Patents by Inventor Alok Das Mohapatra

Alok Das Mohapatra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS TO ACCEPTOR CELLS
    Publication number: 20250059569
    Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell is deficient in at least one endogenous function, for instance cytotoxic activity. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.
    Type: Application
    Filed: December 21, 2022
    Publication date: February 20, 2025
    Inventors: Bradley Joseph Kubick, Douglas Ewen Cameron, Christa Elyse Osuna, Nicolas Cordero, Edwin Xavier Arauz Diaz, Syandan Chakraborty, Lee John Flaherty, Alok Das Mohapatra, Pratibha Singh
  • Antibodies to PfGARP kill malaria parasites and protect against infection and severe disease
    Patent number: 12037386
    Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.
    Type: Grant
    Filed: May 10, 2023
    Date of Patent: July 16, 2024
    Assignee: RHODE ISLAND HOSPITAL
    Inventors: Jonathan Kurtis, Dipak K. Raj, Alok Das Mohapatra, Jenna Zuromski
  • COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS TO ACCEPTOR CELLS
    Publication number: 20240191259
    Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.
    Type: Application
    Filed: April 6, 2022
    Publication date: June 13, 2024
    Inventors: Douglas Ewen Cameron, Bradley Joseph Kubick, Christa Elyse Osuna, Nicolas Cordero, Edwin Xavier Arauz Diaz, Syandan Chakraborty, Pratibha Singh, Lee John Flaherty, Alok Das Mohapatra
  • ANTIBODIES TO PfGARP KILL PLASMODIUM FALCIPARUM MALARIA PARASITES AND PROTECT AGAINST INFECTION AND SEVERE DISEASE
    Publication number: 20240141028
    Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.
    Type: Application
    Filed: May 10, 2023
    Publication date: May 2, 2024
    Inventors: Jonathan Kurtis, Dipak K. Raj, Alok Das Mohapatra, Jenna Zuromski
  • Antibodies to PfGARP kill malaria parasites and protect against infection and severe disease
    Patent number: 11692026
    Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: July 4, 2023
    Assignee: RHODE ISLAND HOSPITAL
    Inventors: Jonathan Kurtis, Dipak K. Raj, Alok Das Mohapatra, Jenna Zuromski
  • ANTIBODIES TO PfGARP KILL PLASMODIUM FALCIPARUM MALARIA PARASITES AND PROTECT AGAINST INFECTION AND SEVERE DISEASE
    Publication number: 20210230258
    Abstract: Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria.
    Type: Application
    Filed: January 11, 2021
    Publication date: July 29, 2021
    Inventors: Jonathan Kurtis, Dipak K. Raj, Alok Das Mohapatra, Jenna Zuromski
  • High Throughput Method for Detecting Apoptosis of Embryonic Stages of Metazoan Helminthic Parasites
    Publication number: 20110124523
    Abstract: A method for detecting apoptosis of embryonic stages of parasitic helminthes. The method comprises isolating of intra uterine embryonic stages from an adult female parasite. The embryonic stages are cultured in vitro and treated. The said embryonic stages are subjected to flow cytometric analysis. An assay for apoptosis is performed being capable of high throughput screening and identification of compounds having apoptogenic activity towards the embryonic stages of helminthic parasites.
    Type: Application
    Filed: November 12, 2009
    Publication date: May 26, 2011
    Applicant: INSTITUTE OF LIFE SCIENCES
    Inventors: Balachandran Ravindran, Alok Das Mohapatra