Abstract: The present disclosure provides a method and a kit for inducing growth or regeneration of a damaged nerve of a subject, or the treatment thereof by applying a clot of blood that is withdrawn from the subject. The blood that is withdrawn from the subject is introduced to a lumen of a nerve enveloping hollow element that envelopes the damaged portion of the nerve while controllably coagulating within the lumen to form a clot on the damaged portion of the nerve. The clot, while in physical contact with the damaged portion of the nerve, enhances the rehabilitation of the nerve and may partially or fully restore its functionality.

Abstract: The present disclosure provides a method and a kit for treating an abnormal hollowed space of a subject, such as a fistula, e.g. an anal fistula or a stoma space. For example, the abnormal hollowed space can be an anal fistula, a stoma opening, or a pilonidal sinus. The method utilizes autologous blood, which is derived from the subject, by introducing it into the abnormal hollowed space and let it clot within the abnormal hollowed space thereby forming a coagulated blood mass therein, namely a blood clot, that enhances the healing process of the abnormal hollowed space. The healing may be a complete or partial closure or reduction in the size or volume of said space; or the formation of healthy tissue within the former abnormal hollowed space.

Abstract: Provided by this disclosure is a method and system for the preparation of a blood clot-based wound dressing whereby a fluid, typically gas such as air is propelled through one conduit into a sealed, blood-containing test tube, and at the same time blood s permitted to flow out of the test through a second conduit and thereby transferred into a blot clot molding space where the blood is permitted to coagulate forming a clot of a shape defined by the molding space. The propelling fluid is typically air that is propelled to flow in the first conduit by a syringe. Provide by this disclosure is also a coupling device useful in said method and system; as well as a kit of parts comprising elements needed for carrying out the method of this disclosure.

Abstract: An applicator for use in tissue treatment, a method and a kit using the same. The applicator includes (i) a first chamber for holding whole blood, (ii) a second chamber for holding a coagulation initiator, and (iii) a dispensing element configured for concomitantly receiving, upon actuating the applicator, a volume of whole blood from said first chamber and a volume of coagulation initiator from said second chamber and dispensing the two together onto a tissue in need of treatment.

Abstract: Device, method and assembly for wound treatment. Specifically a wound dressing device; an assembly, e.g. a kit-of-parts, including the device as a component; and method of wound dressing and use wherein the device is a key component. The device includes a cavity defined by concave walls surrounded by lips for attachment to skin in fluid tight manner and a closure removably fixed to the lips and sealing the cavity. The assembly also includes, as another component a device for introducing blood into the cavity after it is fixed over a wound to permit the blood to clot over the wound within the cavity. In use, the clotting mold device is fixed on top of a wound, and blood is introduced into the mold space to permit the blood to clot within the mold space to form a blood clot over the wound.

Abstract: Wound dressing assembly including (i) blood-clotting mold device having an enclosure defined between walls of a main body and a removable closure over an opening and configured for introduction of blood thereinto, and (ii) coagulation initiator in amount sufficient to coagulate blood introduced into the enclosure to form a blood clot. The formed blood clot is transferable onto a wound. Method for preparing a wound dressing by introducing a volume of blood into the enclosure of the blood-clotting mold device, maintaining the blood within the enclosure for time sufficient to permit clotting of the blood to obtain a blood clot; removing said the closure to open the enclosure; and extracting the blood clot from the enclosure. The formed blood clot may be used in a method for dressing a wound by fixation of the clot onto the wound.

Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.

Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.

Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.

Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.

Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.

Abstract: The invention provides a system and method for regional assessment of lung physiology. The system includes a plurality of sound transducers configured to be fixed on a surface of the individual over the thorax. A processor is configured to receive signals generated by the transducers and to determine from the signals a value of a parameter in each of one or more regions of the lungs. The method of the invention includes obtaining signals indicative of pressure waves at locations over the thorax; and determining from the signals a value of a parameter in each of the regions of the lungs.

Abstract: The invention provides a method and system for assessing an interventional pulmonology procedure. A plurality of sound transducers are fixed on a surface of the individual over an individual's respiratory tract that generate signals indicative of pressure waves at the transducers. A processor receives the signals and generates from the signals an image indicative of airflow in at least a portion of the respiratory tract before the interventional pulmonology procedure is carried out. A second image indicative of airflow in at least a portion of the respiratory tract is then generated from the signals after the interventional procedure has been carried out. display the first and second sequences of images simultaneously on a display device. The first and second images are then displayed on a display.