicle in a loaded as well as an unloaded condition.

Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.

Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.

Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.

Abstract: A steering mechanism for a vehicle, the vehicle comprising a cargo hold chassis (10), communicably coupled with a front wheel (10a) located on a front axle; and a rider and pillion support chassis (20), communicably coupled with a rear wheel (12a) located on a rear axle; wherein, the cargo hold chassis (10) is located operatively forward and operatively lower with respect to the rider support chassis (20); the mechanism comprising: a steering mechanism comprising a steering stem (30), a steering column rod (36), and a steering handle (32), the steering stem (30) mounted in an operative front of the cargo hold chassis (10), the steering handle (32) mounted operatively atop the cargo hold chassis (10); the steering column rod (36) mounted operatively connected to the steering stem (30) at its upper end, the steering stem (30) spaced apart from the steering handle (32) in order to provide for off-center steering.

Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.

Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.

Abstract: A heat sink assembly for a light fixture can include at least one heat sink fin disposed in thermal communication with at least one heat-generating component of the light fixture, where the at least one heat sink fin includes a thermoplastic material. The at least one heat sink fin can absorb and dissipate sufficient heat to comply with applicable industry standards for the light fixture.

Abstract: A portable self-administrable medication delivery device with “End of Life” feature includes a housing, a drive member within said housing, a locking element and a medicine filled container. The device further provides a “Partial Dose Prevention” feature to deliver an accurate amount of dose with precision. The device is capable of delivering multiple doses of a liquid medicament contained therein without the need of priming the injector prior to administration and allows for repeated administration of a dose of medicament in a simple, easy, safe and accurate manner.

Abstract: A heat sink assembly for a light fixture can include at least one heat sink fin disposed in thermal communication with at least one heat-generating component of the light fixture, where the at least one heat sink fin includes a thermoplastic material. The at least one heat sink fin can absorb and dissipate sufficient heat to comply with applicable industry standards for the light fixture.

Abstract: A heat sink assembly for a light fixture can include at least one heat sink fin disposed in thermal communication with at least one heat-generating component of the light fixture, where the at least one heat sink fin includes a thermoplastic material. The at least one heat sink fin can absorb and dissipate sufficient heat to comply with applicable industry standards for the light fixture.

Abstract: A package includes a container and a lid. The container includes a body formed to include an interior product-storage region and neck coupled to the body and formed to include a mouth opening into the interior-product storage region. The lid is coupled the neck of the container and formed to include a portion of a droplet passageway therein which is arranged to extend along a longitudinal axis of the lid. The droplet passageway is adapted to communicate a droplet of fluid from the interior region to environment surrounding the package.

Abstract: A heat sink assembly for a light fixture can include at least one heat sink fin disposed in thermal communication with at least one heat-generating component of the light fixture, where the at least one heat sink fin includes a thermoplastic material. The at least one heat sink fin can absorb and dissipate sufficient heat to comply with applicable industry standards for the light fixture.

Abstract: A package includes a container and a lid. The container includes a body formed to include an interior product-storage region and neck coupled to the body and formed to include a mouth opening into the interior-product storage region. The lid is coupled the neck of the container and formed to include a portion of a droplet passageway therein which is arranged to extend along a longitudinal axis of the lid. The droplet passageway is adapted to communicate a droplet of fluid from the interior region to environment surrounding the package.

Abstract: An on board inert gas generation system for an aircraft receives air from a relatively low pressure source such as low pressure engine bleed air or ram air and passes it to a positive displacement compressor to increase the pressure thereof to be suitable for supply to an air separation module. The speed of the positive displacement compressor may be adjusted across a wide range in order to provide efficient operation in cruise and descent phases of aircraft flight. The operating speed of the compressor and/or the flow rate from the ASM to the space to be inerted may be controlled in accordance with at least one of the gas composition in the space to be inerted, the flight condition, and the ullage volume.

Abstract: An on board inert gas generation system for an aircraft receives air from a relatively low pressure source such as low pressure engine bleed air or ram air and passes it to a positive displacement compressor to increase the pressure thereof to be suitable for supply to an air separation module. The positive displacement compressor comprises a high pressure ratio single stage supercharger with internal cooling.